ECI2

Description		enoyl-CoA delta isomerase 2
Image
GO Annotations	Cellular Component	Mitochondrion Peroxisome Peroxisomal Matrix Cytosol Membrane
	Molecular Function	Fatty-acyl-CoA Binding Delta(3)-delta(2)-enoyl-CoA Isomerase Activity Protein Binding Isomerase Activity
	Biological Process	Fatty Acid Beta-oxidation Fatty Acid Catabolic Process
Pathways
Drugs		Myristic acid
Diseases
GWAS		Blood protein levels ( 30072576) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661)
Interacting Genes		4 interacting genes: APP KDM1A PEX5 TNPO3
Entrez ID		10455
HPRD ID		16269
Ensembl ID		ENSG00000198721
Uniprot IDs		A0A0C4DGA2 O75521
PDB IDs		2CQU 2F6Q 4U18 4U19 4U1A
Enriched GO Terms of Interacting Partners?		Neuron Maturation Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Response To Purine-containing Compound Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Cellular Response To Oxygen-containing Compound Enzyme Binding Regulation Of Response To Calcium Ion Regulation Of Multicellular Organism Growth Amylin Binding Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To CAMP Cell Development Protein-containing Complex Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Peroxisome Membrane Targeting Sequence Binding Peroxisome Matrix Targeting Signal-1 Binding Peroxisome Targeting Sequence Binding Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Regulation Of Intrinsic Apoptotic Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Developmental Maturation Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Protein Import Into Peroxisome Matrix, Translocation Protein Import Into Peroxisome Matrix, Docking Protein Demethylase Activity Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon MRF Binding
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