PTGDS and PTGER1

Number of citations of the paper that reports this interaction (PubMedID 8253813)
0

Data Source:
HPRD (in vivo)

		PTGDS	PTGER1
Description		prostaglandin D2 synthase	prostaglandin E receptor 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Membrane Nuclear Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Membrane
	Molecular Function	Prostaglandin-D Synthase Activity Retinoid Binding Fatty Acid Binding Protein Binding Isomerase Activity Small Molecule Binding	G Protein-coupled Receptor Activity Prostaglandin Receptor Activity Prostaglandin E Receptor Activity D1 Dopamine Receptor Binding
	Biological Process	Prostaglandin Biosynthetic Process Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Prostaglandin Metabolic Process Gene Expression Mast Cell Degranulation Regulation Of Circadian Sleep/wake Cycle, Sleep Prostanoid Biosynthetic Process Response To Glucocorticoid Negative Regulation Of Male Germ Cell Proliferation	Inflammatory Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Phospholipase C-activating G Protein-coupled Glutamate Receptor Signaling Pathway Response To Lipopolysaccharide Response To Prostaglandin E
Pathways		Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Transcriptional regulation of testis differentiation	Prostanoid ligand receptors G alpha (q) signalling events
Drugs		Vitamin A	Bupivacaine Carboprost tromethamine Alprostadil Bimatoprost Dinoprostone Misoprostol Iloprost Trichostatin A Limaprost Omidenepag isopropyl Rivenprost
Diseases
GWAS		Beta-trace protein levels ( 23328707) Corneal structure ( 23291589) Keratoconus ( 33649486)
Interacting Genes		23 interacting genes: ADRB2 AKT1 ARRB2 ATXN1 BCAT2 CACNA1A CAPN1 CARD10 CYSRT1 EGFR GGA3 HK2 HK3 HSP90AA1 KRTAP10-3 KRTAP10-7 KRTAP12-3 MLH1 PTGER1 PTGER2 PTGFR SHBG UBQLN2	5 interacting genes: ADRB2 PTGDS PTGER3 PTGES PTGFR
Entrez ID		5730	5731
HPRD ID		08904	08903
Ensembl ID		ENSG00000107317	ENSG00000160951
Uniprot IDs		A0A024R8G3 P41222	P34995
PDB IDs		2WWP 3O19 3O22 3O2Y 4IMN 4IMO 4ORR 4ORS 4ORU 4ORW 4ORX 4ORY 4OS0 4OS3 4OS8 5WY9 8HTA
Enriched GO Terms of Interacting Partners?		Regulation Of Macroautophagy Response To Prostaglandin E Cellular Response To Prostaglandin Stimulus Hexokinase Activity Glucokinase Activity Fructokinase Activity Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Maintenance Of Protein Location In Mitochondrion Prostaglandin E Receptor Activity Glutamate Receptor Signaling Pathway Regulation Of Biological Quality Nitric-oxide Synthase Regulator Activity D1 Dopamine Receptor Binding Positive Regulation Of Cytosolic Calcium Ion Concentration Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Catabolic Process Excitatory Postsynaptic Potential D-glucose Binding Catabolic Process Regulation Of Autophagy Regulation Of Protein Catabolic Process Phosphotransferase Activity, Alcohol Group As Acceptor Establishment Of Protein Localization To Mitochondrion Response To UV-A Enzyme Binding Fructose 6-phosphate Metabolic Process Positive Regulation Of Protein Catabolic Process Response To Ketone Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Identical Protein Binding Cellular Response To Prostaglandin E Stimulus Regulation Of Postsynaptic Membrane Potential Response To Alcohol Macromolecule Catabolic Process Negative Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Peptidyl-serine Phosphorylation Glycolytic Process Through Glucose-6-phosphate Carbohydrate Phosphorylation Glucose 6-phosphate Metabolic Process Glycolytic Process Through Fructose-6-phosphate Canonical Glycolysis Keratin Filament Positive Regulation Of DNA Metabolic Process Positive Regulation Of Protein Metabolic Process Ficolin-1-rich Granule Lumen Positive Regulation Of Metabolic Process Glucose Metabolic Process Glucose Catabolic Process Ionotropic Glutamate Receptor Signaling Pathway	Prostaglandin-D Synthase Activity Regulation Of Fever Generation Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Prostaglandin Biosynthetic Process Prostanoid Biosynthetic Process Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Prostaglandin Metabolic Process Prostanoid Metabolic Process Unsaturated Fatty Acid Biosynthetic Process Icosanoid Biosynthetic Process Regulation Of Acute Inflammatory Response G Protein-coupled Receptor Activity Smooth Muscle Contraction Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine Positive Regulation Of Mini Excitatory Postsynaptic Potential Unsaturated Fatty Acid Metabolic Process Prostaglandin F Receptor Activity Icosanoid Metabolic Process Fatty Acid Biosynthetic Process Beta2-adrenergic Receptor Activity Norepinephrine-epinephrine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure G Protein-coupled Receptor Signaling Pathway Beta-adrenergic Receptor Activity Isomerase Activity Negative Regulation Of Male Germ Cell Proliferation Positive Regulation Of Cytosolic Calcium Ion Concentration Prostaglandin-E Synthase Activity Norepinephrine Binding Negative Regulation Of Gastric Acid Secretion Prostaglandin Receptor Activity Intestine Smooth Muscle Contraction Response To Psychosocial Stress Muscle Contraction Positive Regulation Of Lipophagy AMPA Selective Glutamate Receptor Signaling Pathway Regulation Of Male Germ Cell Proliferation Prostaglandin E Receptor Activity Regulation Of Germ Cell Proliferation Positive Regulation Of Fever Generation Cellular Response To Prostaglandin D Stimulus Muscle System Process Positive Regulation Of Autophagosome Maturation Heat Generation Carboxylic Acid Biosynthetic Process Regulation Of Gastric Acid Secretion Adrenergic Receptor Activity Parturition Diet Induced Thermogenesis Negative Regulation Of Multicellular Organismal Process Retinoid Binding
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?