PYGB and PYGL

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PYGB	PYGL
Gene Name		phosphorylase, glycogen; brain	phosphorylase, glycogen, liver
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Membrane Extracellular Vesicular Exosome	Cytoplasm Cytosol Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Glycogen Phosphorylase Activity Pyridoxal Phosphate Binding	Purine Nucleobase Binding ATP Binding Glucose Binding Drug Binding Glycogen Phosphorylase Activity AMP Binding Vitamin Binding Pyridoxal Phosphate Binding Bile Acid Binding Protein Homodimerization Activity
	Biological Process	Carbohydrate Metabolic Process Glycogen Catabolic Process Glucose Metabolic Process Pathogenesis Small Molecule Metabolic Process	Carbohydrate Metabolic Process Glycogen Metabolic Process Glycogen Catabolic Process Glucose Metabolic Process 5-phosphoribose 1-diphosphate Biosynthetic Process Pathogenesis Glucose Homeostasis Small Molecule Metabolic Process Necroptotic Process
Pathways		Glucose metabolism Glycogen breakdown (glycogenolysis) Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates	Glucose metabolism Glycogen breakdown (glycogenolysis) Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs			Pyridoxal Phosphate Adenosine monophosphate 7,9-Dihydro-1h-Purine-2,6,8(3h)-Trione CP-526423 1-N-Acetyl-Beta-D-Glucosamine Beta-D-Glucose 5-Chloro-1h-Indole-2-Carboxylic Acid{[Cyclopentyl-(2-Hydroxy-Ethyl)-Carbamoyl]-Methyl}-Amide Cp403700, (S)-1-{2-[(5-Chloro-1h-Indole-2-Carbonyl)-Amino]-3-Phenyl-Propionyl}-Azetidine-3-Carboxylate Phosphonoserine 5-chloro-N-{4-[(1R)-1,2-dihydroxyethyl]phenyl}-1H-indole-2-carboxamide 4-[3-(2-Chloro-4,5-difluoro-benzoyl)ureido]-3-trifluoromethoxybenzoic acid 1-{2-[3-(2-Chloro-4,5-difluoro-benzoyl)-ureido]-4-fluoro-phenyl}-piperidine-4-carboxylic acid N-(2-CHLORO-4-FLUOROBENZOYL)-N\'-(5-HYDROXY-2-METHOXYPHENYL)UREA
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 22001757)	Acute lymphoblastic leukemia (childhood) ( 23007406)
Protein-Protein Interactions		3 interactors: ACTN1 PYGL SIAH1	4 interactors: BAG1 HSD3B7 IDH2 PYGB
Entrez ID		5834	5836
HPRD ID		00720	01987
Ensembl ID		ENSG00000100994	ENSG00000100504
Uniprot IDs		P11216	P06737
PDB IDs			1EM6 1EXV 1FA9 1FC0 1L5Q 1L5R 1L5S 1L7X 1XOI 2ATI 2QLL 2ZB2 3CEH 3CEJ 3CEM 3DD1 3DDS 3DDW
Enriched GO Terms of Interacting Partners?		5-phosphoribose 1-diphosphate Biosynthetic Process Protein Localization To Tight Junction Protein Localization To Cell Junction Glycogen Catabolic Process Actin Crosslink Formation Polysaccharide Catabolic Process Protein Destabilization Cellular Carbohydrate Catabolic Process Necroptotic Process Focal Adhesion Assembly Programmed Cell Death Programmed Necrotic Cell Death Cell Death Death Adherens Junction Assembly Necrotic Cell Death Tight Junction Assembly Cell-substrate Junction Assembly Neuron Apoptotic Process Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Glycogen Metabolic Process Actin Filament Bundle Assembly Neuron Death Platelet Degranulation Apical Junction Assembly	Glyoxylate Cycle Negative Regulation Of Motor Neuron Apoptotic Process Cellular Carbohydrate Metabolic Process Chaperone Cofactor-dependent Protein Refolding Energy Derivation By Oxidation Of Organic Compounds Oxidation-reduction Process Isocitrate Metabolic Process Glyoxylate Metabolic Process Generation Of Precursor Metabolites And Energy 2-oxoglutarate Metabolic Process Glycogen Catabolic Process Monocarboxylic Acid Metabolic Process Protein Refolding Small Molecule Metabolic Process Polysaccharide Catabolic Process Bile Acid Biosynthetic Process Cellular Carbohydrate Catabolic Process Bile Acid Metabolic Process Tricarboxylic Acid Cycle Citrate Metabolic Process Tricarboxylic Acid Metabolic Process Glycogen Metabolic Process Aerobic Respiration Positive Regulation Of Neuron Apoptotic Process Chaperone-mediated Protein Folding Carboxylic Acid Metabolic Process Carbohydrate Metabolic Process Protein Localization To Mitochondrion Positive Regulation Of Neuron Death Cellular Aldehyde Metabolic Process Organic Acid Metabolic Process
Tagcloud ?			coater crystallized degassing depositing diaphragm evacuated evaporable evaporated evaporation film glu glutamic handmade intramolecular lactamization molten particulates periodic preserving pyroglutamic quartz racemization resonator simply soldering spacing thin vacuum versatile
Tagcloud (Difference) ?			coater crystallized degassing depositing diaphragm evacuated evaporable evaporated evaporation film glu glutamic handmade intramolecular lactamization molten particulates periodic preserving pyroglutamic quartz racemization resonator simply soldering spacing thin vacuum versatile
Tagcloud (Intersection) ?