PTGDS and ARR3

Number of citations of the paper that reports this interaction (PMID 21112970)
3

Data Source:
BioGRID (pull down)

		PTGDS	ARR3
Gene Name		prostaglandin D2 synthase 21kDa (brain)	arrestin 3, retinal (X-arrestin)
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Extracellular Space Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Nuclear Membrane Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome	Photoreceptor Outer Segment Photoreceptor Inner Segment Cytoplasm Synapse
	Molecular Function	Prostaglandin-D Synthase Activity Transporter Activity Retinoid Binding Fatty Acid Binding	Opsin Binding Protein Binding Phosphoprotein Binding
	Biological Process	Prostaglandin Biosynthetic Process Transport Arachidonic Acid Metabolic Process Cyclooxygenase Pathway Small Molecule Metabolic Process Regulation Of Circadian Sleep/wake Cycle, Sleep Response To Glucocorticoid	Regulation Of Protein Phosphorylation Endocytosis Signal Transduction Visual Perception
Pathways		Arachidonic acid metabolism Metabolism of lipids and lipoproteins Synthesis of Prostaglandins (PG) and Thromboxanes (TX)
Drugs
Diseases
GWAS		Beta-trace protein levels ( 23328707) Corneal structure ( 23291589)
Protein-Protein Interactions		17 interactors: ARR3 ARRB2 ATXN1 BCAT2 CACNA1A CAPN1 EGFR HK2 HK3 HSP90AA1 KRTAP10-3 KRTAP10-7 MLH1 PTGER1 PTGER2 PTGFR SHBG	23 interactors: ADRB2 AP3B1 CAPNS1 CLTC CSNK2A1 CSNK2A2 CYTH1 DVL2 FSHR GNMT MAP2K7 OPN1MW OPN4 PARK2 PLK4 PTAFR PTGDS RCOR2 RHO RNASE6 SRC ZBTB43 ZNF496
Entrez ID		5730	407
HPRD ID		08904	02358
Ensembl ID		ENSG00000107317	ENSG00000120500
Uniprot IDs		P41222	P36575
PDB IDs		2WWP 3O19 3O22 3O2Y 4IMN 4IMO	1XEH 2A34
Enriched GO Terms of Interacting Partners?		Adult Locomotory Behavior Response To External Stimulus Cellular Response To Prostaglandin Stimulus Adult Behavior Single-organism Behavior Cellular Response To Acid Chemical Glucose 6-phosphate Metabolic Process Regulation Of Nitric-oxide Synthase Activity Hexose Metabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Fatty Acid Locomotory Behavior Response To Abiotic Stimulus Behavior Adult Walking Behavior Monosaccharide Metabolic Process Signaling Catabolic Process G-protein Coupled Receptor Signaling Pathway Neurological System Process Cell Communication Regulation Of Nitric Oxide Biosynthetic Process Carbohydrate Phosphorylation Isoleucine Catabolic Process Alkanesulfonate Metabolic Process Cerebellar Molecular Layer Development Negative Regulation Of Eosinophil Extravasation Meiotic Metaphase I Plate Congression Meiotic Spindle Midzone Assembly Primary Spermatocyte Growth Cell Activation Regulation Of Reactive Oxygen Species Biosynthetic Process Developmental Process Involved In Reproduction Regulation Of Synaptic Transmission Response To Lipopolysaccharide Response To Fatty Acid Reproductive Process Cellular Response To Mechanical Stimulus Glucose Transport Anatomical Structure Development Cellular Glucose Homeostasis Receptor Metabolic Process Positive Regulation Of Protein Kinase B Signaling Response To Molecule Of Bacterial Origin Regulation Of Oxidoreductase Activity Hexose Transport Multicellular Organismal Reproductive Process Branched-chain Amino Acid Biosynthetic Process Vestibular Nucleus Development	Protein-chromophore Linkage Regulation Of Carbohydrate Metabolic Process Response To External Stimulus Regulation Of Cellular Process Cell Surface Receptor Signaling Pathway Phototransduction, Visible Light Detection Of Visible Light Phototransduction Detection Of Light Stimulus Regulation Of Glucose Metabolic Process Regulation Of MAPK Cascade Response To Light Stimulus Positive Regulation Of Organelle Assembly Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Cellular Protein Modification Process Rhodopsin Mediated Signaling Pathway Positive Regulation Of Wnt Signaling Pathway Response To Abiotic Stimulus Cellular Metabolic Process Regulation Of JNK Cascade Bone Resorption G-protein Coupled Receptor Signaling Pathway Visual Perception Detection Of Abiotic Stimulus Sensory Perception Of Light Stimulus Signaling Mitotic Spindle Checkpoint Regulation Of Stress-activated MAPK Cascade Negative Regulation Of Chromosome Segregation Regulation Of Kinase Activity Cell Communication Positive Regulation Of MAPK Cascade Response To Radiation Positive Regulation Of Protein Metabolic Process Positive Regulation Of Intracellular Signal Transduction Regulation Of Proteasomal Protein Catabolic Process Lysosomal Transport Positive Regulation Of Protein Kinase Activity Positive Regulation Of Signal Transduction Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Mitochondrial Fusion Red, Far-red Light Phototransduction Regulation Of Cell Cycle Process Positive Regulation Of MAP Kinase Activity Positive Regulation Of Kinase Activity Cellular Process
Tagcloud ?		11beta 9alpha abcc4 akr1b1 akr1c1 akr1c3 catalyze diseased endometriosis endometriotic endometrium gynecological hieec hiesc hpgd hpgds infertility peritoneal pgd2 pgf2alpha pgh2 pla2g2a pla2g4a provokes ptgfr ptgs2 reaches slco2a synthases	arr2 arrestins arrs distributed gpcr gpcrs grk grk2 grk5 grk6 grks innate macrophages mechanistically modify responsiveness surprisingly talk tlr2 tlr3 tlr4 tlrs toll transcriptionally translational ubiquitously uncover vital
Tagcloud (Difference) ?		11beta 9alpha abcc4 akr1b1 akr1c1 akr1c3 catalyze diseased endometriosis endometriotic endometrium gynecological hieec hiesc hpgd hpgds infertility peritoneal pgd2 pgf2alpha pgh2 pla2g2a pla2g4a provokes ptgfr ptgs2 reaches slco2a synthases	arr2 arrestins arrs distributed gpcr gpcrs grk grk2 grk5 grk6 grks innate macrophages mechanistically modify responsiveness surprisingly talk tlr2 tlr3 tlr4 tlrs toll transcriptionally translational ubiquitously uncover vital
Tagcloud (Intersection) ?