Wiki-Pi
About
Search
People
Updates
Search
BAG1 and PYGL
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
BAG1
PYGL
Description
BAG cochaperone 1
glycogen phosphorylase L
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Extracellular Region
Cytoplasm
Cytosol
Secretory Granule Lumen
Extracellular Exosome
Ficolin-1-rich Granule Lumen
Molecular Function
Adenyl-nucleotide Exchange Factor Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Protein-folding Chaperone Binding
Nucleotide Binding
Purine Nucleobase Binding
Catalytic Activity
1,4-alpha-oligoglucan Phosphorylase Activity
Protein Binding
ATP Binding
D-glucose Binding
Glycogen Phosphorylase Activity
AMP Binding
Transferase Activity
Glycosyltransferase Activity
Vitamin Binding
Pyridoxal Phosphate Binding
Bile Acid Binding
Identical Protein Binding
Biological Process
Protein Folding
Apoptotic Process
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Smooth Muscle Cell Apoptotic Process
Negative Regulation Of Apoptotic Process
Protein Stabilization
Carbohydrate Metabolic Process
Glycogen Metabolic Process
Glycogen Catabolic Process
Response To Bacterium
Glucose Homeostasis
Necroptotic Process
Pathways
Regulation of HSF1-mediated heat shock response
Neutrophil degranulation
Glycogen breakdown (glycogenolysis)
Drugs
(2R,3R,4S,5R)-2-[6-amino-8-[(3,4-dichlorophenyl)methylamino]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
Diseases
Glycogen storage diseases (GSD), including: von Gierke disease (GSD type Ia); Pompe disease (GSD type II); Cori disease, Forbe disease (GSD type III); Andersen disease (GSD type IV); McArdle disease (GSD type V); Hers disease (GSD type VI); Tarui disease (GSD type VII); Phosphorylase kinase deficiency (GSD type IX); Fanconi-Bickel syndrome (GSD type XI); Glycogen synthase deficiency (GSD type 0)
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Acute lymphoblastic leukemia (childhood) (
23007406
)
Blood protein levels (
30072576
)
Psychosis (atypical) (
24132900
)
Rectal cancer (
33632709
)
Interacting Genes
31 interacting genes:
AR
ARRB1
BCL2
BCL2L1
CEBPA
ESR1
HBEGF
HSPA1A
HSPA1B
HSPA4
HSPA8
LRRK1
LRRK2
MAPT
MET
NR3C1
OGT
PDGFRB
PPP1R15A
PSMD1
PSMD2
PYGL
RAF1
RARA
RB1
SIAH1
STUB1
TRIM23
TRIM27
UBC
VDR
7 interacting genes:
BAG1
CEBPA
HSD17B10
HSD3B7
IDH2
PYGB
PYGM
Entrez ID
573
5836
HPRD ID
03292
01987
Ensembl ID
ENSG00000107262
ENSG00000100504
Uniprot IDs
A0A0S2Z3K4
Q99933
P06737
PDB IDs
1HX1
1WXV
3FZF
3FZH
3FZK
3FZL
3FZM
3LDQ
3M3Z
5AQF
5AQG
5AQH
5AQI
5AQJ
5AQK
5AQL
5AQM
5AQN
5AQO
5AQP
5AQQ
5AQR
5AQS
5AQT
5AQU
5AQV
1EM6
1EXV
1FA9
1FC0
1L5Q
1L5R
1L5S
1L7X
1XOI
2ATI
2QLL
2ZB2
3CEH
3CEJ
3CEM
3DD1
3DDS
3DDW
8EMS
Enriched GO Terms of Interacting Partners
?
Enzyme Binding
Regulation Of Intracellular Signal Transduction
Regulation Of Protein Metabolic Process
Regulation Of Programmed Cell Death
Regulation Of Cell Communication
Regulation Of Signal Transduction
Regulation Of Signaling
Macromolecule Metabolic Process
Cytosol
Ubiquitin Protein Ligase Binding
Regulation Of Protein-containing Complex Assembly
Negative Regulation Of Signal Transduction
Response To Hormone
Negative Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Cell Communication
Negative Regulation Of Signaling
Intracellular Signal Transduction
Negative Regulation Of Metabolic Process
Regulation Of Apoptotic Signaling Pathway
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of Primary Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of Intracellular Signal Transduction
Nuclear Receptor Activity
Regulation Of Apoptotic Process
C3HC4-type RING Finger Domain Binding
Positive Regulation Of Metabolic Process
Signal Transduction
Response To Steroid Hormone
Identical Protein Binding
Regulation Of Protein Modification Process
ATP-dependent Protein Disaggregase Activity
Cellular Response To Hormone Stimulus
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Apoptotic Process
Regulation Of Cellular Component Organization
G Protein-coupled Receptor Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
Mitochondrion
Regulation Of Protein Catabolic Process
Regulation Of Autophagy
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Cell Population Proliferation
Regulation Of Biological Quality
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Microtubule Polymerization
Cellular Response To Steroid Hormone Stimulus
Glycogen Phosphorylase Activity
1,4-alpha-oligoglucan Phosphorylase Activity
Bile Acid Biosynthetic Process
Polysaccharide Catabolic Process
Glycogen Catabolic Process
Bile Acid Metabolic Process
Steroid Metabolic Process
Generation Of Precursor Metabolites And Energy
RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding
Isoursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity
Chenodeoxycholate 7-alpha-dehydrogenase (NAD+) Activity
3-hydroxy-2-methylbutyryl-CoA Dehydrogenase Activity
Cholate 7-alpha-dehydrogenase (NAD+) Activity
Ursodeoxycholate 7-beta-dehydrogenase (NAD+) Activity
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Glycogen Metabolic Process
Energy Reserve Metabolic Process
Polysaccharide Metabolic Process
Pyridoxal Phosphate Binding
Cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase Activity
Carbohydrate Metabolic Process
Response To Vitamin B2
C/EBP Complex
17-beta-hydroxysteroid Dehydrogenase (NAD+) Activity
Brexanolone Metabolic Process
Glyoxylate Cycle
Isocitrate Dehydrogenase (NADP+) Activity
Monocarboxylic Acid Metabolic Process
CHOP-C/EBP Complex
Mitochondrial Ribonuclease P Complex
Mitochondrial TRNA 5'-end Processing
Mitochondrial TRNA 3'-end Processing
Mitochondrial TRNA Methylation
Carbohydrate Catabolic Process
3-beta-hydroxy-Delta5-steroid Dehydrogenase (NAD+) Activity
Oxidoreductase Activity
White Fat Cell Proliferation
Mitochondrial RNA 5'-end Processing
Negative Regulation Of Hematopoietic Stem Cell Proliferation
Rb-E2F Complex
Isoleucine Metabolic Process
L-isoleucine Catabolic Process
Isocitrate Metabolic Process
Epsilon DNA Polymerase Complex
B Cell Chemotaxis
Small Molecule Metabolic Process
TRNA Methyltransferase Complex
Mitochondrial RNA 3'-end Processing
Testosterone Dehydrogenase (NAD+) Activity
(3S)-3-hydroxyacyl-CoA Dehydrogenase (NAD+) Activity
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?