MFF and MPZL1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MFF	MPZL1
Description		mitochondrial fission factor	myelin protein zero like 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisome Synaptic Vesicle Membrane Cytoplasmic Vesicle Mitochondrial Membrane Protein-containing Complex Synapse	Plasma Membrane Focal Adhesion Cell Surface Membrane
	Molecular Function	Protein Binding Identical Protein Binding Protein Homodimerization Activity	Structural Molecule Activity Protein Binding
	Biological Process	Mitochondrial Fission Protein Targeting To Mitochondrion Mitochondrion Organization Peroxisome Fission Positive Regulation Of Mitochondrial Fission	Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell-cell Signaling
Pathways
Drugs
Diseases
GWAS		Intraocular pressure ( 29617998) Refractive astigmatism ( 30306274)	Alzheimer's disease (late onset) ( 22881374) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		107 interacting genes: ADIPOQ AGPAT4 AIG1 ANKRD46 APOD APOL2 AQP3 AQP6 ATP6V0B BET1 C14orf180 C1QL4 C3orf52 CD79A CDIPT CEND1 CLDN19 CMTM5 CNIH1 COL4A5 CTXN3 CXCL16 CYB5B CYBC1 DNM1L ERGIC3 FAM209A FAM210B FAM3C FATE1 FCER1G FDCSP FXYD6 GJB1 GKN1 GOSR2 GPR152 IGFBP5 JAGN1 LAT LHFPL5 LPAR3 MEOX2 MIP MMGT1 MOSPD3 MPZL1 MTNR1B NIPAL3 NRM NTS OPN1SW OPRM1 PLK3 PLLP PLN PLP1 RAET1L RETREG3 RHBDL1 SACM1L SEC11C SEC22A SEC22B SEC23A SERINC2 SHISAL1 SLC18A3 SLC35B1 SLC41A2 SLC7A1 SLC7A14 SLC7A8 SMIM1 STRIT1 STX7 STX8 TEX264 TFRC TM6SF1 TMEM128 TMEM140 TMEM14C TMEM201 TMEM218 TMEM229B TMEM237 TMEM254 TMEM42 TMEM60 TMEM86B TMEM88 TMEM97 TMX2 TRAF3 TRAF3IP3 TRAM1L1 TRARG1 TSPAN2 TSPAN33 TSPO2 UBC UNC50 UNC93B1 UPK1B VAMP4 ZFPL1	10 interacting genes: DOK7 EXOSC4 FBXO7 FHL3 MFF PTPN11 SRC STAT3 TRIM55 TRIM63
Entrez ID		56947	9019
HPRD ID		16653	05086
Ensembl ID		ENSG00000168958	ENSG00000197965
Uniprot IDs		A0A0A0MS29 A0A9H3ZVE5 A0A9L9PY92 H7C433 Q9GZY8	A8K5D4 O95297
PDB IDs			6IGO 6IGT 6IGW
Enriched GO Terms of Interacting Partners?		Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Protein Binding SNAP Receptor Activity SNARE Complex Golgi Membrane Mitochondrial Outer Membrane Endomembrane System Membrane Fusion Water Channel Activity Vesicle-mediated Transport Magnesium Ion Transmembrane Transporter Activity Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Magnesium Ion Transmembrane Transport Plasma Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Magnesium Ion Transport Organelle Fusion Transmembrane Transport Protein Localization To Plasma Membrane Membrane Organization Nuclear Inner Membrane Vesicle Fusion Regulation Of Protein Transport Cellular Localization Regulation Of Cellular Localization Water Transport Golgi Apparatus Organelle Membrane Fusion ER To Golgi Transport Vesicle Membrane Protein Localization To Cell Periphery Regulation Of ATPase-coupled Calcium Transmembrane Transporter Activity Cone Photoreceptor Outer Segment Chloride Channel Inhibitor Activity Inorganic Cation Transmembrane Transporter Activity Vesicle Organization Myelin Sheath Amino Acid Transmembrane Transporter Activity Negative Regulation Of Protein Transport Renal Water Transport Myeloid Cell Differentiation Neutrophil Differentiation Cobalt Ion Transport	Regulation Of Glycolytic Process Negative Regulation Of Neutrophil Activation Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Regulation Of Neutrophil Activation Neutrophil Activation Involved In Immune Response Interleukin-6-mediated Signaling Pathway Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Glycolytic Process Protein Kinase Binding Negative Regulation Of ATP Metabolic Process Neutrophil Activation Protein Targeting To Mitochondrion Astrocyte Differentiation Negative Regulation Of Leukocyte Activation Positive Regulation Of Intracellular Signal Transduction Negative Regulation Of Cell Activation Immune System Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of ATP Metabolic Process Negative Regulation Of Multicellular Organismal Process Positive Regulation Of Notch Signaling Pathway T Cell Costimulation Regulation Of Intracellular Signal Transduction Enzyme-linked Receptor Protein Signaling Pathway Ephrin Receptor Signaling Pathway Vasodilation Negative Regulation Of Cortisol Secretion Negative Regulation Of Growth Hormone Secretion Canonical NF-kappaB Signal Transduction Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Epidermal Growth Factor Receptor Signaling Pathway Myeloid Cell Development Protein-containing Complex Positive Regulation Of Phosphate Metabolic Process Regulation Of Small Molecule Metabolic Process Positive Regulation Of Small GTPase Mediated Signal Transduction Establishment Of Protein Localization To Mitochondrion Establishment Of Protein Localization To Organelle ERBB Signaling Pathway Post-translational Protein Modification Signaling Adaptor Activity Response To Interleukin-1 Regulation Of Cellular Component Organization Intestinal Epithelial Cell Migration Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation
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