TMEM79 and SERP1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		TMEM79	SERP1
Gene Name		transmembrane protein 79	stress-associated endoplasmic reticulum protein 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Integral Component Of Membrane Trans-Golgi Network Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Ribosome Cytoplasmic Microtubule Integral Component Of Membrane
	Molecular Function
	Biological Process	Epithelial Cell Maturation Hair Follicle Morphogenesis Cuticle Development Regulated Secretory Pathway Positive Regulation Of Epidermis Development Establishment Of Skin Barrier Cornification	Skeletal System Development Glucose Metabolic Process Cellular Protein Modification Process Protein Glycosylation Response To Stress Activation Of Signaling Protein Activity Involved In Unfolded Protein Response Plasma Membrane Organization Post-embryonic Development Multicellular Organismal Aging Protein Transport Endoplasmic Reticulum Unfolded Protein Response Positive Regulation Of Insulin Secretion Cellular Protein Metabolic Process Positive Regulation Of Translation Positive Regulation Of Organ Growth Muscle Organ Morphogenesis Positive Regulation Of Growth Hormone Secretion
Pathways			IRE1alpha activates chaperones XBP1(S) activates chaperone genes Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS		mean corpuscular hemoglobin concentration ( 20139978)
Protein-Protein Interactions		14 interactors: ABO CLEC7A PLN PLP2 RNF8 RPRM SEC22A SERP1 SFTPC SLN TEX264 TMEM100 TMPRSS4 TNMD	7 interactors: APP CANX SCNN1A SCNN1G SEC61A1 SEC61B TMEM79
Entrez ID		84283	27230
HPRD ID		17481	18037
Ensembl ID		ENSG00000163472	ENSG00000120742
Uniprot IDs		Q9BSE2	Q9Y6X1
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Calcium Ion Binding Regulation Of Calcium-transporting ATPase Activity Negative Regulation Of Calcium Ion Import Regulation Of Relaxation Of Muscle Negative Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Calcium Ion Import Cellular Response To BMP Stimulus Response To Organic Substance Negative Regulation Of Transporter Activity Regulation Of ATPase Activity Negative Regulation Of Calcium Ion Transport Negative Regulation Of Ion Transmembrane Transport Negative Regulation Of Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Negative Regulation Of Calcium-transporting ATPase Activity Endothelial Cell Differentiation Histone H2A K63-linked Ubiquitination Regulation Of The Force Of Heart Contraction By Cardiac Conduction Endothelium Development Negative Regulation Of Ion Transport Negative Regulation Of Binding Carbohydrate Mediated Signaling Adrenergic Receptor Signaling Pathway Involved In Heart Process G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Cellular Response To Organic Substance Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Tendon Formation Tendon Cell Differentiation Regulation Of Relaxation Of Cardiac Muscle Response To Growth Factor Positive Regulation Of Growth Hormone Secretion Response To Carbohydrate Negative Regulation Of ATPase Activity Tendon Development Vesicle Fusion With Golgi Apparatus Regulation Of Cardiac Muscle Cell Membrane Potential Histone H2B Ubiquitination Regulation Of Calcium Ion Transport Arterial Endothelial Cell Differentiation Interstrand Cross-link Repair Regulation Of Growth Hormone Secretion Negative Regulation Of Heart Rate Sarcoplasmic Reticulum Calcium Ion Transport Blood Vessel Endothelial Cell Differentiation	Multicellular Organismal Water Homeostasis Water Homeostasis Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Body Fluid Levels Transport Sodium Ion Homeostasis Antigen Processing And Presentation Of Peptide Antigen Chemical Homeostasis Antigen Processing And Presentation Excretion Establishment Of Localization In Cell Sensory Perception Of Taste Cellular Localization Metal Ion Homeostasis Secretion By Cell SRP-dependent Cotranslational Protein Targeting To Membrane Homeostatic Process Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Ion Homeostasis Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Protein Localization To Endoplasmic Reticulum Synaptic Growth At Neuromuscular Junction Secretion Cell Maturation Cell Growth Collateral Sprouting In Absence Of Injury Cuticle Development Protein Targeting To Membrane Cornification Collateral Sprouting Axon Midline Choice Point Recognition Retrograde Protein Transport, ER To Cytosol Sodium Ion Transmembrane Transport Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Immune System Process Axon Choice Point Recognition Establishment Of Protein Localization To Membrane Posttranslational Protein Targeting To Membrane Sodium Ion Transport Neuron Remodeling Neurological System Process Exocytosis Establishment Of Protein Localization To Organelle Protein Localization To Membrane Establishment Of Skin Barrier Cellular Copper Ion Homeostasis Regulation Of Water Loss Via Skin
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