TOM1L1 and GLUD2

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOM1L1	GLUD2
Gene Name		target of myb1 (chicken)-like 1	glutamate dehydrogenase 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Lysosome Endosome Golgi Stack Cytosol Endosome Membrane Extracellular Vesicular Exosome	Cytoplasm Mitochondrion
	Molecular Function	Protein Binding SH3 Domain Binding Protein Kinase Binding Clathrin Binding Protein Kinase Activator Activity Ubiquitin Binding	Glutamate Dehydrogenase (NAD+) Activity Glutamate Dehydrogenase [NAD(P)+] Activity GTP Binding ADP Binding Leucine Binding
	Biological Process	Intracellular Protein Transport Signal Transduction Positive Regulation Of Protein Autophosphorylation Activation Of Protein Kinase Activity Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Negative Regulation Of Mitotic Nuclear Division Regulation Of DNA Biosynthetic Process	Glutamate Metabolic Process Glutamate Biosynthetic Process Glutamate Catabolic Process Oxidation-reduction Process
Pathways
Drugs			L-Glutamic Acid NADH Nicotinamide-Adenine-Dinucleotide
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		27 interactors: AMFR CCDC47 CELF1 COPS7A CWF19L1 FAM208A FYN GLUD2 GRB2 GSN HGS HNRNPH1 MAP3K3 NDC80 NOMO1 PDPN PELP1 PHYH PIK3R1 PWP2 RAB18 TOLLIP TSG101 TUBA1B UBXN4 VAV2 VCP	1 interactors: TOM1L1
Entrez ID		10040	2747
HPRD ID		05266	02143
Ensembl ID		ENSG00000141198	ENSG00000182890
Uniprot IDs		B7Z9E2 I3L4I4 O75674	P49448
PDB IDs		3RRU
Enriched GO Terms of Interacting Partners?		Phosphatidylinositol-mediated Signaling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Response To Endoplasmic Reticulum Stress Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Platelet Activation Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Neurotrophin TRK Receptor Signaling Pathway T Cell Costimulation Neurotrophin Signaling Pathway Fc-epsilon Receptor Signaling Pathway Response To Organic Substance Phagocytosis Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing Fc Receptor Signaling Pathway ER-nucleus Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Activation Wound Healing Response To Unfolded Protein Response To Stress Intracellular Signal Transduction Cellular Response To Organic Substance Cellular Component Assembly Immune Response-regulating Cell Surface Receptor Signaling Pathway Vesicle-mediated Transport Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Activation Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Protein Complex Assembly Response To Wounding ER-associated Ubiquitin-dependent Protein Catabolic Process Blood Coagulation Hemostasis Cellular Response To Stimulus Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Response To Fibroblast Growth Factor Positive Regulation Of Lys63-specific Deubiquitinase Activity Positive Regulation Of Protein K63-linked Deubiquitination NFAT Protein Import Into Nucleus Regulation Of Phosphatidylinositol 3-kinase Activity Negative Regulation Of ERBB Signaling Pathway Signal Transduction Immune Response-regulating Signaling Pathway Positive Regulation Of T Cell Activation	Positive Regulation Of Protein Autophosphorylation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Protein Autophosphorylation Negative Regulation Of Mitotic Nuclear Division Negative Regulation Of Cell Division
Tagcloud ?		adaptor behave bridged clathrin cytosolic defective egf egfr elusive endocytic endocytosis endosome engage exogenous grb2 incapable knocked machinery onto participate redistributes rescue rnai shc stimulates tail transient triggers tyr	alcoholics automatic brains caudate cortices dorsal epsilon excitatory executive gaba gamma1 glud1 glun2a glutamate ionotropic mortem movements mrnas outputs prominently putamen qpcr rho2 seeking striatal striatum thinking underlie voluntarily
Tagcloud (Difference) ?		adaptor behave bridged clathrin cytosolic defective egf egfr elusive endocytic endocytosis endosome engage exogenous grb2 incapable knocked machinery onto participate redistributes rescue rnai shc stimulates tail transient triggers tyr	alcoholics automatic brains caudate cortices dorsal epsilon excitatory executive gaba gamma1 glud1 glun2a glutamate ionotropic mortem movements mrnas outputs prominently putamen qpcr rho2 seeking striatal striatum thinking underlie voluntarily
Tagcloud (Intersection) ?