SNRPA and PAPOLA

Number of citations of the paper that reports this interaction (PMID 10742179)
40

Data Source:
HPRD (in vitro)

		SNRPA	PAPOLA
Gene Name		small nuclear ribonucleoprotein polypeptide A	poly(A) polymerase alpha
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex U1 SnRNP Nucleolus Cytoplasm	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Nucleotide Binding RNA Binding Protein Binding SnRNA Binding Poly(A) RNA Binding	Magnesium Ion Binding RNA Binding Polynucleotide Adenylyltransferase Activity ATP Binding Manganese Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Splicing Gene Expression	MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription RNA Splicing Gene Expression MRNA 3'-end Processing RNA Polyadenylation
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Processing of Capped Intronless Pre-mRNA mRNA Splicing - Major Pathway Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: C19orf43 CDKN2A CIRBP ENOX2 GABPB1 HNRNPK IL7R LENG8 METTL13 MTUS2 NDUFAF3 PAPOLA PCBP1 PCBP2 PTBP1 PTBP2 QKI RBM3 RBM42 RBMX SFPQ SMAD5 SNRPA1 TRIM27 U2AF2 UBC WBP4	6 interactors: CPSF1 CPSF3 RRAGA SMAD2 SNRPA YWHAE
Entrez ID		6626	10914
HPRD ID		01658	10407
Ensembl ID		ENSG00000077312	ENSG00000090060
Uniprot IDs		B4DDC7 P09012	G3XAH6 P51003
PDB IDs		1AUD 1CX0 1DRZ 1DZ5 1FHT 1M5K 1M5O 1M5P 1M5V 1NU4 1OIA 1SJ3 1SJ4 1SJF 1U6B 1URN 1VBX 1VBY 1VBZ 1VC0 1VC5 1VC6 1VC7 1ZZN 2A3J 2NZ4 2OIH 2OJ3 2U1A 3BO2 3BO3 3BO4 3CUL 3CUN 3EGZ 3G8S 3G8T 3G96 3G9C 3HHN 3IIN 3IRW 3IWN 3K0J 3L3C 3MUM 3MUR 3MUT 3MUV 3MXH 3P49 3PGW 3R1H 3R1L 3UCU 3UCZ 3UD3 3UD4 3UTR
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Negative Regulation Of RNA Splicing RNA Metabolic Process Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Positive Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Gene Expression Regulation Of MRNA Processing Negative Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Metabolic Process Macromolecule Biosynthetic Process Regulation Of Alternative MRNA Splicing, Via Spliceosome Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Regulation Of T Cell Differentiation In Thymus Negative Regulation Of Immune System Process Positive Regulation Of Cellular Metabolic Process Protein K63-linked Ubiquitination Positive Regulation Of RNA Splicing Negative Regulation Of Adaptive Immune Response Protein Polyubiquitination Termination Of RNA Polymerase II Transcription Posttranscriptional Regulation Of Gene Expression Negative Regulation Of Type I Interferon Production Biosynthetic Process Ultradian Rhythm Negative Regulation Of Cytokine Production Cellular Metabolic Process Regulation Of MRNA Stability	RNA Processing MRNA Cleavage MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Polyadenylation RNA Polyadenylation Termination Of RNA Polymerase II Transcription RNA Splicing Cellular Localization MRNA Processing MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus MRNA 3'-end Processing MRNA Metabolic Process RNA 3'-end Processing Nuclear Export MRNA Transport Positive Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Negative Regulation Of Peptidyl-serine Dephosphorylation Regulation Of Heart Rate By Hormone RNA Transport RNA Localization Establishment Of Localization In Cell Zygotic Specification Of Dorsal/ventral Axis Regulation Of Nodal Signaling Pathway Involved In Determination Of Lateral Mesoderm Left/right Asymmetry Transcription From RNA Polymerase II Promoter Positive Regulation Of Cytolysis Histone MRNA 3'-end Processing Negative Regulation Of Protein Dephosphorylation Positive Regulation Of Mesoderm Development Primary MiRNA Processing Regulation Of Nodal Signaling Pathway Common-partner SMAD Protein Phosphorylation Nucleocytoplasmic Transport Nuclear Transport Positive Regulation Of Activin Receptor Signaling Pathway Regulation Of Heart Rate By Chemical Signal Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Nucleic Acid Phosphodiester Bond Hydrolysis Positive Regulation Of Signal Transduction SMAD Protein Complex Assembly Membrane Repolarization Paraxial Mesoderm Morphogenesis RNA Metabolic Process Nodal Signaling Pathway Intracellular Transport Gene Expression Histone MRNA Metabolic Process
Tagcloud ?		adh1c aldh6a1 aldob apom ces1 fads1 ftl glo1 hemopexin hnrpdl loc644587 lrrc28 methylglyoxal orosomucoid pabpc1 pla2g10 polr2k rpl14 rpl41 rpl8 rps17 rps24 rps5 srp9 ssh subtractive underexpressed zbtb11 zip14
Tagcloud (Difference) ?		adh1c aldh6a1 aldob apom ces1 fads1 ftl glo1 hemopexin hnrpdl loc644587 lrrc28 methylglyoxal orosomucoid pabpc1 pla2g10 polr2k rpl14 rpl41 rpl8 rps17 rps24 rps5 srp9 ssh subtractive underexpressed zbtb11 zip14
Tagcloud (Intersection) ?