APOD and MTERF2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		APOD	MTERF2
Description		apolipoprotein D	mitochondrial transcription termination factor 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Cytosolic Ribosome Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Exosome	Mitochondrion Mitochondrial Matrix Mitochondrial Nucleoid
	Molecular Function	Lipid Transporter Activity Protein Binding Lipid Binding Cholesterol Binding	Nucleic Acid Binding DNA Binding Protein Binding
	Biological Process	Response To Reactive Oxygen Species Angiogenesis Glucose Metabolic Process Lipid Metabolic Process Lipid Transport Response To Stress Brain Development Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Peripheral Nervous System Axon Regeneration Tissue Regeneration Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Smooth Muscle Cell Proliferation Response To Axon Injury Negative Regulation Of Focal Adhesion Assembly Negative Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of T Cell Migration	Termination Of Mitochondrial Transcription
Pathways		Transport of fatty acids NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux
Drugs		Vitamin A Copper
Diseases
GWAS		HDL cholesterol levels ( 32203549)
Interacting Genes		51 interacting genes: AIG1 APH1A APOA2 AQP9 ATP6V0B ATP6V0E1 BCL2L13 BIK CD53 CD79A CLDN7 CLEC10A CPLX4 CREB3 CREB3L1 ERGIC3 EVI2B FAM209A FFAR2 FKBP7 FPR2 GDAP1 GJA8 GORAB GPR151 GPR42 GPX8 KCNJ6 KIR2DL3 LEPR LMNA MFF MGST3 MTERF2 MTIF3 NCAPH2 PDZK1IP1 POLR2M RHBDL1 SHBG SIGLECL1 SLC10A6 SLC35H1 TEX29 TMEM237 TMEM31 TMEM45B TMEM52B TMEM79 VAPA VSIR	3 interacting genes: APOD SACM1L STX6
Entrez ID		347	80298
HPRD ID		00134	17431
Ensembl ID		ENSG00000189058	ENSG00000120832
Uniprot IDs		P05090	Q49AM1
PDB IDs		2HZQ 2HZR
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding	Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Exocytic Insertion Of Neurotransmitter Receptor To Postsynaptic Membrane Synaptic Vesicle To Endosome Fusion Phosphatidylinositol-4-phosphate Phosphatase Activity Regulation Of Smooth Muscle Cell-matrix Adhesion Phosphatidylinositol Phosphate 4-phosphatase Activity Negative Regulation Of Lipoprotein Metabolic Process Peripheral Nervous System Axon Regeneration Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of T Cell Migration Endoplasmic Reticulum-plasma Membrane Contact Site Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Lipoprotein Metabolic Process Phosphatidylinositol-3-phosphate Phosphatase Activity Negative Regulation Of Lymphocyte Migration Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Focal Adhesion Assembly Perinuclear Region Of Cytoplasm Negative Regulation Of Chemokine Production Lipid Transporter Activity Neuron Projection Regeneration Axon Regeneration Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Golgi Membrane Phosphatidylinositol Dephosphorylation AMPA Glutamate Receptor Complex Negative Regulation Of Intracellular Protein Transport Negative Regulation Of Mononuclear Cell Migration SNAP Receptor Activity Phospholipid Dephosphorylation Negative Regulation Of Cell-matrix Adhesion Negative Regulation Of Protein Localization To Nucleus Response To Axon Injury Cholesterol Binding Regulation Of T Cell Migration Negative Regulation Of Cytokine Production Involved In Inflammatory Response Tissue Regeneration Regulation Of Protein Localization SNARE Complex Syntaxin Binding Organelle Membrane Axon Development Negative Regulation Of Leukocyte Migration Negative Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Intracellular Transport Lipid Metabolic Process Regulation Of Protein Import Into Nucleus Negative Regulation Of Cell-substrate Adhesion
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