PRPSAP1

Gene Name		phosphoribosyl pyrophosphate synthetase-associated protein 1
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Gene Ontology Annotations	Cellular Component	Ribose Phosphate Diphosphokinase Complex
	Molecular Function	Magnesium Ion Binding Ribose Phosphate Diphosphokinase Activity Enzyme Inhibitor Activity Kinase Binding
	Biological Process	Nucleobase-containing Compound Metabolic Process Nucleotide Biosynthetic Process Negative Regulation Of Kinase Activity
Pathways
Drugs
Diseases
GWAS		Urate levels ( 23263486)
Protein-protein Interactions		5 interactors: DDX19B MAPK1 PLEKHF2 PRPS1 PRPS2
Entrez ID		5635
HPRD ID		03151
Ensembl ID		ENSG00000161542
Uniprot IDs		Q14558
PDB IDs		2C4K
Enriched GO Terms of Interacting Partners?		5-phosphoribose 1-diphosphate Biosynthetic Process Ribonucleoside Monophosphate Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Nucleobase-containing Small Molecule Metabolic Process MAPK Import Into Nucleus Urate Biosynthetic Process Purine Nucleotide Biosynthetic Process Ribose Phosphate Biosynthetic Process Regulation Of Golgi Inheritance Hypoxanthine Metabolic Process Hypoxanthine Biosynthetic Process Caveolin-mediated Endocytosis Cytosine Metabolic Process AMP Biosynthetic Process Nucleocytoplasmic Transport Nuclear Transport Regulation Of Golgi Organization Nucleotide Biosynthetic Process Purine Nucleotide Metabolic Process Ribose Phosphate Metabolic Process Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus Protein Transport Establishment Of Protein Localization Urate Metabolic Process Regulation Of Early Endosome To Late Endosome Transport Purine Nucleobase Biosynthetic Process AMP Metabolic Process Positive Regulation Of Peptidyl-threonine Phosphorylation ERK1 And ERK2 Cascade Phosphorylation Protein Localization JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Mammary Gland Epithelial Cell Proliferation Growth Hormone Receptor Signaling Pathway Nucleotide Metabolic Process Cellular Response To Growth Hormone Stimulus Labyrinthine Layer Blood Vessel Development Response To Epidermal Growth Factor Regulation Of Cellular Response To Heat Pyrimidine Nucleobase Metabolic Process Cytoplasmic Transport Placenta Blood Vessel Development Small Molecule Metabolic Process Lipopolysaccharide-mediated Signaling Pathway B Cell Receptor Signaling Pathway Response To Growth Hormone Purine Nucleobase Metabolic Process
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