NGB and NIF3L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NGB	NIF3L1
Description		neuroglobin	NGG1 interacting factor 3 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol	Nucleus Cytoplasm Mitochondrion
	Molecular Function	GDP-dissociation Inhibitor Activity Oxygen Carrier Activity Protein Binding Oxidoreductase Activity Oxygen Binding Heme Binding Metal Ion Binding Nitrite Reductase Activity	Protein Binding Identical Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding
	Biological Process	Response To Hypoxia Oxygen Transport Cellular Response To Hypoxia	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Neuron Differentiation Positive Regulation Of DNA-templated Transcription
Pathways		Intracellular oxygen transport
Drugs
Diseases
GWAS			Triptolide cytotoxicity ( 26121980)
Interacting Genes		23 interacting genes: AKT1 ATP1B2 BTBD2 C1orf94 DDIT4L FLOT1 GATAD2B GNAI1 GNAI2 GNAI3 GNAO1 IHO1 L3MBTL3 MAPK14 MEI4 NIF3L1 OTOS PTEN REL TDO2 TEPSIN VAC14 ZNF655	93 interacting genes: ALKBH4 AP5B1 APIP ARPIN BDKRB2 BEND7 C14orf119 CASP7 CCDC102B CCDC85B CDKN2B CDKN2C CDKN2D COIL COPS2 CUTC CYRIB DCDC2 DCTD DCTPP1 DHPS DMC1 DMRTB1 DTX2 DUSP23 DUSP29 DYNLT3 EIF4A3 EIF5A2 ENOX1 EPHB6 FLAD1 FXR2 GNMT GRB2 IP6K3 KCNIP1 KCTD17 KCTD7 KCTD9 KRT15 KXD1 LAMTOR3 LMO2 LMO3 MAGEA11 MAPRE2 MLXIPL NATD1 NEK6 NGB NME1 NME7 NOL3 NUDT14 NUDT21 ORC5 PAFAH1B3 PAICS PCBD1 PNMA1 POLR1C PPIH PRTFDC1 PTPA RABAC1 RAD54B RPIA S100A1 SAT1 SEPTIN1 SNF8 SPG21 SSX2IP STAT3 STK16 SULT1A2 SULT1A3 SULT2A1 SYT17 TCL1A THOC7 TIFA TRAF2 TRIM21 TRIM27 TRIP13 TSC22D4 TXN VIM YES1 YWHAQ ZBED1
Entrez ID		58157	60491
HPRD ID		05602	10424
Ensembl ID		ENSG00000165553	ENSG00000196290
Uniprot IDs		A0M8W9 Q9NPG2	Q9GZT8
PDB IDs		1OJ6 4MPM 7VQG 8GRZ 8WUB
Enriched GO Terms of Interacting Partners?		Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway G Protein-coupled Serotonin Receptor Binding Adenylate Cyclase Regulator Activity Meiotic DNA Double-strand Break Formation Adenylate Cyclase-inhibiting Serotonin Receptor Signaling Pathway Negative Regulation Of Adenylate Cyclase Activity G Protein-coupled Receptor Binding Regulation Of Transport Myelin Maintenance Positive Regulation Of Myoblast Fusion Regulation Of Organ Growth Negative Regulation Of Transport Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Cycle Process Regulation Of Myoblast Fusion G Protein-coupled Serotonin Receptor Signaling Pathway Positive Regulation Of Syncytium Formation By Plasma Membrane Fusion Regulation Of Peptidyl-serine Phosphorylation Osteoblast Differentiation Response To Prostaglandin E Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Cholesterol Metabolic Process Cellular Response To Vascular Endothelial Growth Factor Stimulus Ciliary Basal Body Regulation Of Cholesterol Biosynthetic Process Centriolar Satellite Homologous Chromosome Pairing At Meiosis Positive Regulation Of Sodium Ion Transport GTPase Activity Positive Regulation Of D-glucose Import Regulation Of Smooth Muscle Cell Proliferation Regulation Of TRNA Methylation Positive Regulation Of Steroid Biosynthetic Process Lipopolysaccharide-mediated Signaling Pathway Neuronal-glial Interaction Involved In Hindbrain Glial-mediated Radial Cell Migration Negative Regulation Of Secretion By Cell Biotin--[biotin Carboxyl-carrier Protein] Ligase Activity Negative Regulation Of Synaptic Vesicle Clustering L-tryptophan Catabolic Process To Acetyl-CoA PAS Complex Coated Vesicle Membrane Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Insulin Secretion GTP Binding Positive Regulation Of Steroid Metabolic Process	Identical Protein Binding Cytoplasm Protein Binding Cytosol Protein Complex Oligomerization Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Ethanol Catabolic Process Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Ethanol Metabolic Process Nucleoside Phosphate Metabolic Process Phosphate-containing Compound Metabolic Process Sulfation Pyrimidine Nucleotide Metabolic Process Polyamine Catabolic Process Nucleus Ribose Phosphate Metabolic Process Reciprocal Meiotic Recombination
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