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CCDC47 and IRF7
Number of citations of the paper that reports this interaction (PMID
21903422
)
33
Data Source:
BioGRID
(affinity chromatography technology, pull down)
CCDC47
IRF7
Gene Name
coiled-coil domain containing 47
interferon regulatory factor 7
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum
Membrane
Integral Component Of Membrane
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Endosome Membrane
Molecular Function
Calcium Ion Binding
Protein Binding
Poly(A) RNA Binding
RNA Polymerase II Core Promoter Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity
DNA Binding
Protein Binding
Biological Process
Osteoblast Differentiation
ER Overload Response
Post-embryonic Development
Calcium Ion Homeostasis
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Regulation Of Adaptive Immune Response
Transcription From RNA Polymerase II Promoter
Cellular Response To DNA Damage Stimulus
Response To Virus
Immunoglobulin Mediated Immune Response
Establishment Of Viral Latency
Cytokine-mediated Signaling Pathway
Regulation Of Type I Interferon Production
Positive Regulation Of Type I Interferon Production
Interferon-alpha Production
Interferon-beta Production
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-beta Production
Regulation Of MyD88-dependent Toll-like Receptor Signaling Pathway
Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
MDA-5 Signaling Pathway
Innate Immune Response
Type I Interferon Biosynthetic Process
Regulation Of Monocyte Differentiation
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Immune Response
Interferon-gamma-mediated Signaling Pathway
Type I Interferon Signaling Pathway
Positive Regulation Of Type I Interferon-mediated Signaling Pathway
Negative Regulation Of Macrophage Apoptotic Process
Pathways
TRIF-mediated TLR3/TLR4 signaling
Cytosolic sensors of pathogen-associated DNA
Toll Like Receptor 7/8 (TLR7/8) Cascade
Interferon Signaling
Cytokine Signaling in Immune system
Factors involved in megakaryocyte development and platelet production
MyD88-independent cascade
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
Interferon gamma signaling
Activated TLR4 signalling
TRAF3-dependent IRF activation pathway
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Toll-Like Receptors Cascades
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor 3 (TLR3) Cascade
MyD88 dependent cascade initiated on endosome
TRAF6 mediated IRF7 activation
Interferon alpha/beta signaling
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
Toll Like Receptor 9 (TLR9) Cascade
Innate Immune System
Drugs
Diseases
GWAS
Systemic lupus erythematosus and Systemic sclerosis (
23740937
)
Protein-Protein Interactions
7 interactors:
IRAK1
IRF7
RPL7A
SARM1
TIRAP
TMEM173
TOM1L1
25 interactors:
ACADS
AIP
ARAF
CCDC47
CREBBP
EP300
GCLM
INSR
IRAK1
IRF3
KAT2A
KAT2B
LTN1
MAVS
MYD88
PALD1
PIAS4
TBK1
TICAM1
TICAM2
TLK2
TP53
TRAF6
TRIM28
TRMT61B
Entrez ID
57003
3665
HPRD ID
17041
05441
Ensembl ID
ENSG00000108588
ENSG00000185507
Uniprot IDs
Q96A33
M9RSF4
Q92985
PDB IDs
2O61
Enriched GO Terms of Interacting Partners
?
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Regulation Of Innate Immune Response
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Interferon-beta Production
Positive Regulation Of Immune Response
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Innate Immune Response
Regulation Of Immune Response
Positive Regulation Of Immune System Process
Regulation Of Type I Interferon Production
Immune Response-regulating Signaling Pathway
Type I Interferon Production
Immune Response
Regulation Of Immune System Process
Defense Response
Response To Other Organism
Response To Biotic Stimulus
Regulation Of Toll-like Receptor Signaling Pathway
Regulation Of Interferon-beta Production
Immune System Process
Positive Regulation Of Cytokine Production
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Protein Binding
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Type I Interferon Production
Response To Organic Substance
Positive Regulation Of Cellular Metabolic Process
Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway
Positive Regulation Of Interleukin-15 Production
Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production
TIRAP-dependent Toll-like Receptor 4 Signaling Pathway
Regulation Of Cytokine-mediated Signaling Pathway
Regulation Of Cytokine Production
Cellular Response To Cytokine Stimulus
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Binding
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Toll-like Receptor 2 Signaling Pathway
MDA-5 Signaling Pathway
Positive Regulation Of Cellular Biosynthetic Process
Cytokine Production
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Type I Interferon Production
Activation Of Innate Immune Response
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Innate Immune Response
Regulation Of Type I Interferon Production
Toll-like Receptor Signaling Pathway
Positive Regulation Of Cytokine Production
TRIF-dependent Toll-like Receptor Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Regulation Of Innate Immune Response
Positive Regulation Of Intracellular Signal Transduction
Innate Immune Response
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Signal Transduction
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
N-terminal Peptidyl-lysine Acetylation
Immune Response
Response To Biotic Stimulus
Regulation Of Cytokine Production
Viral Process
Regulation Of Signaling
Regulation Of Intracellular Signal Transduction
Intracellular Signal Transduction
Positive Regulation Of Interferon-beta Production
Cellular Response To Lipopolysaccharide
Response To Stress
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Cellular Response To Molecule Of Bacterial Origin
Immune Response-regulating Signaling Pathway
Positive Regulation Of Signal Transduction
Response To Bacterium
Defense Response
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Cellular Response To Stimulus
Regulation Of Interferon-beta Production
Lipopolysaccharide-mediated Signaling Pathway
Signal Transduction
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Cytokine Biosynthetic Process
Positive Regulation Of Chemokine Production
Tagcloud
?
abolished
activator
amlexanox
aortic
augment
augmentation
augmented
end
endothelial
epsilon
gamma
ifn
ikappab
ikk
inducible
interferon
jak
janus
murine
nitric
oxide
poly
production
stat
synthase
tank
tbk
transducer
Tagcloud (Difference)
?
abolished
activator
amlexanox
aortic
augment
augmentation
augmented
end
endothelial
epsilon
gamma
ifn
ikappab
ikk
inducible
interferon
jak
janus
murine
nitric
oxide
poly
production
stat
synthase
tank
tbk
transducer
Tagcloud (Intersection)
?