BAAT and SLC7A11

Number of citations of the paper that reports this interaction (PubMedID 12763038)
0

Data Source:
HPRD (in vitro)

		BAAT	SLC7A11
Description		bile acid-CoA:amino acid N-acyltransferase	solute carrier family 7 member 11
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Peroxisome Peroxisomal Matrix Cytosol	Plasma Membrane Cell Surface Membrane Brush Border Membrane Microvillus Membrane Cell Projection Apical Part Of Cell Astrocyte Projection
	Molecular Function	Protein Binding N-acyltransferase Activity Transferase Activity Acyltransferase Activity Hydrolase Activity Thiolester Hydrolase Activity Choloyl-CoA Hydrolase Activity Fatty Acyl-CoA Hydrolase Activity Glycine N-choloyltransferase Activity Carboxylic Ester Hydrolase Activity Medium-chain Fatty Acyl-CoA Hydrolase Activity Long-chain Fatty Acyl-CoA Hydrolase Activity Very Long-chain Fatty Acyl-CoA Hydrolase Activity	Protein Binding L-amino Acid Transmembrane Transporter Activity Cystine:glutamate Antiporter Activity Transmembrane Transporter Activity L-kynurenine Transmembrane Transporter Activity
	Biological Process	Liver Development Bile Acid Conjugation Glycine Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process Bile Acid Biosynthetic Process Bile Acid Metabolic Process Taurine Metabolic Process Animal Organ Regeneration Monocarboxylic Acid Metabolic Process	Amino Acid Transmembrane Transport Glutathione Metabolic Process Amino Acid Transport Brain Development Visual Learning Response To Toxic Substance L-cystine Transport L-glutamate Transmembrane Transport Ventricular System Development Striatum Development Adult Behavior Regulation Of Neutrophil Apoptotic Process Cellular Response To Stress Cellular Response To Oxidative Stress Glutathione Transmembrane Transport Regulation Of Cell Population Proliferation Regulation Of Programmed Cell Death Regulation Of Melanin Biosynthetic Process Lung Alveolus Development Modulation Of Chemical Synaptic Transmission Regulation Of Synapse Organization Regulation Of Protein Transport Response To Redox State Transmembrane Transport Limb Development Platelet Aggregation Intracellular Glutamate Homeostasis L-glutamate Import Across Plasma Membrane Negative Regulation Of Ferroptosis Dipeptide Import Across Plasma Membrane L-kynurenine Transmembrane Transport Regulation Of Cellular Response To Oxidative Stress Regulation Of Cysteine Metabolic Process Regulation Of Glutathione Biosynthetic Process Regulation Of AMPA Glutamate Receptor Clustering Regulation Of Glutamate Metabolic Process
Pathways		Recycling of bile acids and salts Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Peroxisomal protein import Peroxisomal protein import	Basigin interactions Amino acid transport across the plasma membrane NFE2L2 regulating anti-oxidant/detoxification enzymes
Drugs		Glycine	Cystine Glutamic acid Riluzole Sulfasalazine Acetylcysteine Thimerosal
Diseases		Peroxisomal beta-oxidation enzyme deficiency, including: Acyl-CoA oxidase (ACOX) deficiency; D-bifunctional protein (DBP) deficiency; Perrault syndrome; Sterol carrier protein X (SCPx) deficiency; 2-Methylacyl-CoA racemase (AMCR) deficiency; Hypercholanemia
GWAS			Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Mood instability ( 31168069) Neurociticism ( 29500382) Sleep duration (> 10 hours) ( 33075057)
Interacting Genes		24 interacting genes: APC AURKA BCL10 BUB1 CDKN2A CTNNA1 DLC1 ERBB2 GOLGA8DP GOLGA8EP GOLGA8F MCC MLH1 MLH3 MUTYH ODC1 PDGFRL PEX5 PTPRJ RAD54B RB1 SLC7A11 SMAD4 SRC	7 interacting genes: BAAT KRTAP1-1 KRTAP1-3 PCBP2 SLC3A2 TERT ZRANB1
Entrez ID		570	23657
HPRD ID		08376	09720
Ensembl ID		ENSG00000136881	ENSG00000151012
Uniprot IDs		Q14032	Q9UPY5
PDB IDs			7CCS 7EPZ 7P9U 7P9V
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cell Population Proliferation Regulation Of Programmed Cell Death Ruffle Membrane Regulation Of Protein Kinase Activity Regulation Of Protein Serine/threonine Kinase Activity Gamma-catenin Binding Regulation Of Apoptotic Process Regulation Of Kinase Activity Regulation Of Phosphorylation Chiasma Negative Regulation Of Protein Kinase Activity Negative Regulation Of Kinase Activity Regulation Of Cell Population Proliferation Reciprocal Meiotic Recombination Mismatch Repair Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Negative Regulation Of Protein Serine/threonine Kinase Activity Negative Regulation Of Protein Phosphorylation Response To Stress Regulation Of Protein Modification Process Regulation Of Mitotic Nuclear Division Regulation Of Protein Metabolic Process Negative Regulation Of Phosphorylation Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Immature T Cell Proliferation In Thymus Negative Regulation Of Programmed Cell Death Homologous Recombination Mismatch Repair Complex Cellular Response To Stress Negative Regulation Of Immature T Cell Proliferation Regulation Of Cell-matrix Adhesion Regulation Of Cellular Component Organization MutSalpha Complex Binding Regulation Of Nuclear Division Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Negative Regulation Of Catalytic Activity Negative Regulation Of Phosphate Metabolic Process Positive Regulation Of Apoptotic Process Intracellular Signal Transduction Apoptotic Signaling Pathway Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Cell Growth Negative Regulation Of T Cell Differentiation In Thymus Positive Regulation Of Programmed Cell Death Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Cell-substrate Adhesion Regulation Of Catalytic Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Mismatched DNA Binding	Glycine N-choloyltransferase Activity Bile Acid Conjugation Apical Pole Of Neuron TERT-RMRP Complex Template-free RNA Nucleotidyltransferase Positive Regulation Of Transdifferentiation RNA-directed RNA Polymerase Complex SiRNA Transcription Medium-chain Fatty Acyl-CoA Hydrolase Activity Choloyl-CoA Hydrolase Activity Very Long-chain Fatty Acyl-CoA Hydrolase Activity Exogenous Protein Binding Amino Acid Transport Complex Positive Regulation Of Hair Cycle Telomerase Catalytic Core Complex Keratin Filament Methionine Transport L-leucine Import Across Plasma Membrane Aromatic Amino Acid Transmembrane Transporter Activity Tyrosine Transport RNA-directed RNA Polymerase Activity RNA-templated Transcription RNA-directed DNA Polymerase Activity L-histidine Transport Phenylalanine Transport Valine Transport L-alanine Import Across Plasma Membrane Positive Regulation Of Wnt Signaling Pathway Protein K29-linked Deubiquitination Isoleucine Transport L-leucine Transmembrane Transporter Activity L-alanine Transmembrane Transport Tryptophan Transport Protein K33-linked Deubiquitination Intermediate Filament Promoter-enhancer Loop Anchoring Activity L-alanine Transmembrane Transporter Activity Positive Regulation Of Protein Localization To Nucleolus Protein Deubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Viral RNA Genome Replication Telomerase Activity Establishment Of Protein Localization To Telomere L-alanine Transport SiRNA Processing N-acyltransferase Activity Thiolester Hydrolase Activity L-leucine Transport Proline Transport Nuclear Telomere Cap Complex Taurine Metabolic Process
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