RAB40C and TOE1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		RAB40C	TOE1
Description		RAB40C, member RAS oncogene family	target of EGR1, exonuclease
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Plasma Membrane Synaptic Vesicle Membrane Cul5-RING Ubiquitin Ligase Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Cajal Body Nuclear Body Nuclear Speck
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding Ubiquitin-like Ligase-substrate Adaptor Activity	3'-5'-RNA Exonuclease Activity Nucleic Acid Binding Poly(A)-specific Ribonuclease Activity Protein Binding Zinc Ion Binding SnRNA Binding Metal Ion Binding
	Biological Process	Exocytosis Cell Migration Protein Ubiquitination Intracellular Signal Transduction Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Focal Adhesion Assembly Negative Regulation Of Focal Adhesion Assembly Lipid Droplet Formation	RNA Metabolic Process SnRNA 3'-end Processing
Pathways		RAB geranylgeranylation
Drugs
Diseases
GWAS		Adiponectin levels ( 33562295) Disc degeneration (lumbar) ( 22993228) Height ( 18391950) Hip circumference adjusted for BMI ( 34021172) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494)
Interacting Genes		3 interacting genes: ANKRD27 PSD TOE1	27 interacting genes: ABCF3 AGGF1 ANXA1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 OGT PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83
Entrez ID		57799	114034
HPRD ID		10182	18212
Ensembl ID		ENSG00000197562	ENSG00000132773
Uniprot IDs		Q96S21	B4DP23 Q96GM8
PDB IDs			2FC6
Enriched GO Terms of Interacting Partners?		Guanyl-nucleotide Exchange Factor Activity Negative Regulation Of SNARE Complex Assembly Negative Regulation Of Vesicle Fusion Tubular Endosome Endosome To Melanosome Transport SnRNA Binding Poly(A)-specific Ribonuclease Activity Regulation Of SNARE Complex Assembly Postsynaptic Density, Intracellular Component Regulation Of ARF Protein Signal Transduction SnRNA 3'-end Processing Early Endosome To Late Endosome Transport Positive Regulation Of Dendrite Morphogenesis Regulation Of Vesicle Fusion SnRNA Processing 3'-5'-RNA Exonuclease Activity	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Spliceosomal Complex MRNA Processing MRNA Metabolic Process Catalytic Step 2 Spliceosome RNA Metabolic Process Nucleoplasm Nuclear Speck Regulation Of RNA Splicing RNA Processing Nucleic Acid Metabolic Process Macromolecule Metabolic Process U2-type Precatalytic Spliceosome Nucleobase-containing Compound Metabolic Process Protein-RNA Complex Assembly Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome RS Domain Binding Regulation Of MRNA Processing Glutamatergic Synapse Cadherin Binding Involved In Cell-cell Adhesion RNA Binding Transition Metal Ion Binding U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2 SnRNP Membraneless Organelle Assembly U2-type Spliceosomal Complex Regulation Of Programmed Cell Death Alpha-2B Adrenergic Receptor Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Synaptic Vesicle Priming Oocyte Axis Specification
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