PRPSAP1

Description		phosphoribosyl pyrophosphate synthetase associated protein 1
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GO Annotations	Cellular Component	Cytoplasm
	Molecular Function	Magnesium Ion Binding Enzyme Inhibitor Activity Protein Binding Enzyme Regulator Activity Identical Protein Binding
	Biological Process	5-phosphoribose 1-diphosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process Nucleotide Biosynthetic Process
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) High-grade serous ovarian cancer ( 31469419) Nontraumatic osteonecrosis of the femoral head ( 32701715) Red cell distribution width ( 32888494) Reticulocyte count ( 32888494) Urate levels ( 23263486)
Interacting Genes		8 interacting genes: CAPN7 DDX19B MAGOHB MAPK1 PLEKHF2 PRPS1 PRPS2 UBE2I
Entrez ID		5635
HPRD ID		03151
Ensembl ID		ENSG00000161542
Uniprot IDs		B4DP31 Q14558
PDB IDs		2C4K
Enriched GO Terms of Interacting Partners?		Ribose Phosphate Diphosphokinase Activity 5-phosphoribose 1-diphosphate Biosynthetic Process Nuclear Export ATP Binding Ribonucleoside Monophosphate Biosynthetic Process Nucleoside Monophosphate Biosynthetic Process Nuclear Transport Nucleocytoplasmic Transport Pyrimidine-containing Compound Metabolic Process Nucleotide Binding Ribose Phosphate Diphosphokinase Complex Nucleoside Monophosphate Metabolic Process SUMO Conjugating Enzyme Activity MRNA Export From Nucleus RNA Export From Nucleus Nuclear Pore Cytosine Metabolic Process Urate Biosynthetic Process Interleukin-34-mediated Signaling Pathway Hypoxanthine Biosynthetic Process RING-like Zinc Finger Domain Binding Intracellular Transport MIT Domain Binding Exon-exon Junction Subcomplex Mago-y14 Nucleobase-containing Small Molecule Metabolic Process Caveolin-mediated Endocytosis Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of Golgi Inheritance Positive Regulation Of Macrophage Proliferation Positive Regulation Of Locomotion Kinase Activity Hypoxanthine Metabolic Process Ribose Phosphate Biosynthetic Process SUMO Ligase Complex Small Protein Activating Enzyme Binding HLH Domain Binding RNA Transport MRNA Transport Purine Nucleotide Biosynthetic Process Cardiac Neural Crest Cell Development Involved In Heart Development Trachea Formation Cellular Localization Establishment Of Localization In Cell Outer Ear Morphogenesis ERBB3 Signaling Pathway Positive Regulation Of Peptidyl-threonine Phosphorylation RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity ERBB2-ERBB3 Signaling Pathway Bergmann Glial Cell Differentiation
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