APOBEC3G and APOBEC3F

Number of citations of the paper that reports this interaction (PMID 15152192)
204

Data Source:
HPRD (in vivo)

		APOBEC3G	APOBEC3F
Gene Name		apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
Image
Gene Ontology Annotations	Cellular Component	Cytoplasmic MRNA Processing Body Cytoplasm Cytosol Ribonucleoprotein Complex Apolipoprotein B MRNA Editing Enzyme Complex	Cytoplasmic MRNA Processing Body Cytoplasm Ribonucleoprotein Complex Apolipoprotein B MRNA Editing Enzyme Complex
	Molecular Function	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Protein Homodimerization Activity Deoxycytidine Deaminase Activity	RNA Binding Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Poly(A) RNA Binding
	Biological Process	Positive Regulation Of Defense Response To Virus By Host Cytidine Deamination Negative Regulation Of Transposition Viral Process Base Conversion Or Substitution Editing Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Viral Process Defense Response To Virus DNA Cytosine Deamination	Positive Regulation Of Defense Response To Virus By Host Cytidine Deamination Negative Regulation Of Transposition Base Conversion Or Substitution Editing Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Viral Process Defense Response To Virus DNA Cytosine Deamination DNA Demethylation
Pathways
Drugs
Diseases
GWAS		Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		4 interactors: APOBEC3F APP PRKACA PTN	3 interactors: ACD APOBEC3G TINF2
Entrez ID		60489	200316
HPRD ID		06172	16415
Ensembl ID		ENSG00000239713
Uniprot IDs		Q9HC16	Q8IUX4
PDB IDs		2JYW 2KBO 2KEM 3E1U 3IQS 3IR2 3V4J 3V4K	4IOU
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Catalytic Activity Positive Regulation Of Mitotic Cell Cycle Innate Immune Response Positive Regulation Of Dense Core Granule Biogenesis Learning Regulation Of Protein Binding Cell Maturation Synaptic Growth At Neuromuscular Junction Histone H3-T6 Phosphorylation Platelet Activation Regulation Of Peptidyl-tyrosine Phosphorylation Collateral Sprouting In Absence Of Injury Positive Regulation Of Cell Cycle Process Immune Response Defense Response Regulation Of Binding Learning Or Memory DNA Cytosine Deamination Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Cell Cycle Cognition Cellular Calcium Ion Homeostasis Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Calcium Ion Homeostasis Peptidyl-serine Autophosphorylation Base Conversion Or Substitution Editing Axon Choice Point Recognition Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Cellular Response To Parathyroid Hormone Stimulus Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning Response To Light Stimulus Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Transposition DNA Deamination Cytidine Deamination Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Extracellular Matrix Organization Extracellular Structure Organization Desmosome Assembly Neuron Remodeling Negative Regulation Of Glial Cell Apoptotic Process Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Tight Junction Assembly Regulation Of Protein Processing Cellular Metal Ion Homeostasis Response To External Stimulus Regulation Of Mitotic Cell Cycle Negative Regulation Of Glucose Import	Negative Regulation Of DNA Metabolic Process Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Protein Localization To Chromosome Negative Regulation Of DNA Replication Telomere Maintenance Negative Regulation Of Chromosome Organization Regulation Of DNA Replication DNA Metabolic Process Positive Regulation Of DNA Metabolic Process Negative Regulation Of Protein ADP-ribosylation Positive Regulation Of Single-stranded Telomeric DNA Binding Regulation Of Chromosome Organization Regulation Of Protein ADP-ribosylation Negative Regulation Of Protein Glycosylation Protection From Non-homologous End Joining At Telomere DNA Cytosine Deamination Telomere Capping Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Cellular Metabolic Process Base Conversion Or Substitution Editing Positive Regulation Of Telomerase Activity Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate DNA Deamination Cytidine Deamination Negative Regulation Of Transposition Regulation Of Protein Glycosylation Positive Regulation Of Telomere Maintenance Protein Localization To Organelle Negative Regulation Of Glycoprotein Metabolic Process Regulation Of Telomerase Activity Positive Regulation Of Defense Response To Virus By Host Pyrimidine Nucleoside Catabolic Process Positive Regulation Of DNA Biosynthetic Process Regulation Of Glycoprotein Biosynthetic Process Regulation Of Defense Response To Virus By Host Telomere Maintenance Via Telomere Lengthening Regulation Of Organelle Organization Positive Regulation Of DNA Binding Chromosome Organization Negative Regulation Of Viral Genome Replication Regulation Of DNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of DNA Replication
Tagcloud ?		7sl a3f a3g assortment cytidine deaminases deltanc divergent editing encapsidate encapsidation engage exploit gag grna hv iclip incompletely indiscriminate nc nucleocapsid packaged packaging retroviral rnas unbiased virions	7sl a3f a3g assortment cytidine deaminases deltanc divergent editing encapsidate encapsidation engage exploit gag grna hv iclip incompletely indiscriminate nc nucleocapsid packaged packaging retroviral rnas unbiased virions
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		7sl a3f a3g assortment cytidine deaminases deltanc divergent editing encapsidate encapsidation engage exploit gag grna hv iclip incompletely indiscriminate nc nucleocapsid packaged packaging retroviral rnas unbiased virions