CAPZB

Gene Name		capping protein (actin filament) muscle Z-line, beta
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Cytoskeleton Actin Filament F-actin Capping Protein Complex Actin Cytoskeleton Sarcomere Actin Cortical Patch Extracellular Vesicular Exosome WASH Complex
	Molecular Function	Actin Binding Actin Filament Binding
	Biological Process	Movement Of Cell Or Subcellular Component Cytoskeleton Organization Blood Coagulation Regulation Of Lamellipodium Assembly Regulation Of Cell Morphogenesis Actin Cytoskeleton Organization Barbed-end Actin Filament Capping Negative Regulation Of Filopodium Assembly
Pathways		Factors involved in megakaryocyte development and platelet production
Drugs
Diseases
GWAS		Crohn's disease and psoriasis ( 22482804) Thyroid function ( 22494929) Thyroid hormone levels ( 23408906) Thyroid volume ( 21565293)
Protein-protein Interactions		7 interactors: BCCIP HSPA8 MRPL20 MTPN PTN RPP14 VHL
Entrez ID		832
HPRD ID		11872
Ensembl ID		ENSG00000077549
Uniprot IDs		B1AK85 B1AK88 B4DWA6 P47756 Q7L4N0
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Fibril Organization Regulation Of Fibril Organization Regulation Of Barbed-end Actin Filament Capping Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Cellular Protein Complex Disassembly Clathrin Coat Disassembly Protein Complex Disassembly Neuroendocrine Cell Differentiation
Tagcloud ?		actin align apolar capping capza2 cdnas chicken conservation cosedimentation divergence diverges gelsolin homologs leucines mapped monomer outside p36 polar portion q31 regularly severing shares spaced substitutions subunit