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CCDC47 and TOM1L1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CCDC47
TOM1L1
Gene Name
coiled-coil domain containing 47
target of myb1 (chicken)-like 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum
Membrane
Integral Component Of Membrane
Cytoplasm
Lysosome
Endosome
Golgi Stack
Cytosol
Endosome Membrane
Extracellular Vesicular Exosome
Molecular Function
Calcium Ion Binding
Protein Binding
Poly(A) RNA Binding
Protein Binding
SH3 Domain Binding
Protein Kinase Binding
Clathrin Binding
Protein Kinase Activator Activity
Ubiquitin Binding
Biological Process
Osteoblast Differentiation
ER Overload Response
Post-embryonic Development
Calcium Ion Homeostasis
Intracellular Protein Transport
Signal Transduction
Positive Regulation Of Protein Autophosphorylation
Activation Of Protein Kinase Activity
Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway
Negative Regulation Of Mitotic Nuclear Division
Regulation Of DNA Biosynthetic Process
Pathways
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
7 interactors:
IRAK1
IRF7
RPL7A
SARM1
TIRAP
TMEM173
TOM1L1
27 interactors:
AMFR
CCDC47
CELF1
COPS7A
CWF19L1
FAM208A
FYN
GLUD2
GRB2
GSN
HGS
HNRNPH1
MAP3K3
NDC80
NOMO1
PDPN
PELP1
PHYH
PIK3R1
PWP2
RAB18
TOLLIP
TSG101
TUBA1B
UBXN4
VAV2
VCP
Entrez ID
57003
10040
HPRD ID
17041
05266
Ensembl ID
ENSG00000108588
ENSG00000141198
Uniprot IDs
Q96A33
B7Z9E2
I3L4I4
O75674
PDB IDs
3RRU
Enriched GO Terms of Interacting Partners
?
Activation Of Innate Immune Response
Positive Regulation Of Innate Immune Response
Regulation Of Innate Immune Response
Toll-like Receptor 4 Signaling Pathway
Toll-like Receptor Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Interferon-beta Production
Positive Regulation Of Immune Response
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Innate Immune Response
Regulation Of Immune Response
Positive Regulation Of Immune System Process
Regulation Of Type I Interferon Production
Immune Response-regulating Signaling Pathway
Type I Interferon Production
Immune Response
Regulation Of Immune System Process
Defense Response
Response To Other Organism
Response To Biotic Stimulus
Regulation Of Toll-like Receptor Signaling Pathway
Regulation Of Interferon-beta Production
Immune System Process
Positive Regulation Of Cytokine Production
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Toll-like Receptor 2 Signaling Pathway
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Protein Binding
MyD88-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Type I Interferon Production
Response To Organic Substance
Positive Regulation Of Cellular Metabolic Process
Regulation Of MyD88-independent Toll-like Receptor Signaling Pathway
Positive Regulation Of Interleukin-15 Production
Positive Regulation Of Chemokine (C-X-C Motif) Ligand 1 Production
TIRAP-dependent Toll-like Receptor 4 Signaling Pathway
Regulation Of Cytokine-mediated Signaling Pathway
Regulation Of Cytokine Production
Cellular Response To Cytokine Stimulus
Positive Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Binding
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Toll-like Receptor 2 Signaling Pathway
MDA-5 Signaling Pathway
Positive Regulation Of Cellular Biosynthetic Process
Cytokine Production
Phosphatidylinositol-mediated Signaling
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Response To Endoplasmic Reticulum Stress
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Platelet Activation
Positive Regulation Of Exosomal Secretion
Regulation Of Exosomal Secretion
Neurotrophin TRK Receptor Signaling Pathway
T Cell Costimulation
Neurotrophin Signaling Pathway
Fc-epsilon Receptor Signaling Pathway
Response To Organic Substance
Phagocytosis
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of RNA Splicing
Fc Receptor Signaling Pathway
ER-nucleus Signaling Pathway
Immune Response-activating Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Activation
Wound Healing
Response To Unfolded Protein
Response To Stress
Intracellular Signal Transduction
Cellular Response To Organic Substance
Cellular Component Assembly
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Vesicle-mediated Transport
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cell Activation
Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Protein Complex Assembly
Response To Wounding
ER-associated Ubiquitin-dependent Protein Catabolic Process
Blood Coagulation
Hemostasis
Cellular Response To Stimulus
Cellular Response To Fibroblast Growth Factor Stimulus
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Response To Fibroblast Growth Factor
Positive Regulation Of Lys63-specific Deubiquitinase Activity
Positive Regulation Of Protein K63-linked Deubiquitination
NFAT Protein Import Into Nucleus
Regulation Of Phosphatidylinositol 3-kinase Activity
Negative Regulation Of ERBB Signaling Pathway
Signal Transduction
Immune Response-regulating Signaling Pathway
Positive Regulation Of T Cell Activation
Tagcloud
?
adaptor
behave
bridged
clathrin
cytosolic
defective
egf
egfr
elusive
endocytic
endocytosis
endosome
engage
exogenous
grb2
incapable
knocked
machinery
onto
participate
redistributes
rescue
rnai
shc
stimulates
tail
transient
triggers
tyr
Tagcloud (Difference)
?
adaptor
behave
bridged
clathrin
cytosolic
defective
egf
egfr
elusive
endocytic
endocytosis
endosome
engage
exogenous
grb2
incapable
knocked
machinery
onto
participate
redistributes
rescue
rnai
shc
stimulates
tail
transient
triggers
tyr
Tagcloud (Intersection)
?