PYCR1 and NUDT21

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		PYCR1	NUDT21
Gene Name		pyrroline-5-carboxylate reductase 1	nudix (nucleoside diphosphate linked moiety X)-type motif 21
Image
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nucleus Nucleoplasm Centrosome MRNA Cleavage Factor Complex Paraspeckles
	Molecular Function	Pyrroline-5-carboxylate Reductase Activity Protein Binding Identical Protein Binding	RNA Binding MRNA Binding Protein Binding Hydrolase Activity AU-rich Element Binding Protein Homodimerization Activity Histone Deacetylase Binding Poly(A) RNA Binding
	Biological Process	Proline Biosynthetic Process Cellular Amino Acid Biosynthetic Process Cellular Response To Oxidative Stress Cellular Nitrogen Compound Metabolic Process Small Molecule Metabolic Process Regulation Of Mitochondrial Membrane Potential Oxidation-reduction Process L-proline Biosynthetic Process Negative Regulation Of Hydrogen Peroxide-induced Cell Death	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Polyadenylation MRNA Processing RNA Splicing Gene Expression MRNA 3'-end Processing Protein Tetramerization
Pathways		Amino acid synthesis and interconversion (transamination) Metabolism of amino acids and derivatives	mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs mRNA 3'-end processing
Drugs		NADH L-Proline
Diseases
GWAS
Protein-Protein Interactions		4 interactors: BNIPL CDK2AP2 HNRNPD NUDT21	51 interactors: A2M ATXN1 CARM1 CLP1 CPSF6 CPSF7 CTNND2 DBN1 DNMT3L DYNC1I1 EED EEF1G EXOSC6 F13A1 FBN3 FLAD1 FUNDC2 GOLGA2 HSF4 IKZF1 ITCH JMJD1C KIAA1377 KIFAP3 MASP1 MYL6 NEDD4 NGEF NIF3L1 POLR2C PSMF1 PTN PYCR1 RBM48 RCC1 RNF19A RPLP1 SEMA5B SF3B1 SHC1 SHFM1 SLC44A1 SNCAIP SNRNP70 SRPK1 TCERG1 TLE1 TRA2A TRIM27 WWOX ZBTB48
Entrez ID		5831	11051
HPRD ID		01528	05400
Ensembl ID		ENSG00000183010	ENSG00000167005
Uniprot IDs		B4DMU0 E2QRB3 P32322 Q8TBX0	O43809
PDB IDs		2GER 2GR9 2GRA 2IZZ	2CL3 2J8Q 3BAP 3BHO 3MDG 3MDI 3N9U 3P5T 3P6Y 3Q2S 3Q2T
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Growth Rate RNA Splicing Circadian Regulation Of Translation MRNA Processing MRNA Metabolic Process RNA Processing MRNA Polyadenylation RNA Polyadenylation Termination Of RNA Polymerase II Transcription Regulation Of MRNA Stability Regulation Of RNA Stability	Gene Expression Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process MRNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Processing MRNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Process Cellular Metabolic Process Viral Process Protein K63-linked Ubiquitination RNA Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Metabolic Process Protein Polyubiquitination Negative Regulation Of Complement Activation MRNA 3'-end Processing Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Immune System Process Developmental Process RNA 3'-end Processing Cellular Macromolecule Biosynthetic Process Regulation Of Dendrite Development Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression By Genetic Imprinting Blood Coagulation Macromolecule Biosynthetic Process Hemostasis Protein Oligomerization MRNA Polyadenylation Anatomical Structure Development
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?