PCGF5

Description		polycomb group ring finger 5
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GO Annotations	Cellular Component	X Chromosome Nucleus Nucleoplasm Golgi Apparatus Centrosome PcG Protein Complex PRC1 Complex
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Histone H2AK119 Ubiquitin Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Random Inactivation Of X Chromosome
Pathways		RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Adult body size ( 32376654) Appendicular lean mass ( 33097823) Chronotype ( 30696823) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		9 interacting genes: CBX7 CBX8 DHX57 PRMT6 QKI TRAF2 TRIM8 UBE2D3 USP10
Entrez ID		84333
HPRD ID		17825
Ensembl ID		ENSG00000180628
Uniprot IDs		Q86SE9
PDB IDs		4S3O
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Metabolic Process PRC1 Complex Regulation Of Metabolic Process PcG Protein Complex Stress Granule Assembly Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Ubiquitination Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process Post-translational Protein Modification Protein Polyubiquitination TORC2 Complex Disassembly Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of RNA Metabolic Process MRNA Stabilization Cellular Response To Stress Negative Regulation Of Macromolecule Metabolic Process Protein Modification By Small Protein Conjugation Protein Autoubiquitination Regulation Of Canonical NF-kappaB Signal Transduction Protein Monoubiquitination Chromatin Organization Internal N(7)-methylguanine-containing RNA Reader Activity Histone H2AR3 Methyltransferase Activity Ubiquitin Protein Ligase Activity Regulation Of Macromolecule Metabolic Process Protein K63-linked Ubiquitination Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Catabolic Process Negative Regulation Of Metabolic Process TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Stress Granule Assembly Myofibroblast Contraction Negative Regulation Of MiRNA Catabolic Process Histone H3R2 Methyltransferase Activity Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Metabolic Process Histone Arginine N-methyltransferase Activity Response To Stress Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex DNA Repair
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