PTGER1

Description		prostaglandin E receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	G Protein-coupled Receptor Activity Prostaglandin Receptor Activity Prostaglandin E Receptor Activity D1 Dopamine Receptor Binding
	Biological Process	Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway Response To Lipopolysaccharide Response To Prostaglandin E
Pathways		Prostanoid ligand receptors G alpha (q) signalling events
Drugs		Bupivacaine Carboprost tromethamine Alprostadil Bimatoprost Dinoprostone Misoprostol Iloprost Trichostatin A Limaprost Omidenepag isopropyl Rivenprost
Diseases
GWAS
Interacting Genes		5 interacting genes: ADRB2 PTGDS PTGER3 PTGES PTGFR
Entrez ID		5731
HPRD ID		08903
Ensembl ID		ENSG00000160951
Uniprot IDs		P34995
PDB IDs
Enriched GO Terms of Interacting Partners?		Prostaglandin-D Synthase Activity Regulation Of Fever Generation Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Prostaglandin Biosynthetic Process Prostanoid Biosynthetic Process Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Prostaglandin Metabolic Process Prostanoid Metabolic Process Unsaturated Fatty Acid Biosynthetic Process Icosanoid Biosynthetic Process Regulation Of Acute Inflammatory Response G Protein-coupled Receptor Activity Smooth Muscle Contraction Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Unsaturated Fatty Acid Metabolic Process Prostaglandin F Receptor Activity Icosanoid Metabolic Process Fatty Acid Biosynthetic Process Beta2-adrenergic Receptor Activity Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Beta-adrenergic Receptor Activity Isomerase Activity Negative Regulation Of Male Germ Cell Proliferation Positive Regulation Of Cytosolic Calcium Ion Concentration Prostaglandin-E Synthase Activity Norepinephrine Binding Negative Regulation Of Gastric Acid Secretion Prostaglandin Receptor Activity Intestine Smooth Muscle Contraction Response To Psychosocial Stress Muscle Contraction Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway Regulation Of Male Germ Cell Proliferation Prostaglandin E Receptor Activity Regulation Of Germ Cell Proliferation Positive Regulation Of Fever Generation Cellular Response To Prostaglandin D Stimulus Muscle System Process Positive Regulation Of Autophagosome Maturation Heat Generation Carboxylic Acid Biosynthetic Process Regulation Of Gastric Acid Secretion Adrenergic Receptor Activity Parturition Diet Induced Thermogenesis Negative Regulation Of Multicellular Organismal Process Retinoid Binding
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