PRL

Gene Name		prolactin
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region
	Molecular Function	Prolactin Receptor Binding Hormone Activity Protein Binding
	Biological Process	Cell Surface Receptor Signaling Pathway Female Pregnancy Lactation Cell Proliferation Regulation Of Multicellular Organism Growth Positive Regulation Of JAK-STAT Cascade JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Pathways		Amyloids Nuclear signaling by ERBB4 Cytokine Signaling in Immune system Signaling by ERBB4 Prolactin receptor signaling Growth hormone receptor signaling
Drugs
Diseases
GWAS		Paget's disease ( 21623375) Pulmonary function (interaction) ( 23284291)
Protein-protein Interactions		3 interactors: PPIB PRLR UBQLN4
Entrez ID		5617
HPRD ID		07180
Ensembl ID		ENSG00000172179
Uniprot IDs		P01236 Q5THQ0
PDB IDs		1RW5 2Q98 3D48 3EW3 3MZG 3N06 3N0P 3NCB 3NCC 3NCE 3NCF 3NPZ
Enriched GO Terms of Interacting Partners?		Activation Of JAK2 Kinase Activity Prolactin Signaling Pathway Positive Regulation By Host Of Viral Genome Replication Positive Regulation By Host Of Viral Process Activation Of Janus Kinase Activity Activation Of Transmembrane Receptor Protein Tyrosine Kinase Activity Prostate Gland Growth Mammary Gland Epithelial Cell Differentiation Positive Regulation Of Viral Genome Replication JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus Interaction With Symbiont Peptidyl-amino Acid Modification Response To Growth Hormone Mammary Gland Alveolus Development Mammary Gland Lobule Development
Tagcloud ?		adulthood already autocrine cloned gh hyperplasia islet islets lactogen man mitotic motifs mutational neogenesis pancreas pl place placental preadipocyte pref pregnancy prolactin pronounced putative rodents stat1 stat5 take ways