MFF and APOD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MFF	APOD
Description		mitochondrial fission factor	apolipoprotein D
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisome Synaptic Vesicle Membrane Cytoplasmic Vesicle Mitochondrial Membrane Protein-containing Complex Synapse	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Cytosolic Ribosome Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity	Lipid Transporter Activity Protein Binding Lipid Binding Cholesterol Binding
	Biological Process	Mitochondrial Fission Protein Targeting To Mitochondrion Mitochondrion Organization Peroxisome Fission Positive Regulation Of Mitochondrial Fission	Response To Reactive Oxygen Species Angiogenesis Glucose Metabolic Process Lipid Metabolic Process Lipid Transport Response To Stress Brain Development Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Peripheral Nervous System Axon Regeneration Tissue Regeneration Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Smooth Muscle Cell Proliferation Response To Axon Injury Negative Regulation Of Focal Adhesion Assembly Negative Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of T Cell Migration
Pathways			Transport of fatty acids NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs			Vitamin A Copper
Diseases
GWAS		Intraocular pressure ( 29617998) Refractive astigmatism ( 30306274)	HDL cholesterol levels ( 32203549)
Interacting Genes		107 interacting genes: ADIPOQ AGPAT4 AIG1 ANKRD46 APOD APOL2 AQP3 AQP6 ATP6V0B BET1 C14orf180 C1QL4 C3orf52 CD79A CDIPT CEND1 CLDN19 CMTM5 CNIH1 COL4A5 CTXN3 CXCL16 CYB5B CYBC1 DNM1L ERGIC3 FAM209A FAM210B FAM3C FATE1 FCER1G FDCSP FXYD6 GJB1 GKN1 GOSR2 GPR152 IGFBP5 JAGN1 LAT LHFPL5 LPAR3 MEOX2 MIP MMGT1 MOSPD3 MPZL1 MTNR1B NIPAL3 NRM NTS OPN1SW OPRM1 PLK3 PLLP PLN PLP1 RAET1L RETREG3 RHBDL1 SACM1L SEC11C SEC22A SEC22B SEC23A SERINC2 SHISAL1 SLC18A3 SLC35B1 SLC41A2 SLC7A1 SLC7A14 SLC7A8 SMIM1 STRIT1 STX7 STX8 TEX264 TFRC TM6SF1 TMEM128 TMEM140 TMEM14C TMEM201 TMEM218 TMEM229B TMEM237 TMEM254 TMEM42 TMEM60 TMEM86B TMEM88 TMEM97 TMX2 TRAF3 TRAF3IP3 TRAM1L1 TRARG1 TSPAN2 TSPAN33 TSPO2 UBC UNC50 UNC93B1 UPK1B VAMP4 ZFPL1	51 interacting genes: AIG1 APH1A APOA2 AQP9 ATP6V0B ATP6V0E1 BCL2L13 BIK CD53 CD79A CLDN7 CLEC10A CPLX4 CREB3 CREB3L1 ERGIC3 EVI2B FAM209A FFAR2 FKBP7 FPR2 GDAP1 GJA8 GORAB GPR151 GPR42 GPX8 KCNJ6 KIR2DL3 LEPR LMNA MFF MGST3 MTERF2 MTIF3 NCAPH2 PDZK1IP1 POLR2M RHBDL1 SHBG SIGLECL1 SLC10A6 SLC35H1 TEX29 TMEM237 TMEM31 TMEM45B TMEM52B TMEM79 VAPA VSIR
Entrez ID		56947	347
HPRD ID		16653	00134
Ensembl ID		ENSG00000168958	ENSG00000189058
Uniprot IDs		A0A0A0MS29 A0A9H3ZVE5 A0A9L9PY92 H7C433 Q9GZY8	P05090
PDB IDs			2HZQ 2HZR
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding SNAP Receptor Activity SNARE Complex Golgi Membrane Mitochondrial Outer Membrane Endomembrane System Membrane Fusion Water Channel Activity Vesicle-mediated Transport Magnesium Ion Transmembrane Transporter Activity Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Magnesium Ion Transmembrane Transport Plasma Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Magnesium Ion Transport Organelle Fusion Transmembrane Transport Protein Localization To Plasma Membrane Membrane Organization Nuclear Inner Membrane Vesicle Fusion Regulation Of Protein Transport Cellular Localization Regulation Of Cellular Localization Water Transport Golgi Apparatus Organelle Membrane Fusion ER To Golgi Transport Vesicle Membrane Protein Localization To Cell Periphery Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Cone Photoreceptor Outer Segment Chloride Channel Inhibitor Activity Inorganic Cation Transmembrane Transporter Activity Vesicle Organization Myelin Sheath Amino Acid Transmembrane Transporter Activity Negative Regulation Of Protein Transport Renal Water Transport Myeloid Cell Differentiation Neutrophil Differentiation Cobalt Ion Transport	Membrane Protein Binding
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