RAB22A and RABAC1

Number of citations of the paper that reports this interaction (PubMedID 10329441)
0

Data Source:
HPRD (two hybrid)

		RAB22A	RABAC1
Description		RAB22A, member RAS oncogene family	Rab acceptor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Endosome Early Endosome Late Endosome Golgi Apparatus Plasma Membrane Endosome Membrane Endomembrane System Actin Cytoskeleton Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Cell Projection Phagocytic Vesicle Extracellular Exosome	Cytoplasm Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Synapse Presynapse Glutamatergic Synapse
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding GDP Binding	Protein Binding Identical Protein Binding GTPase Binding Proline-rich Region Binding
	Biological Process	Intracellular Protein Transport Endocytosis Endosome Organization Protein Transport Regulation Of Vesicle Size
Pathways		RAB geranylgeranylation
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) Childhood asthma exacerbations in long-acting beta2-agonist treatment ( 33706416) Metabolite levels ( 23823483) Nickel levels ( 26025379)	Brain morphology (MOSTest) ( 32665545) Left-handedness ( 32989287)
Interacting Genes		7 interacting genes: ALS2CL APPL2 EEA1 RAB3GAP1 RAB7A RABAC1 SMURF2	98 interacting genes: ABHD4 AQP6 C6orf47 CMTM3 COQ8A CRB3 CREB3 CYB5R3 CYBRD1 DUSP12 EI24 EMP1 F11R FHIP1B FXR1 FXR2 GDI1 GPR152 HRAS HRG HSD17B13 LEMD3 LMNA LNX1 LTBR MAD2L1 MCF2L MIEF2 NAT14 NDRG2 NDRG4 NIF3L1 NR3C2 NTAQ1 NUDT18 PBX3 PLEKHF2 PLK1 RAB17 RAB1A RAB22A RAB33A RAB3A RAB4A RAB4B RAB5A RAB5B RAB5C RAB6A RAB7A RAP1A RASD2 REEP2 REEP5 RETREG3 RGS2 RHEB RHOA RIC8A RIMS2 RIN3 RNF5 RPS20 RRAS2 S100B SGK1 SH3GL3 SH3GLB1 SLAMF6 SLC10A1 SLC18A1 SNCA SNX1 SNX10 SNX11 SNX15 SNX17 SNX8 SPG21 SSR3 STIM1 STOML2 SYT16 TMEM115 TMEM14B TMEM42 TMX2 TNIP1 TRIM32 TSHR TUBB2A TXN2 UBE2I VAMP2 VIM VTA1 WIPI2 ZFYVE21
Entrez ID		57403	10567
HPRD ID		06696	05375
Ensembl ID		ENSG00000124209	ENSG00000105404
Uniprot IDs		Q9UL26	Q9UI14
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasmic Vesicle Presynaptic Endosome Bounding Membrane Of Organelle Early Endosome To Late Endosome Transport Cellular Localization Endosomal Transport Small GTPase Binding Establishment Of Protein Localization To Organelle Organelle Membrane Fusion Negative Regulation Of Intralumenal Vesicle Formation Epidermal Growth Factor Catabolic Process Lipid Droplet Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome Vesicle Fusion Phagocytic Vesicle Synaptic Vesicle Recycling Via Endosome Phagocytic Vesicle Membrane Intracellular Transport Axonal Spine Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Positive Regulation Of Macropinocytosis Positive Regulation Of Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Lipophagy Glutamatergic Synapse Organelle Fusion Regulation Of Vesicle-mediated Transport Synaptic Vesicle To Endosome Fusion Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Early Phagosome Membrane Cold Acclimation Negative Regulation Of Exosomal Secretion Membrane Fusion Postsynaptic Early Endosome Chemical Synaptic Transmission, Postsynaptic Positive Regulation Of Protein Lipidation Positive Regulation Of Glutamate Secretion, Neurotransmission Cytoplasm Protein To Membrane Docking Establishment Of Localization In Cell Regulation Of Endosome Organization Regulation Of Endoplasmic Reticulum Tubular Network Organization Regulation Of Glutamate Secretion, Neurotransmission Macropinosome Regulation Of Exocytosis Alveolar Lamellar Body Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Trophoblast Cell Migration Endosome Phagosome Acidification	GTPase Activity GTP Binding GDP Binding Membrane Endosome G Protein Activity Establishment Of Localization In Cell Vesicle-mediated Transport Protein Transport Intracellular Protein Localization Establishment Of Protein Localization Cellular Localization Intracellular Protein Transport Protein Binding Endosomal Transport Regulation Of Neuronal Synaptic Plasticity Lipid Binding Secretory Granule Membrane Intracellular Transport Phosphatidylinositol Binding Endocytosis Vesicle Organization Regulation Of Long-term Neuronal Synaptic Plasticity Early Endosome Regulation Of Cellular Component Organization Endosome Organization Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport In Synapse Synaptic Vesicle Exocytosis Localization Within Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Rab Protein Signal Transduction Import Into Cell Early Endosome To Golgi Transport Early Endosome Membrane Endomembrane System Cytoplasmic Vesicle Endoplasmic Reticulum Membrane Organelle Organization Synaptic Vesicle Membrane Identical Protein Binding Autophagosome Assembly Plasma Membrane To Endosome Transport Small GTPase-mediated Signal Transduction Regulation Of Synaptic Plasticity Establishment Of Organelle Localization Autophagosome Organization Endosome Membrane Endocytic Vesicle Organelle Localization
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