FKBP7 and SUCLA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FKBP7	SUCLA2
Description		FKBP prolyl isomerase 7	succinate-CoA ligase ADP-forming subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Lumen	Cytoplasm Mitochondrion Mitochondrial Matrix Succinate-CoA Ligase Complex (ADP-forming) Succinate-CoA Ligase Complex Extracellular Exosome
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Calcium Ion Binding Protein Binding FK506 Binding Isomerase Activity Metal Ion Binding	Nucleotide Binding Magnesium Ion Binding Catalytic Activity Succinate-CoA Ligase (ADP-forming) Activity Protein Binding ATP Binding Ligase Activity Metal Ion Binding
	Biological Process		Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process Succinyl-CoA Pathway Succinyl-CoA Catabolic Process
Pathways			Citric acid cycle (TCA cycle)
Drugs
Diseases			Mitochondrial DNA depletion syndrome (MDS)
GWAS		Alanine aminotransferase levels ( 33547301) Appendicular lean mass ( 33097823) Aspartate aminotransferase levels ( 33547301) Atrial fibrillation ( 30061737) Blood protein levels ( 30072576) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Refractive error ( 32231278)	Aging (time to event) ( 21782286) Colorectal cancer (diet interaction) ( 24743840) Proportion of activated microglia (inferior temporal cortex) ( 30679421) Serum metabolite levels ( 33031748) Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		107 interacting genes: ABHD16A ADGRE2 ADIPOQ AP1M1 APOD ASPH BET1 BMP10 BRICD5 C3orf52 CD81 CDIPT CDS2 CERCAM CFTR CIAO2A CLCA4 CLDN19 CNIH1 CTSA CXCL16 CYB561D2 CYB5B DIABLO ERMP1 FAM3C FARS2 GET3 H4C7 HHATL HMOX1 HSBP1L1 HTATIP2 IER3 IFITM3 IGFBP5 IRF2 JOSD2 LAT LNPEP MAN2B2 MIEF2 MRM1 NFU1 NKG7 NPFFR2 OCIAD1 OXNAD1 PBX3 PCYT1A PEX16 PEX19 PLLP PLP1 PLP2 PLPP6 PPIF PRMT6 PTCD1 PTPN9 RBFA RPRM RUSF1 SELENOK SERP1 SGTA SLC30A3 SLC38A7 SLC7A14 SNX1 SNX12 STATH STX7 STX8 SUCLA2 TARS2 TCP11X2 TECR TF THAP4 THSD7B TMEM108 TMEM120B TMEM147 TMEM14A TMEM229B TMEM239 TMEM54 TMEM86A TMEM86B TMEM97 TRAM1L1 TSPAN2 TSPO2 TTPA TXNDC12 UBIAD1 UBQLN4 UNC93B1 UPK1B UPK2 VSTM4 WFDC2 WIPI2 YIPF4 YIPF6 ZFPL1	11 interacting genes: AGTRAP ALAS2 ARL6IP1 CMTM5 FAM9B FKBP7 MAGEA11 MAL2 MTNR1A SEC23A TNFRSF10D
Entrez ID		51661	8803
HPRD ID		08451	06798
Ensembl ID		ENSG00000079150	ENSG00000136143
Uniprot IDs		B4DRE2 Q9Y680	E5KS60 Q9P2R7
PDB IDs			6G4Q
Enriched GO Terms of Interacting Partners?		Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Protein Binding Chloride Channel Inhibitor Activity Regulation Of Cellular Localization Cellular Localization Protein Insertion Into ER Membrane Transferrin Receptor Binding Alkenylglycerophosphocholine Hydrolase Activity Lysosome Peroxisome Membrane Biogenesis Intraciliary Transport Particle B Binding Cholesterol Binding Establishment Of Localization In Cell
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