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PRPSAP1 and PRPS1
Number of citations of the paper that reports this interaction (PMID
9366267
)
0
Data Source:
HPRD
(in vivo, in vitro)
PRPSAP1
PRPS1
Gene Name
phosphoribosyl pyrophosphate synthetase-associated protein 1
phosphoribosyl pyrophosphate synthetase 1
Image
Gene Ontology Annotations
Cellular Component
Ribose Phosphate Diphosphokinase Complex
Cytosol
Molecular Function
Magnesium Ion Binding
Ribose Phosphate Diphosphokinase Activity
Enzyme Inhibitor Activity
Kinase Binding
Magnesium Ion Binding
Ribose Phosphate Diphosphokinase Activity
ATP Binding
Kinase Activity
Protein Homodimerization Activity
Biological Process
Nucleobase-containing Compound Metabolic Process
Nucleotide Biosynthetic Process
Negative Regulation Of Kinase Activity
Carbohydrate Metabolic Process
5-phosphoribose 1-diphosphate Biosynthetic Process
Purine Nucleobase Metabolic Process
Purine Nucleotide Biosynthetic Process
Pyrimidine Nucleotide Biosynthetic Process
Nervous System Development
Ribonucleoside Monophosphate Biosynthetic Process
Pathogenesis
Phosphorylation
Urate Biosynthetic Process
Small Molecule Metabolic Process
Hypoxanthine Biosynthetic Process
Pathways
5-Phosphoribose 1-diphosphate biosynthesis
Myoclonic epilepsy of Lafora
Glycogen storage diseases
Metabolism of carbohydrates
Drugs
Diseases
GWAS
Urate levels (
23263486
)
Protein-Protein Interactions
5 interactors:
DDX19B
MAPK1
PLEKHF2
PRPS1
PRPS2
5 interactors:
GORASP2
PRPS2
PRPSAP1
SPG21
SUMO4
Entrez ID
5635
5631
HPRD ID
03151
02413
Ensembl ID
ENSG00000161542
ENSG00000147224
Uniprot IDs
Q14558
B7ZB02
P60891
PDB IDs
2C4K
2H06
2H07
2H08
2HCR
3EFH
3S5J
4F8E
Enriched GO Terms of Interacting Partners
?
5-phosphoribose 1-diphosphate Biosynthetic Process
Ribonucleoside Monophosphate Biosynthetic Process
Nucleoside Monophosphate Biosynthetic Process
Nucleobase-containing Small Molecule Metabolic Process
MAPK Import Into Nucleus
Urate Biosynthetic Process
Purine Nucleotide Biosynthetic Process
Ribose Phosphate Biosynthetic Process
Regulation Of Golgi Inheritance
Hypoxanthine Metabolic Process
Hypoxanthine Biosynthetic Process
Caveolin-mediated Endocytosis
Cytosine Metabolic Process
AMP Biosynthetic Process
Nucleocytoplasmic Transport
Nuclear Transport
Regulation Of Golgi Organization
Nucleotide Biosynthetic Process
Purine Nucleotide Metabolic Process
Ribose Phosphate Metabolic Process
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Protein Transport
Establishment Of Protein Localization
Urate Metabolic Process
Regulation Of Early Endosome To Late Endosome Transport
Purine Nucleobase Biosynthetic Process
AMP Metabolic Process
Positive Regulation Of Peptidyl-threonine Phosphorylation
ERK1 And ERK2 Cascade
Phosphorylation
Protein Localization
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Mammary Gland Epithelial Cell Proliferation
Growth Hormone Receptor Signaling Pathway
Nucleotide Metabolic Process
Cellular Response To Growth Hormone Stimulus
Labyrinthine Layer Blood Vessel Development
Response To Epidermal Growth Factor
Regulation Of Cellular Response To Heat
Pyrimidine Nucleobase Metabolic Process
Cytoplasmic Transport
Placenta Blood Vessel Development
Small Molecule Metabolic Process
Lipopolysaccharide-mediated Signaling Pathway
B Cell Receptor Signaling Pathway
Response To Growth Hormone
Purine Nucleobase Metabolic Process
5-phosphoribose 1-diphosphate Biosynthetic Process
AMP Biosynthetic Process
Nucleotide Biosynthetic Process
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Tagcloud (Intersection)
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