PLXDC1 and NID1

Number of citations of the paper that reports this interaction (PubMedID 16574105)
0

Data Source:
HPRD (in vitro, in vivo)

		PLXDC1	NID1
Description		plexin domain containing 1	nidogen 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Plasma Membrane Bicellular Tight Junction Membrane Dendrite Neuronal Cell Body Receptor Complex Anchoring Junction	Extracellular Region Basement Membrane Extracellular Matrix Extracellular Exosome Cell Periphery Protein Complex Involved In Cell-matrix Adhesion
	Molecular Function	Protein Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Collagen Binding Laminin Binding Laminin-1 Binding Proteoglycan Binding Extracellular Matrix Binding
	Biological Process	Angiogenesis Spinal Cord Development	Cell Adhesion Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization Glomerular Basement Membrane Development Positive Regulation Of Cell Adhesion Positive Regulation Of Muscle Cell Differentiation Basement Membrane Organization Regulation Of Basement Membrane Organization Positive Regulation Of Integrin-mediated Signaling Pathway
Pathways			Degradation of the extracellular matrix Degradation of the extracellular matrix Laminin interactions Laminin interactions
Drugs			Urokinase
Diseases
GWAS		Asthma ( 31619474) Tau burden ( 33426524)	Cutaneous nevi ( 21478494) Diverticulitis ( 28585551) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Mean platelet volume ( 32888494) Response to levetiracetam in genetic generalized epilepsy ( 32308125) Urate levels in overweight individuals ( 25811787)
Interacting Genes		4 interacting genes: C5AR2 GPR35 NID1 NRF1	21 interacting genes: APP COL13A1 COL1A1 COL4A1 FBLN1 FBLN2 FGA FGB HSPG2 ITGAV ITGB3 LACRT LAMA1 LAMC1 LAMC2 LGALS3BP PLAU PLXDC1 PRELP PTPRF SKIL
Entrez ID		57125	4811
HPRD ID		08439	00574
Ensembl ID		ENSG00000161381	ENSG00000116962
Uniprot IDs		Q8IUK5	P14543
PDB IDs
Enriched GO Terms of Interacting Partners?		C-X-C Chemokine Receptor Activity Positive Regulation Of Cytosolic Calcium Ion Concentration Negative Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Basement Membrane Organization Laminin-1 Binding Complement Component C5a Receptor Activity Complement Component C5a Signaling Pathway Negative Regulation Of Neutrophil Migration Complement Receptor Activity Negative Regulation Of Neutrophil Chemotaxis Protein Complex Involved In Cell-matrix Adhesion G Protein-coupled Receptor Activity Positive Regulation Of Integrin-mediated Signaling Pathway Proteoglycan Binding Glomerular Basement Membrane Development Complement Receptor Mediated Signaling Pathway Regulation Of Voltage-gated Calcium Channel Activity Regulation Of Integrin-mediated Signaling Pathway Laminin Binding Negative Regulation Of Leukocyte Chemotaxis Chemokine Receptor Activity Negative Regulation Of Transporter Activity	Extracellular Matrix Structural Constituent Extracellular Matrix Extracellular Region Basement Membrane Extracellular Space Blood Coagulation, Fibrin Clot Formation Regulation Of Cell Adhesion Cell Adhesion Regulation Of Cell-substrate Adhesion Protein Activation Cascade Cell-substrate Adhesion Positive Regulation Of Cell Adhesion Protein Complex Involved In Cell-matrix Adhesion Cell-matrix Adhesion Plasminogen Activation Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Signal Transduction Integrin Binding Regulation Of Substrate Adhesion-dependent Cell Spreading Extracellular Exosome Endoplasmic Reticulum Lumen Heparin Binding Regulation Of Extrinsic Apoptotic Signaling Pathway Integrin Alphav-beta3 Complex Platelet Alpha Granule Fibrinolysis Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Integrin-mediated Signaling Pathway External Side Of Plasma Membrane Positive Regulation Of Cell Migration Extracellular Vesicle Positive Regulation Of Cell Motility Alphav-beta3 Integrin-PKCalpha Complex Alphav-beta3 Integrin-HMGB1 Complex Laminin-1 Complex Cell Adhesion Molecule Binding Positive Regulation Of Locomotion Cell Surface Receptor Signaling Pathway Fibronectin Binding Extracellular Matrix Binding Blood Coagulation Coagulation Alphav-beta3 Integrin-IGF-1-IGF1R Complex Hemostasis Negative Regulation Of Endothelial Cell Apoptotic Process Regulation Of Cell Migration Extracellular Matrix Organization Extracellular Structure Organization Extracellular Matrix Structural Constituent Conferring Tensile Strength
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?