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PTGER1
Gene Name
prostaglandin E receptor 1 (subtype EP1), 42kDa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Plasma Membrane
Integral Component Of Plasma Membrane
Molecular Function
Prostaglandin E Receptor Activity
Biological Process
G-protein Coupled Receptor Signaling Pathway
Response To Lipopolysaccharide
Pathways
G alpha (q) signalling events
G alpha (q) signalling events
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
Prostanoid ligand receptors
GPCR downstream signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Class A/1 (Rhodopsin-like receptors)
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Eicosanoid ligand-binding receptors
Drugs
Bupivacaine
Carboprost Tromethamine
Alprostadil
Bimatoprost
Dinoprostone
Iloprost
Diseases
GWAS
Protein-protein Interactions
5 interactors:
ADRB2
PTGDS
PTGER3
PTGES
PTGFR
Entrez ID
5731
HPRD ID
08903
Ensembl ID
ENSG00000160951
Uniprot IDs
P34995
PDB IDs
Enriched GO Terms of Interacting Partners
?
Heat Generation
Cyclooxygenase Pathway
Response To Lipid
Prostaglandin Biosynthetic Process
Temperature Homeostasis
Prostaglandin Metabolic Process
Response To Lipopolysaccharide
Response To Molecule Of Bacterial Origin
Icosanoid Biosynthetic Process
Unsaturated Fatty Acid Biosynthetic Process
Arachidonic Acid Metabolic Process
Response To Bacterium
Acute Inflammatory Response
Icosanoid Metabolic Process
Response To External Stimulus
Unsaturated Fatty Acid Metabolic Process
Long-chain Fatty Acid Metabolic Process
Response To Other Organism
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Response To Biotic Stimulus
Fatty Acid Biosynthetic Process
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway By Arrestin
Vasodilation By Norepinephrine-epinephrine Involved In Regulation Of Systemic Arterial Blood Pressure
Response To Organic Substance
Fever Generation
Multicellular Organismal Homeostasis
G-protein Coupled Receptor Signaling Pathway
Cellular Response To Prostaglandin D Stimulus
Diet Induced Thermogenesis
Fatty Acid Metabolic Process
Positive Regulation Of Fever Generation
Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity
Regulation Of Fever Generation
Positive Regulation Of Heat Generation
Calcium-mediated Signaling Using Intracellular Calcium Source
Chronic Inflammatory Response
Inflammatory Response
Negative Regulation Of Smooth Muscle Contraction
Positive Regulation Of Urine Volume
Adrenergic Receptor Signaling Pathway
Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway
Regulation Of Circadian Sleep/wake Cycle, Sleep
Response To Dietary Excess
Parturition
Cellular Response To Prostaglandin Stimulus
Negative Regulation Of Multicellular Organism Growth
Negative Regulation Of Muscle Contraction
Negative Regulation Of Systemic Arterial Blood Pressure
Response To Stimulus
Tagcloud
?
acutely
autacoids
bdkrb2
bks
blots
butaprost
composing
counterpart
cyclooxygenases
deferens
epididymal
epithelia
hoe140
lining
lysylbradykinin
prostaglandin
prostaglandins
ptgs
ptgs1
ptgs2
ptgss
pvd9902
reportedly
sc
sulprostone
vas