Wiki-Pi
About
Search
People
Updates
Search
ARR3 and PLK4
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
ARR3
PLK4
Description
arrestin 3
polo like kinase 4
Image
No pdb structure
GO Annotations
Cellular Component
Photoreceptor Outer Segment
Photoreceptor Inner Segment
Cytoplasm
Cell Projection
Synapse
XY Body
Nucleus
Nucleolus
Cytoplasm
Centrosome
Centriole
Cytosol
Cytoskeleton
Cleavage Furrow
Deuterosome
Procentriole
Procentriole Replication Complex
Molecular Function
G Protein-coupled Receptor Binding
Opsin Binding
Protein Binding
Phosphoprotein Binding
Nucleotide Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Kinase Activity
Transferase Activity
Identical Protein Binding
Protein Serine Kinase Activity
Biological Process
G Protein-coupled Receptor Internalization
Endocytosis
Signal Transduction
Visual Perception
Protein Phosphorylation
Centriole Replication
Regulation Of Cell Cycle Process
Positive Regulation Of Centriole Replication
Cilium Assembly
Trophoblast Giant Cell Differentiation
De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation
Pathways
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2
Drugs
Fostamatinib
Diseases
GWAS
Interacting Genes
20 interacting genes:
ADRB2
AP3B1
CAPNS1
CLTC
CSNK2A1
DVL2
FSHR
GNMT
MAP2K7
MARCHF8
OPN1MW
OPN4
PLK4
PTAFR
RCOR2
RHO
RNASE6
SRC
ZBTB43
ZNF496
25 interacting genes:
ACTR2
AIRIM
ARR3
BTRC
CHD3
CYLD
DCAF1
DNAJB13
DRC4
ELOA
MIR126
MTUS2
OSBPL3
PRDM16
SFN
SMAD4
SPAG5
TAX1BP3
TEC
TENT5B
TENT5C
TFIP11
TGFBR1
TRIM54
ZBTB39
Entrez ID
407
10733
HPRD ID
02358
10387
Ensembl ID
ENSG00000120500
ENSG00000142731
Uniprot IDs
P36575
O00444
PDB IDs
2N19
3COK
4JXF
4N7V
4N7Z
4N9J
4YUR
4YYP
5LHY
5LHZ
6N45
6N46
6W38
6W3I
6W3J
8XPG
Enriched GO Terms of Interacting Partners
?
Photoreceptor Activity
G Protein-coupled Photoreceptor Activity
Thermotaxis
Photoreceptor Disc Membrane
G Protein-coupled Receptor Activity
Detection Of Visible Light
Sperm Head Plasma Membrane
Absorption Of Visible Light
Phototransduction
Detection Of Temperature Stimulus Involved In Thermoception
11-cis Retinal Binding
G Protein-coupled Receptor Signaling Pathway
Response To Temperature Stimulus
Detection Of Light Stimulus
Positive Regulation Of MAPK Cascade
Lysosome
Transcytosis
Regulation Of Organelle Organization
Cellular Response To Light Stimulus
Detection Of Temperature Stimulus Involved In Sensory Perception
Uterus Development
Clathrin-coated Endocytic Vesicle
Detection Of Temperature Stimulus
Bone Resorption
Detection Of Abiotic Stimulus
Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway
Response To Light Stimulus
Enzyme Binding
Regulation Of Systemic Arterial Blood Pressure By Norepinephrine-epinephrine
Vacuolar Transport
Regulation Of Systemic Arterial Blood Pressure
Regulation Of MAPK Cascade
Positive Regulation Of Mini Excitatory Postsynaptic Potential
Regulation Of Bone Remodeling
Regulation Of Bone Resorption
Follicle-stimulating Hormone Receptor Activity
Regulation Of Acetylcholine Metabolic Process
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Cellular Response To Radiation
Rod Bipolar Cell Differentiation
RNA Polymerase III General Transcription Initiation Factor Binding
Glycine N-methyltransferase Activity
Positive Regulation Of ERK1 And ERK2 Cascade
Visual Perception
Sensory Perception Of Light Stimulus
Regulation Of Macroautophagy
Response To Radiation
Protein Targeting To Vacuole
Vasodilation
Fc Receptor Signaling Pathway
Cytoplasm
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Centrosome
Cytoskeleton
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Microtubule
Negative Regulation Of Cell Population Proliferation
Positive Regulation Of Extracellular Matrix Assembly
Endothelial Cell Activation
Poly(A) RNA Polymerase Activity
Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Metabolic Process
I-SMAD Binding
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of RNA Metabolic Process
Positive Regulation Of T Cell Receptor Signaling Pathway
Microtubule Binding
Regulation Of Extracellular Matrix Assembly
Positive Regulation Of Antigen Receptor-mediated Signaling Pathway
Positive Regulation Of Extracellular Matrix Organization
Microtubule-based Process
Regulation Of Cytoskeleton Organization
Activin Receptor Signaling Pathway
Cardiac Epithelial To Mesenchymal Transition
Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Centriolar Satellite
Regulation Of Primary Metabolic Process
Ciliary Basal Body
Phosphoprotein Binding
Negative Regulation Of Interleukin-18-mediated Signaling Pathway
Regulation Of Wnt Signaling Pathway
Met1-linked Polyubiquitin Deubiquitinase Activity
Negative Regulation Of Epithelial Cell Proliferation
Negative Regulation Of Cardiac Myofibril Assembly
Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis
Female Gonad Morphogenesis
Histone H2AT120 Kinase Activity
Cell Competition In A Multicellular Organism
Neuron Fate Commitment
Ventricular Septum Morphogenesis
Nucleus
Regulation Of Microtubule Cytoskeleton Organization
Positive Regulation Of SMAD Protein Signal Transduction
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of Wnt Signaling Pathway
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?