APOD and BCL2L13

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		APOD	BCL2L13
Name		apolipoprotein D	BCL2 like 13
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Cytosolic Ribosome Dendrite Neuronal Cell Body Perinuclear Region Of Cytoplasm Extracellular Exosome	Nucleus Mitochondrion Membrane Mitochondrial Membrane
	Molecular Function	Lipid Transporter Activity Protein Binding Lipid Binding Cholesterol Binding	Protein Binding Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
	Biological Process	Response To Reactive Oxygen Species Angiogenesis Glucose Metabolic Process Lipid Metabolic Process Lipid Transport Response To Stress Brain Development Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Peripheral Nervous System Axon Regeneration Tissue Regeneration Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Smooth Muscle Cell Proliferation Response To Axon Injury Negative Regulation Of Focal Adhesion Assembly Negative Regulation Of Lipoprotein Lipid Oxidation Negative Regulation Of Monocyte Chemotactic Protein-1 Production Negative Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of Smooth Muscle Cell-matrix Adhesion Negative Regulation Of T Cell Migration	Mitophagy Oxidative Phosphorylation Apoptotic Process Mitochondrion Organization Regulation Of Apoptotic Process Fat Cell Differentiation Canonical Glycolysis
Pathways		Transport of fatty acids NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux	None
Drugs		Vitamin A Copper	None
GWAS		HDL cholesterol levels ( 32203549 )	Baseline cortisol levels in response to low dose short synacthen test in corticosteroid treated asthma ( 29551627 ) Eosinophil count ( 32888494 ) Granulocyte count ( 27863252 ) Hemoglobin levels ( 32327693 ) Interleukin-10 levels ( 22205395 ) Lymphocyte percentage of white cells ( 32888494 ) Monocyte count ( 32888494 ) Myeloid white cell count ( 27863252 ) Neutrophil count ( 27863252 32888494 ) Neutrophil percentage of white cells ( 32888494 ) Sum neutrophil eosinophil counts ( 27863252 ) White blood cell count ( 32888494 )
Novel Interactors		None recorded	1 novel interactors: IL17RA
Interacting Genes		51 interacting genes: AIG1 APH1A APOA2 AQP9 ATP6V0B ATP6V0E1 BCL2L13 BIK CD53 CD79A CLDN7 CLEC10A CPLX4 CREB3 CREB3L1 ERGIC3 EVI2B FAM209A FFAR2 FKBP7 FPR2 GDAP1 GJA8 GORAB GPR151 GPR42 GPX8 KCNJ6 KIR2DL3 LEPR LMNA MFF MGST3 MTERF2 MTIF3 NCAPH2 PDZK1IP1 POLR2M RHBDL1 SHBG SIGLECL1 SLC10A6 SLC35H1 TEX29 TMEM237 TMEM31 TMEM45B TMEM52B TMEM79 VAPA VSIR	84 interacting genes: ACP5 ADIPOQ AGTRAP AIG1 APOD APP AQP1 ARL6IP1 ARLN BAZ2B BCL9 BET1 CAMLG CD53 CDC42 CDK5R1 CERS6 CLDN19 CRB3 DEFB127 ERG28 ERMP1 ETNK2 FAM210B FUS FXYD3 FZD7 GABARAPL2 GALNT2 GAST GTF2F1 HMOX2 HNRNPK IDI1 JAGN1 JPH4 LAT LAYN LPAR3 MAL MGMT MTNR1B NDRG4 NETO2 NINJ2 NR2C2AP NRBP1 PCBP1 PLLP PLN PLP1 PLPP4 PPT2 RPN2 SH3RF3 SLC30A8 SLC35A1 SLC35G5 SMARCD3 SMIM1 SPOCK1 SQLE SRSF3 STX12 STX8 TM6SF2 TMEM128 TMEM14C TMEM242 TMEM254 TMEM51 TMEM72 TMEM86A TMEM86B TMEM97 TMUB2 TNF TNMD TRARG1 TUBB UBC UPK1B VAMP3 VAMP4
Entrez ID		347	23786
HPRD ID		00134	09822
Ensembl ID		ENSG00000189058	ENSG00000099968
Uniprot IDs		P05090	A0A087WTL4 A0A087WW80 A0A087WX97 A0A0A0MR90 A8K5Y4 B2RB43 B7Z238 B7Z737 E9PDD6 F2Z2C3 F6VJB4 Q9BXK5
PDB IDs		2HZQ 2HZR	Not available
GO Terms Enriched among Interactors		Membrane Protein Binding	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Localization Within Membrane SNARE Complex Cellular Localization Response To Type II Interferon Structural Constituent Of Myelin Sheath Protein Binding Regulation Of Transport Alkenylglycerophosphocholine Hydrolase Activity Cellular Response To Type II Interferon SNAP Receptor Activity Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Organelle Fusion Regulation Of Cellular Localization Phagocytic Vesicle Membrane Raft Regulation Of Chemokine Production Protein Localization To Membrane Protein Localization To Cell Periphery Vesicle Fusion Vesicle Organization Organelle Membrane Fusion Negative Regulation Of Blood Circulation Vesicle Docking Regulation Of Establishment Of Protein Localization Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Protein Transport Response To Cytokine Protein Localization To Plasma Membrane Response To Peptide Positive Regulation Of Chemokine Production G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Membrane Raft Distribution Establishment Of Protein Localization To Membrane Recycling Endosome Organelle Localization By Membrane Tethering Membrane Raft Localization