BAAT and CTNNA1

Number of citations of the paper that reports this interaction (PubMedID 24412244)
0

Data Source:
BioGRID (two hybrid)

		BAAT	CTNNA1
Description		bile acid-CoA:amino acid N-acyltransferase	catenin alpha 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisome Peroxisomal Matrix Cytosol	Acrosomal Vesicle Nucleus Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Zonula Adherens Focal Adhesion Intercalated Disc Actin Cytoskeleton Membrane Catenin Complex Flotillin Complex Lamellipodium Cell Junction Anchoring Junction Plasma Membrane Protein Complex
	Molecular Function	Protein Binding N-acyltransferase Activity Transferase Activity Acyltransferase Activity Hydrolase Activity Thiolester Hydrolase Activity Choloyl-CoA Hydrolase Activity Fatty Acyl-CoA Hydrolase Activity Glycine N-choloyltransferase Activity Carboxylic Ester Hydrolase Activity Medium-chain Fatty Acyl-CoA Hydrolase Activity Long-chain Fatty Acyl-CoA Hydrolase Activity Very Long-chain Fatty Acyl-CoA Hydrolase Activity	RNA Binding Structural Molecule Activity Protein Binding Beta-catenin Binding Cytoskeletal Protein Binding Vinculin Binding Identical Protein Binding Protein-containing Complex Binding Gamma-catenin Binding Cadherin Binding Actin Filament Binding
	Biological Process	Liver Development Bile Acid Conjugation Glycine Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Bile Acid Biosynthetic Process Bile Acid Metabolic Process Taurine Metabolic Process Animal Organ Regeneration Monocarboxylic Acid Metabolic Process	Ovarian Follicle Development Apoptotic Process Cell Adhesion Establishment Or Maintenance Of Cell Polarity Smoothened Signaling Pathway Integrin-mediated Signaling Pathway Neuroblast Proliferation Negative Regulation Of Neuroblast Proliferation Intracellular Protein Localization Male Gonad Development Gap Junction Assembly Cell Migration Axon Regeneration Regulation Of Cell Population Proliferation Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Apoptotic Process Apical Junction Assembly Response To Estrogen Positive Regulation Of Smoothened Signaling Pathway Cell Motility Cellular Response To Indole-3-methanol Epithelial Cell-cell Adhesion Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Cell Motility Negative Regulation Of Integrin-mediated Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways		Recycling of bile acids and salts Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Peroxisomal protein import Peroxisomal protein import	Adherens junctions interactions VEGFR2 mediated vascular permeability Myogenesis Myogenesis RHO GTPases activate IQGAPs Regulation of CDH11 function Regulation of CDH19 Expression and Function Regulation of CDH1 Function Degradation of CDH1 CDH11 homotypic and heterotypic interactions
Drugs		Glycine
Diseases		Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
GWAS			Femur bone mineral density x serum urate levels interaction ( 34046847) General risk tolerance (MTAG) ( 30643258) Malaria ( 31844061) Schizophrenia ( 25056061)
Interacting Genes		24 interacting genes: APC AURKA BCL10 BUB1 CDKN2A CTNNA1 DLC1 ERBB2 GOLGA8DP GOLGA8EP GOLGA8F MCC MLH1 MLH3 MUTYH ODC1 PDGFRL PEX5 PTPRJ RAD54B RB1 SLC7A11 SMAD4 SRC	55 interacting genes: ACTN1 AFDN AJUBA AKT1 ALDOB APP ARMC8 BAAT CA9 CCDC180 CDC42 CDH1 CDH15 CDH2 CDH3 CDH5 CSNK2A1 CTBP1 CTNNB1 CTSV DLG1 DYRK1A EIF4ENIF1 F2RL1 FBP1 FBP2 FRAT2 HRAS HSD17B3 HSPA13 JUP LRATD2 MAP2K1 MTNR1A MTNR1B NANS PKD1 PSEN1 RBM26 RNF10 SASH1 SFRP2 SFRP4 SMAD1 SPTAN1 SPTBN1 STX17 TDRD7 TJP1 TJP2 UBE2I VCL ZGPAT ZNF189 ZNF510
Entrez ID		570	1495
HPRD ID		08376	00285
Ensembl ID		ENSG00000136881	ENSG00000044115
Uniprot IDs		Q14032	A0A384MDY0 B4DKT9 B4DU00 G3XAM7 P35221
PDB IDs			1H6G 4EHP 4IGG 6UPV 6V2O 6V2P 7UTJ 9BL2 9BL3 9BL4
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Population Proliferation Regulation Of Programmed Cell Death Ruffle Membrane Regulation Of Protein Kinase Activity Regulation Of Protein Serine/threonine Kinase Activity Gamma-catenin Binding Regulation Of Apoptotic Process Regulation Of Kinase Activity Regulation Of Phosphorylation Chiasma Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Regulation Of Cell Population Proliferation Reciprocal Meiotic Recombination Mismatch Repair Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Protein Phosphorylation Response To Stress Regulation Of Protein Modification Process Regulation Of Mitotic Nuclear Division Regulation Of Protein Metabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of Programmed Cell Death Homologous Recombination Mismatch Repair Complex Cellular Response To Stress Negative Regulation Of Immature T Cell Proliferation Regulation Of Cell-matrix Adhesion Regulation Of Cellular Component Organization MutSalpha Complex Binding Regulation Of Nuclear Division Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Phosphate Metabolic Process Positive Regulation Of Apoptotic Process Intracellular Signal Transduction Apoptotic Signaling Pathway Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Cell Growth Negative Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Programmed Cell Death Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell-substrate Adhesion Regulation Of Catalytic Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Mismatched DNA Binding	Cell-cell Junction Organization Cell Junction Organization Adherens Junction Cadherin Binding Adherens Junction Organization Cell Junction Assembly Cell-cell Junction Assembly Cell Junction Cell-cell Adhesion Catenin Complex Cell-cell Junction Cell-cell Adhesion Mediated By Cadherin Alpha-catenin Binding Anchoring Junction Cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Fascia Adherens Anatomical Structure Morphogenesis Regulation Of Cell Motility Regulation Of Protein Localization Glutamatergic Synapse Regulation Of Locomotion Beta-catenin Binding Regulation Of Cell Migration Positive Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Component Organization Plasma Membrane Cellular Response To Indole-3-methanol Regulation Of Supramolecular Fiber Organization Cell Development Regulation Of Cell Population Proliferation Response To Indole-3-methanol Cytoplasm Cortical Actin Cytoskeleton Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Wnt Signaling Pathway Positive Regulation Of Gene Expression Regulation Of DNA-templated Transcription Developmental Process Regulation Of RNA Biosynthetic Process Regulation Of Cell Adhesion Negative Regulation Of Signal Transduction Regulation Of Canonical Wnt Signaling Pathway Regulation Of Multicellular Organismal Development Positive Regulation Of Angiogenesis Positive Regulation Of Macromolecule Biosynthetic Process Protein Kinase Binding Fructose 1,6-bisphosphate Metabolic Process Regulation Of RNA Metabolic Process
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