SLC7A14 and IL10RA

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC7A14	IL10RA
Description		solute carrier family 7 member 14	interleukin 10 receptor subunit alpha
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Lysosome Lysosomal Membrane Cytosol Plasma Membrane Membrane	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cilium Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding Amino Acid Transmembrane Transporter Activity Gamma-aminobutyric Acid Transmembrane Transporter Activity Transmembrane Transporter Activity	Interleukin-10 Receptor Activity Protein Binding Interleukin-10 Binding Signaling Receptor Activity
	Biological Process	Amino Acid Transmembrane Transport Amino Acid Transport Gamma-aminobutyric Acid Import Transmembrane Transport	Negative Regulation Of Autophagy Cytokine-mediated Signaling Pathway Response To Lipopolysaccharide Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Inflammatory Response Regulation Of Synapse Organization Intestinal Epithelial Structure Maintenance Ubiquitin-dependent Endocytosis Interleukin-10-mediated Signaling Pathway
Pathways			Interleukin-10 signaling Nuclear events stimulated by ALK signaling in cancer
Drugs
Diseases
GWAS		Obesity (extreme) ( 30677029) Spontaneous preterm birth without premature rupture of membranes ( 31194736)	Obesity-related traits ( 23251661)
Interacting Genes		47 interacting genes: ACSL5 ADGRE2 AGTRAP AIG1 APOL3 BET1 BNIP1 BNIP2 C1GALT1 CBLIF CCDC167 CCL4L2 CD53 CMTM5 DCBLD2 DERL1 EOGT ERMP1 FAM209A FAM20B FATE1 FCER1G FKBP7 IL10RA LINC00839 LTC4S MFF MGLL MMGT1 NINJ2 NSG1 PLPP6 PRB1 SCARF1 SCD SMCO4 TECR TMEM128 TMEM31 TRARG1 TREX1 UBIAD1 VAMP2 VKORC1 YIPF4 YIPF6 ZFPL1	20 interacting genes: BTRC C1QL4 CDS2 CMTM3 HACD1 IL10 IL10RB JAK1 MAL NIPAL4 PLPP6 RUSF1 SELENOK SLC38A7 SLC66A2 SLC7A14 SMCO4 TMEM242 TMUB2 YIPF6
Entrez ID		57709	3587
HPRD ID		17222	00911
Ensembl ID		ENSG00000013293	ENSG00000110324
Uniprot IDs		Q8TBB6	Q13651
PDB IDs			1J7V 1LQS 1Y6K 1Y6M 1Y6N 5IXI 6X93
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organelle Membrane Fusion Organelle Fusion Vesicle-mediated Transport Membrane Fusion SNAP Receptor Activity Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Vesicle Fusion Vesicle Fusion With Golgi Apparatus Cobalt Ion Transport SNARE Complex Nuclear Envelope Fatty Acid Biosynthetic Process Intestinal Epithelial Cell Development Response To Oxygen-glucose Deprivation Establishment Of Protein Localization To Plasma Membrane Vitamin K Metabolic Process Endosome To Plasma Membrane Protein Transport Endomembrane System Columnar/cuboidal Epithelial Cell Development Golgi Vesicle Transport	Interleukin-10-mediated Signaling Pathway Membrane Response To Inactivity Type III Interferon-mediated Signaling Pathway
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