TMEM79 and SLN

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		TMEM79	SLN
Description		transmembrane protein 79	sarcolipin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Golgi Apparatus Membrane Trans-Golgi Network Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Enzyme Inhibitor Activity Protein Binding Enzyme Regulator Activity ATPase Binding
	Biological Process	Epithelial Cell Maturation Hair Follicle Morphogenesis Cuticle Development Regulated Exocytosis Positive Regulation Of Epidermis Development Establishment Of Skin Barrier Cornification	Calcium Ion Transport Negative Regulation Of Protein-containing Complex Disassembly Regulation Of Calcium Ion Transport Sarcoplasmic Reticulum Calcium Ion Transport Negative Regulation Of Calcium Ion Import Positive Regulation Of Cold-induced Thermogenesis Regulation Of Relaxation Of Muscle Positive Regulation Of Protein Depolymerization Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum
Pathways			Ion homeostasis Ion transport by P-type ATPases
Drugs
Diseases
GWAS		Glycated hemoglobin levels ( 24647736 28898252 29170429) Mean corpuscular hemoglobin concentration ( 20139978)
Interacting Genes		36 interacting genes: ABO AMIGO1 ANKRD46 APOD ARL13B BRICD5 CLEC7A COQ9 CPLX4 CYB5R3 FAM209A FNDC9 GIMAP1 GPRC5D LDLRAD1 LPAR3 PELI2 PLN PLP2 PVR RNF8 RPRM SEC22A SERP1 SFTPC SLN TEX264 TMEM100 TMEM14C TMEM254 TMEM97 TMPRSS2 TMPRSS4 TNMD TRAM1L1 ZCCHC12	7 interacting genes: ATP2A1 KASH5 LMNA PLN PTPN11 SYNE4 TMEM79
Entrez ID		84283	6588
HPRD ID		17481	03729
Ensembl ID		ENSG00000163472	ENSG00000170290
Uniprot IDs		Q9BSE2	A0A158RFT9 O00631
PDB IDs			1JDM
Enriched GO Terms of Interacting Partners?		Membrane Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Endoplasmic Reticulum Endoplasmic Reticulum Membrane Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Negative Regulation Of Intracellular Transport Negative Regulation Of ATP-dependent Activity Negative Regulation Of Calcium Ion Import Positive Regulation Of Viral Entry Into Host Cell Regulation Of Relaxation Of Muscle	Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Meiotic Nuclear Membrane Microtubule Tethering Complex Relaxation Of Muscle Regulation Of Cardiac Muscle Cell Contraction Regulation Of ATP-dependent Activity Regulation Of System Process Nuclear Envelope Nuclear Outer Membrane Sarcoplasmic Reticulum Membrane Regulation Of Muscle System Process Regulation Of Intracellular Transport Maintenance Of Mitochondrion Location Calcium-dependent ATPase Activity Sarcoplasmic Reticulum Regulation Of Transmembrane Transporter Activity Positive Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Relaxation Of Skeletal Muscle H Zone Regulation Of Cardiac Muscle Contraction Positive Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Positive Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Positive Regulation Of Fast-twitch Skeletal Muscle Fiber Contraction Positive Regulation Of Cardiac Muscle Cell Contraction Regulation Of Striated Muscle Contraction Regulation Of Monoatomic Ion Transmembrane Transporter Activity DNA Double-strand Break Attachment To Nuclear Envelope Chromosome Localization Structural Constituent Of Nuclear Lamina Regulation Of The Force Of Heart Contraction By Cardiac Conduction Calcium Ion-transporting ATPase Complex Negative Regulation Of Calcium Ion Import Into Sarcoplasmic Reticulum Circadian Sleep/wake Cycle, Sleep Phospholamban Complex Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Involved In Heart Process Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Intestinal Epithelial Cell Migration Meiotic Spindle Pole Organelle Localization Developmental Process Negative Regulation Of Multicellular Organismal Process Calcium Ion Import Into Sarcoplasmic Reticulum Regulation Of Cellular Localization Negative Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Cerebellar Cortex Formation Cuticle Development Establishment Or Maintenance Of Microtubule Cytoskeleton Polarity Circadian Sleep/wake Cycle Process Negative Regulation Of Glucocorticoid Secretion Anterior Head Development
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