MKLN1 and PTGER3

Number of citations of the paper that reports this interaction (PMID 11006128)
4

Data Source:
BioGRID (pull down)

		MKLN1	PTGER3
Gene Name		muskelin 1, intracellular mediator containing kelch motifs	prostaglandin E receptor 3 (subtype EP3)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytosol Cell Cortex	Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function		Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Prostaglandin E Receptor Activity
	Biological Process	Cell-matrix Adhesion Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Reorganization	Fever Generation Transcription, DNA-templated G-protein Coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Bicarbonate Transport Intracellular Receptor Signaling Pathway Positive Regulation Of Fever Generation Response To Lipopolysaccharide Positive Regulation Of Urine Volume
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR Prostanoid ligand receptors GPCR downstream signaling Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding Eicosanoid ligand-binding receptors
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: GID8 PTGER3 RANBP9	23 interactors: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NL PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42
Entrez ID		4289	5733
HPRD ID		16129	08906
Ensembl ID		ENSG00000128585	ENSG00000050628
Uniprot IDs		B4DG30 Q9UL63	B1AK19 O00325 P43115
PDB IDs
Enriched GO Terms of Interacting Partners?		Fever Generation Heat Generation Positive Regulation Of Fever Generation Regulation Of Fever Generation Positive Regulation Of Heat Generation Positive Regulation Of Urine Volume Microtubule Nucleation Temperature Homeostasis Microtubule Polymerization Positive Regulation Of Acute Inflammatory Response Bicarbonate Transport Acute-phase Response Microtubule Polymerization Or Depolymerization	Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Tagcloud ?		6q arid1a arid1b bclaf1 btg1 clarified cna cnas constituted corresponded cxcr4 deletions delineated foxp1 germline hivep2 hypogammaglobulinemia l265p losses lyn macroglobulinemia myd88 myelokathexis plekhg1 prdm2 recurring waldenstrom wgs wm	accepted acei bdkrb2 cessation combinations converting cough cpn1 digenic epistatic haplotypes hypertensive kinins mme modify monogenic peptidases polymorphisms prostaglandin prostaglandins ptgir ptgis rs11209716 rs2016848 rs4344 rs8012552 substance unresolved xpnpep1
Tagcloud (Difference) ?		6q arid1a arid1b bclaf1 btg1 clarified cna cnas constituted corresponded cxcr4 deletions delineated foxp1 germline hivep2 hypogammaglobulinemia l265p losses lyn macroglobulinemia myd88 myelokathexis plekhg1 prdm2 recurring waldenstrom wgs wm	accepted acei bdkrb2 cessation combinations converting cough cpn1 digenic epistatic haplotypes hypertensive kinins mme modify monogenic peptidases polymorphisms prostaglandin prostaglandins ptgir ptgis rs11209716 rs2016848 rs4344 rs8012552 substance unresolved xpnpep1
Tagcloud (Intersection) ?