AMIGO1 and SLC38A7

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AMIGO1	SLC38A7
Description		adhesion molecule with Ig like domain 1	solute carrier family 38 member 7
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Potassium Channel Complex Membrane Axon Dendrite Neuronal Cell Body Membrane Cell Projection Neuron Projection Neuronal Cell Body Perikaryon Pericellular Basket	Lysosome Lysosomal Membrane Membrane Axon Cell Projection Neuronal Cell Body
	Molecular Function	Protein Binding Potassium Channel Regulator Activity	Protein Binding L-asparagine Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity
	Biological Process	Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Nervous System Development Axonogenesis Axonal Fasciculation Brain Development Positive Regulation Of Neuron Projection Development Cell Differentiation Myelination Positive Regulation Of Axonogenesis Positive Regulation Of Cellular Component Organization Positive Regulation Of Nervous System Development Positive Regulation Of Synapse Assembly Neuron Projection Fasciculation Positive Regulation Of Potassium Ion Transmembrane Transport Cellular Response To L-glutamate	Amino Acid Transmembrane Transport Monoatomic Ion Transport Sodium Ion Transport Amino Acid Transport Asparagine Transport Glutamine Transport
Pathways
Drugs
Diseases
GWAS		Chronic kidney disease ( 20383146) Intelligence (MTAG) ( 29326435) LDL cholesterol levels ( 32203549) Schizophrenia, bipolar disorder or major depressive disorder x sex interaction (3df) ( 34099189)	HDL cholesterol levels in HIV infection ( 33109212) Plasma anastrozole concentration in anastrozole-treated estrogen receptor positive breast cancer ( 30648747) QT interval ( 19305408) Schizophrenia ( 25056061 29483656) Suicide attempt severity in mood disorders ( 33783297)
Interacting Genes		35 interacting genes: ADIPOQ AMIGO2 AMIGO3 ANKRD46 ASGR1 BNIP3 C3orf52 CLDN11 CXCL9 EDDM3B GJB2 HHATL IGFBP5 LMO3 MALL NINJ2 NKG7 PGA4 PGAP2 PLPP6 PROM2 PTTG1IP RPRM SELENOK SLC38A1 SLC38A7 SLC41A1 STX8 TM4SF5 TMEM50B TMEM60 TMEM79 TNMD TSPO UPK2	59 interacting genes: ACBD5 AMIGO1 APH1A AQP2 AQP6 AQP9 ARL13B BTNL9 CFTR CLCN7 CLDN7 CLEC10A CPLX4 CREB3L3 CYB561 CYB5R3 EDA ERGIC3 ERP29 EVI2B FAM209A FCER1G FFAR2 FKBP7 GJA8 GJB5 GPR152 GPR42 GPX8 IL10RA KIR2DL3 LMNA LY6G6C LYVE1 MMGT1 MUC1 ODF4 OPRM1 PANX1 PDCD1LG2 RNF5 SAR1A SCN3B SERP2 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SLC35H1 SPINT1 SSMEM1 SYPL2 TMEM237 TMEM52B TSPAN8 YIPF6
Entrez ID		57463	55238
HPRD ID		11129	07701
Ensembl ID		ENSG00000181754	ENSG00000103042
Uniprot IDs		Q86WK6	H3BMC5 Q9NVC3
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Cholesterol Binding Glutamine Transport L-glutamine Transmembrane Transporter Activity	Membrane Transmembrane Transport Plasma Membrane Protein Binding Organic Hydroxy Compound Transport Water Transport Fluid Transport Channel Activity Water Channel Activity Gap Junction Channel Activity Monoatomic Ion Transport Positive Regulation Of Acute Inflammatory Response Gap Junction Bile Acid:sodium Symporter Activity Endoplasmic Reticulum Basolateral Plasma Membrane Organic Anion Transport Endoplasmic Reticulum Membrane Monoatomic Cation Transport Glycerol Transmembrane Transport Renal Water Transport Monoatomic Anion Channel Activity Polyol Transmembrane Transport Carbohydrate Transmembrane Transport Regulation Of Acute Inflammatory Response Inorganic Ion Transmembrane Transport Carbohydrate Transport Amine Transport Transport Vesicle Membrane Serotonin Transport Metal Ion Transport Monoatomic Ion Transmembrane Transport Monoatomic Anion Transmembrane Transport Inorganic Cation Transmembrane Transport
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