PRPSAP1 and PRPS2

Number of citations of the paper that reports this interaction (PMID 9366267)
0

Data Source:
HPRD (in vitro, in vivo)

		PRPSAP1	PRPS2
Gene Name		phosphoribosyl pyrophosphate synthetase-associated protein 1	phosphoribosyl pyrophosphate synthetase 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex	Ribose Phosphate Diphosphokinase Complex Extracellular Vesicular Exosome
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Kinase Binding	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity ATP Binding AMP Binding Kinase Activity GDP Binding Carbohydrate Binding Protein Homodimerization Activity ADP Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Nucleotide Biosynthetic Process Negative Regulation Of Kinase Activity	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process AMP Biosynthetic Process Phosphorylation Organ Regeneration
Pathways			5-Phosphoribose 1-diphosphate biosynthesis Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS		Urate levels ( 23263486)
Protein-Protein Interactions		5 interactors: DDX19B MAPK1 PLEKHF2 PRPS1 PRPS2	4 interactors: NOTCH2NL PRPS1 PRPSAP1 WDYHV1
Entrez ID		5635	5634
HPRD ID		03151	02414
Ensembl ID		ENSG00000161542	ENSG00000101911
Uniprot IDs		Q14558	P11908
PDB IDs		2C4K
Enriched GO Terms of Interacting Partners?		5-phosphoribose 1-diphosphate Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process MAPK Import Into Nucleus Urate Biosynthetic Process Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Regulation Of Golgi Inheritance Hypoxanthine Metabolic Process Hypoxanthine Biosynthetic Process Caveolin-mediated Endocytosis Cytosine Metabolic Process AMP Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Regulation Of Golgi Organization Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Protein Transport Establishment Of Protein Localization Urate Metabolic Process Regulation Of Early Endosome To Late Endosome Transport Purine Nucleobase Biosynthetic Process AMP Metabolic Process Positive Regulation Of Peptidyl-threonine Phosphorylation ERK1 And ERK2 Cascade Phosphorylation Protein Localization JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Mammary Gland Epithelial Cell Proliferation Growth Hormone Receptor Signaling Pathway Nucleotide Metabolic Process Cellular Response To Growth Hormone Stimulus Labyrinthine Layer Blood Vessel Development Response To Epidermal Growth Factor Regulation Of Cellular Response To Heat Pyrimidine Nucleobase Metabolic Process Cytoplasmic Transport Placenta Blood Vessel Development Small Molecule Metabolic Process Lipopolysaccharide-mediated Signaling Pathway B Cell Receptor Signaling Pathway Response To Growth Hormone Purine Nucleobase Metabolic Process	Urate Biosynthetic Process 5-phosphoribose 1-diphosphate Biosynthetic Process Hypoxanthine Metabolic Process Hypoxanthine Biosynthetic Process Nucleotide Biosynthetic Process Urate Metabolic Process Purine Nucleobase Biosynthetic Process Nucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Purine Nucleobase Metabolic Process
Tagcloud ?			00e 19e 40e 47e asian autosomes cohorts contributors erythematosus gwas han intriguing irak1 l1cam mecp2 naa10 predisposition predominance prototype prototypic replicated replicating rs1059702 rs17422 rs2071128 rs7062536 sle tmem187 xp22
Tagcloud (Difference) ?			00e 19e 40e 47e asian autosomes cohorts contributors erythematosus gwas han intriguing irak1 l1cam mecp2 naa10 predisposition predominance prototype prototypic replicated replicating rs1059702 rs17422 rs2071128 rs7062536 sle tmem187 xp22
Tagcloud (Intersection) ?