AMIGO1 and TMEM79

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AMIGO1	TMEM79
Description		adhesion molecule with Ig like domain 1	transmembrane protein 79
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Axon Dendrite Neuronal Cell Body Membrane Cell Projection Neuron Projection Neuronal Cell Body Perikaryon Pericellular Basket	Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Membrane Trans-Golgi Network Membrane
	Molecular Function	Protein Binding Potassium Channel Regulator Activity	Protein Binding Identical Protein Binding
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Nervous System Development Axonogenesis Axonal Fasciculation Brain Development Positive Regulation Of Neuron Projection Development Cell Differentiation Myelination Positive Regulation Of Axonogenesis Positive Regulation Of Cellular Component Organization Positive Regulation Of Nervous System Development Positive Regulation Of Synapse Assembly Neuron Projection Fasciculation Positive Regulation Of Potassium Ion Transmembrane Transport Cellular Response To L-glutamate	Epithelial Cell Maturation Hair Follicle Morphogenesis Cuticle Development Regulated Exocytosis Positive Regulation Of Epidermis Development Establishment Of Skin Barrier Cornification
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) LDL cholesterol levels ( 32203549) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)	Glycated hemoglobin levels ( 24647736 28898252 29170429) Mean corpuscular hemoglobin concentration ( 20139978)
Interacting Genes		35 interacting genes: ADIPOQ AMIGO2 AMIGO3 ANKRD46 ASGR1 BNIP3 C3orf52 CLDN11 CXCL9 EDDM3B GJB2 HHATL IGFBP5 LMO3 MALL NINJ2 NKG7 PGA4 PGAP2 PLPP6 PROM2 PTTG1IP RPRM SELENOK SLC38A1 SLC38A7 SLC41A1 STX8 TM4SF5 TMEM50B TMEM60 TMEM79 TNMD TSPO UPK2	36 interacting genes: ABO AMIGO1 ANKRD46 APOD ARL13B BRICD5 CLEC7A COQ9 CPLX4 CYB5R3 FAM209A FNDC9 GIMAP1 GPRC5D LDLRAD1 LPAR3 PELI2 PLN PLP2 PVR RNF8 RPRM SEC22A SERP1 SFTPC SLN TEX264 TMEM100 TMEM14C TMEM254 TMEM97 TMPRSS2 TMPRSS4 TNMD TRAM1L1 ZCCHC12
Entrez ID		57463	84283
HPRD ID		11129	17481
Ensembl ID		ENSG00000181754	ENSG00000163472
Uniprot IDs		Q86WK6	Q9BSE2
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Cholesterol Binding Glutamine Transport L-glutamine Transmembrane Transporter Activity	Membrane Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Endoplasmic Reticulum Endoplasmic Reticulum Membrane Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of Intracellular Transport Negative Regulation Of ATP-dependent Activity Negative Regulation Of Calcium Ion Import Positive Regulation Of Viral Entry Into Host Cell Regulation Of Relaxation Of Muscle
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