NUDT21 and SEMA5B

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		NUDT21	SEMA5B
Description		nudix hydrolase 21	semaphorin 5B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome MRNA Cleavage And Polyadenylation Specificity Factor Complex MRNA Cleavage Factor Complex Nuclear Body Centriolar Satellite Paraspeckles	Plasma Membrane Membrane
	Molecular Function	Chromatin Binding RNA Binding MRNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding Identical Protein Binding Protein Homodimerization Activity Histone Deacetylase Binding	Semaphorin Receptor Binding Chemorepellent Activity
	Biological Process	MRNA Processing Post-transcriptional Regulation Of Gene Expression Cell Differentiation MRNA 3'-end Processing Protein Tetramerization Protein Heterotetramerization MRNA Alternative Polyadenylation Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway Positive Regulation Of Stem Cell Differentiation Positive Regulation Of Pro-B Cell Differentiation	Neural Crest Cell Migration Nervous System Development Axon Guidance Cell Differentiation Positive Regulation Of Cell Migration Axon Extension Detection Of Light Stimulus Involved In Visual Perception Negative Chemotaxis Semaphorin-plexin Signaling Pathway Neuron Projection Guidance Neuron Projection Extension
Pathways		mRNA 3'-end processing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs	Defective B3GALTL causes PpS O-glycosylation of TSR domain-containing proteins
Drugs
Diseases
GWAS			Cortex volume ( 31530798) Esophageal cancer ( 21642993) Gut microbiota relative abundance (unclassified genus belonging to family Clostridiaceae) ( 33208821) Serum albumin levels ( 29403010) Total grey matter volume ( 31530798)
Interacting Genes		119 interacting genes: A2M ATXN1 CARM1 CDC42 CEBPA CEP126 CLP1 CPSF6 CPSF7 CTNND2 DBN1 DNMT3L DYNC1I1 EED EEF1G ESR1 EXOSC6 F13A1 FAM90A1 FBN3 FLAD1 FUNDC2 GOLGA2 HSF4 IKZF1 ITCH JMJD1C KIFAP3 KRT75 MASP1 MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-2 MIR138-1 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200B MIR205 MIR206 MIR20A MIR214 MIR221 MIR25 MIR29A MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-2 MIR9-2 MIR92A1 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I MYL6 NEDD4 NGEF NIF3L1 NTAQ1 POLR2C PSMF1 PSPC1 PTN PYCR1 RBM48 RCC1 RNF19A RPLP1 S100PBP SEM1 SEMA5B SF3B1 SHC1 SLC44A1 SNCAIP SNRNP70 SPAG8 SRPK1 TCERG1 TEPSIN TLE1 TRA2A TRIM23 TRIM27 WWOX ZNF655	8 interacting genes: ANXA7 C11orf58 FAM118B MRPL44 NUDT21 SMN1 SPRY2 TK1
Entrez ID		11051	54437
HPRD ID		05400	15322
Ensembl ID		ENSG00000167005	ENSG00000082684
Uniprot IDs		O43809	A0A3B3IRP9 A0A3B3IT43 B7Z2B3 C9JKR3 Q9P283
PDB IDs		2CL3 2J8Q 3BAP 3BHO 3MDG 3MDI 3N9U 3P5T 3P6Y 3Q2S 3Q2T 5R4P 5R4Q 5R4R 5R4S 5R4T 5R4U 5R64 5R65 5R66 5R67
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing RISC Complex MRNA Base-pairing Post-transcriptional Repressor Activity Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Extracellular Vesicle MiRNA-mediated Gene Silencing By MRNA Destabilization Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Negative Regulation Of Translation Regulation Of Angiogenesis Regulation Of Vasculature Development Negative Regulation Of Vascular Endothelial Growth Factor Production Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Blood Vessel Endothelial Cell Migration MRNA Destabilization Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Cell Migration RNA Destabilization Negative Regulation Of Cytokine Production Negative Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cell Motility Positive Regulation Of MRNA Catabolic Process Negative Regulation Of Locomotion Regulation Of Macromolecule Metabolic Process Regulation Of Endothelial Cell Migration Negative Regulation Of Multicellular Organismal Process Regulation Of Cell Migration Involved In Sprouting Angiogenesis Negative Regulation Of Endothelial Cell Migration Positive Regulation Of Tissue Remodeling Negative Regulation Of Developmental Process Negative Regulation Of Sprouting Angiogenesis Regulation Of Metabolic Process Positive Regulation Of Connective Tissue Replacement Regulation Of Translation Negative Regulation Of Cell Migration Involved In Sprouting Angiogenesis Regulation Of Anatomical Structure Morphogenesis Negative Regulation Of Signal Transduction Regulation Of Sprouting Angiogenesis Negative Regulation Of Protein Metabolic Process	RNA Binding Chromaffin Granule Membrane Cajal Body Nuclear Body DNA Synthesis Involved In Mitotic DNA Replication Thymidine Metabolic Process Protein Tetramerization Thymidine Biosynthetic Process Thymidine Kinase Activity Bud Elongation Involved In Lung Branching Regulation Of Lens Fiber Cell Differentiation Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Ubiquitin-protein Transferase Inhibitor Activity Lung Growth Respiratory System Development Microtubule End Negative Regulation Of Lens Fiber Cell Differentiation MRNA Cleavage Factor Complex Regulation Of Pro-B Cell Differentiation Positive Regulation Of Hematopoietic Progenitor Cell Differentiation MRNA Alternative Polyadenylation Positive Regulation Of Lymphoid Progenitor Cell Differentiation Positive Regulation Of Pro-B Cell Differentiation Ribonuclease III Activity Mitochondrial Translational Elongation Deoxyribonucleoside Monophosphate Biosynthetic Process Co-transcriptional MRNA 3'-end Processing, Cleavage And Polyadenylation Pathway Response To Phorbol 13-acetate 12-myristate Nucleus SMN Complex RNA Processing Identical Protein Binding Gemini Of Cajal Bodies Pyrimidine Nucleoside Metabolic Process Protein Complex Oligomerization Regulation Of Neurotrophin TRK Receptor Signaling Pathway Branch Elongation Of An Epithelium Paraspeckles Regulation Of Lymphoid Progenitor Cell Differentiation Co-transcriptional RNA 3'-end Processing, Cleavage And Polyadenylation Pathway
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