MKLN1 and RANBP9

Number of citations of the paper that reports this interaction (PMID 17467196)
20

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, two hybrid, affinity chromatography technology)

		MKLN1	RANBP9
Gene Name		muskelin 1, intracellular mediator containing kelch motifs	RAN binding protein 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Cytosol Cell Cortex	Nucleus Cytosol Microtubule Associated Complex
	Molecular Function		Protein Binding Ran GTPase Binding Enzyme Binding
	Biological Process	Cell-matrix Adhesion Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Reorganization	Protein Complex Assembly Microtubule Nucleation Axon Guidance
Pathways			Axon guidance L1CAM interactions
Drugs
Diseases
GWAS			Breast cancer ( 23535729)
Protein-Protein Interactions		3 interactors: GID8 PTGER3 RANBP9	51 interactors: ADAP1 ADAP2 APC AR AXL BACE1 BRCA1 CACNA1G CALB1 CBS CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM MAPK6 MET MKLN1 MPHOSPH8 NCOA6 NCOR2 OPRM1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1
Entrez ID		4289	10048
HPRD ID		16129	04835
Ensembl ID		ENSG00000128585	ENSG00000010017
Uniprot IDs		B4DG30 Q9UL63	Q96S59
PDB IDs
Enriched GO Terms of Interacting Partners?		Fever Generation Heat Generation Positive Regulation Of Fever Generation Regulation Of Fever Generation Positive Regulation Of Heat Generation Positive Regulation Of Urine Volume Microtubule Nucleation Temperature Homeostasis Microtubule Polymerization Positive Regulation Of Acute Inflammatory Response Bicarbonate Transport Acute-phase Response Microtubule Polymerization Or Depolymerization	Multicellular Organismal Development Anatomical Structure Development Developmental Process System Development Organ Development Response To Organic Substance Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Cell Communication Cellular Response To Organic Substance Signal Transduction Cellular Response To Organic Cyclic Compound Signaling DNA-templated Transcription, Initiation Cellular Response To Stimulus Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Intracellular Receptor Signaling Pathway Regulation Of Signaling Positive Regulation Of Metabolic Process Anatomical Structure Morphogenesis Response To Stimulus Response To Organic Cyclic Compound Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Tissue Development Response To Lipid Nervous System Development Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Steroid Hormone Mediated Signaling Pathway Response To Growth Factor Epithelium Development Wound Healing Negative Regulation Of Signal Transduction Regulation Of Cell Proliferation Response To Hormone Reproductive Process Regulation Of Intracellular Signal Transduction Apoptotic Process Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Cell Death Positive Regulation Of Intracellular Signal Transduction Hormone-mediated Signaling Pathway Cell Activation Negative Regulation Of Signaling DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Tagcloud ?		6q arid1a arid1b bclaf1 btg1 clarified cna cnas constituted corresponded cxcr4 deletions delineated foxp1 germline hivep2 hypogammaglobulinemia l265p losses lyn macroglobulinemia myd88 myelokathexis plekhg1 prdm2 recurring waldenstrom wgs wm	accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Difference) ?		6q arid1a arid1b bclaf1 btg1 clarified cna cnas constituted corresponded cxcr4 deletions delineated foxp1 germline hivep2 hypogammaglobulinemia l265p losses lyn macroglobulinemia myd88 myelokathexis plekhg1 prdm2 recurring waldenstrom wgs wm	accelerates apdeltae9 brains cortex cortical deficits dendritic density egfp exacerbated hippocampus immunoreactive learning mushroom plaque puncta reductions skills spine spines spinophilin striking synapses thin traces transgenic triple vulnerable wt
Tagcloud (Intersection) ?