CAPZB and MRPL20

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CAPZB	MRPL20
Gene Name		capping protein (actin filament) muscle Z-line, beta	mitochondrial ribosomal protein L20
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Actin Filament F-actin Capping Protein Complex Actin Cytoskeleton Sarcomere Actin Cortical Patch Extracellular Vesicular Exosome WASH Complex	Mitochondrial Inner Membrane Mitochondrial Ribosome
	Molecular Function	Actin Binding Actin Filament Binding	Structural Constituent Of Ribosome Protein Binding RRNA Binding Poly(A) RNA Binding
	Biological Process	Movement Of Cell Or Subcellular Component Cytoskeleton Organization Blood Coagulation Regulation Of Lamellipodium Assembly Regulation Of Cell Morphogenesis Actin Cytoskeleton Organization Barbed-end Actin Filament Capping Negative Regulation Of Filopodium Assembly	Organelle Organization Mitochondrial Translation Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways		Factors involved in megakaryocyte development and platelet production	Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS		Crohn's disease and psoriasis ( 22482804) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid volume ( 21565293)
Protein-Protein Interactions		7 interactors: BCCIP HSPA8 MRPL20 MTPN PTN RPP14 VHL	10 interactors: ACP1 APP CALM2 CAPZB DUSP23 EPS8 ITSN1 OXA1L TP53BP2 USP13
Entrez ID		832	55052
HPRD ID		11872	14746
Ensembl ID		ENSG00000077549	ENSG00000242485
Uniprot IDs		B1AK85 B1AK88 B4DWA6 P47756 Q7L4N0	B7Z746 Q9BYC9
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Fibril Organization Regulation Of Fibril Organization Regulation Of Barbed-end Actin Filament Capping Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Protein Complex Disassembly Clathrin Coat Disassembly Protein Complex Disassembly Neuroendocrine Cell Differentiation	Barbed-end Actin Filament Capping Actin Filament Capping Negative Regulation Of Actin Filament Depolymerization Regulation Of Signal Transduction Regulation Of Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Platelet Degranulation Regulation Of Oxidoreductase Activity Negative Regulation Of Protein Polymerization Blood Coagulation Regulation Of Signaling Negative Regulation Of Protein Complex Disassembly Hemostasis Response To Radiation Regulation Of Protein Depolymerization Synaptic Growth At Neuromuscular Junction Mitochondrial Proton-transporting ATP Synthase Complex Assembly Adult Locomotory Behavior Regulation Of Protein Complex Disassembly Negative Regulation Of Protein Complex Assembly Actin Polymerization-dependent Cell Motility Collateral Sprouting In Absence Of Injury Nervous System Development Regulation Of Body Fluid Levels Proton-transporting ATP Synthase Complex Assembly Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Wound Healing Negative Regulation Of Cytoskeleton Organization Collateral Sprouting Axon Midline Choice Point Recognition Epidermal Growth Factor Receptor Signaling Pathway Adult Behavior ERBB Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Peptidyl-tyrosine Dephosphorylation Regulation Of Actin Filament Polymerization Movement Of Cell Or Subcellular Component Negative Regulation Of Filopodium Assembly Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of High Voltage-gated Calcium Channel Activity Response To Wounding Exit From Mitosis Axon Choice Point Recognition Platelet Activation Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Neurotrophin TRK Receptor Signaling Pathway Negative Regulation Of ATPase Activity
Tagcloud ?		actin align apolar capping capza2 cdnas chicken conservation cosedimentation divergence diverges gelsolin homologs leucines mapped monomer outside p36 polar portion q31 regularly severing shares spaced substitutions subunit	capza1 cgh cghs cnv coherent col20a1 csde1 csnk1e dennd2d derive discerning discriminative gpr18 han hbxip identifiable ikzf1 mcoln2 microarrays rcan3 rwdd3 scrn1 signatures statuses supervised taiwanese trim45 wars2 zmym6
Tagcloud (Difference) ?		actin align apolar capping capza2 cdnas chicken conservation cosedimentation divergence diverges gelsolin homologs leucines mapped monomer outside p36 polar portion q31 regularly severing shares spaced substitutions subunit	capza1 cgh cghs cnv coherent col20a1 csde1 csnk1e dennd2d derive discerning discriminative gpr18 han hbxip identifiable ikzf1 mcoln2 microarrays rcan3 rwdd3 scrn1 signatures statuses supervised taiwanese trim45 wars2 zmym6
Tagcloud (Intersection) ?