PRPSAP1 and DDX19B

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		PRPSAP1	DDX19B
Gene Name		phosphoribosyl pyrophosphate synthetase-associated protein 1	DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
Image
Gene Ontology Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex	Nuclear Envelope Nuclear Pore Cytoplasm Membrane Nuclear Membrane Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Kinase Binding	RNA Binding Helicase Activity ATP Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Nucleotide Biosynthetic Process Negative Regulation Of Kinase Activity	MRNA Export From Nucleus Protein Transport
Pathways
Drugs
Diseases
GWAS		Urate levels ( 23263486)
Protein-Protein Interactions		5 interactors: DDX19B MAPK1 PLEKHF2 PRPS1 PRPS2	13 interactors: APP B3GALT4 DCK GNB2L1 IKBKG MIF4GD NUP214 POT1 PRPSAP1 RWDD2B SKP1 TERF1 XPO7
Entrez ID		5635	11269
HPRD ID		03151	05781
Ensembl ID		ENSG00000161542	ENSG00000157349
Uniprot IDs		Q14558	B4DL69 Q9UMR2
PDB IDs		2C4K	3EWS 3FHC 3FHT 3FMO 3FMP 3G0H
Enriched GO Terms of Interacting Partners?		5-phosphoribose 1-diphosphate Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process MAPK Import Into Nucleus Urate Biosynthetic Process Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Regulation Of Golgi Inheritance Hypoxanthine Metabolic Process Hypoxanthine Biosynthetic Process Caveolin-mediated Endocytosis Cytosine Metabolic Process AMP Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Regulation Of Golgi Organization Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Protein Transport Establishment Of Protein Localization Urate Metabolic Process Regulation Of Early Endosome To Late Endosome Transport Purine Nucleobase Biosynthetic Process AMP Metabolic Process Positive Regulation Of Peptidyl-threonine Phosphorylation ERK1 And ERK2 Cascade Phosphorylation Protein Localization JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Mammary Gland Epithelial Cell Proliferation Growth Hormone Receptor Signaling Pathway Nucleotide Metabolic Process Cellular Response To Growth Hormone Stimulus Labyrinthine Layer Blood Vessel Development Response To Epidermal Growth Factor Regulation Of Cellular Response To Heat Pyrimidine Nucleobase Metabolic Process Cytoplasmic Transport Placenta Blood Vessel Development Small Molecule Metabolic Process Lipopolysaccharide-mediated Signaling Pathway B Cell Receptor Signaling Pathway Response To Growth Hormone Purine Nucleobase Metabolic Process	Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Transferase Activity Regulation Of Telomerase Activity Negative Regulation Of Catalytic Activity Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of DNA Biosynthetic Process Regulation Of Catalytic Activity Telomere Maintenance Via Telomere Lengthening Viral Process Protein Export From Nucleus Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Regulation Of Translation Positive Regulation Of Proteolysis Regulation Of Protein Tyrosine Kinase Activity Regulation Of Protein Metabolic Process Positive Regulation Of DNA Strand Elongation Telomere Maintenance Regulation Of Kinase Activity Positive Regulation Of Catalytic Activity Negative Regulation Of Chromosome Organization Regulation Of Protein Catabolic Process Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Positive Regulation Of CAMP Catabolic Process Regulation Of Cell Cycle Negative Regulation Of DNA Metabolic Process Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Telomere Formation Via Telomerase Collateral Sprouting In Absence Of Injury Telomeric Loop Formation Age-dependent Telomere Shortening Posttranscriptional Regulation Of Gene Expression Positive Regulation Of Mitotic Cell Cycle Nuclear Export MRNA Transport G2/M Transition Of Mitotic Cell Cycle Telomere Maintenance Via Telomere Shortening Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of DNA Replication Positive Regulation Of Cellular Protein Metabolic Process RNA Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?