SLC7A10 and SLC3A2

Number of citations of the paper that reports this interaction (PubMedID 15458438)
0

Data Source:
HPRD (in vivo)

		SLC7A10	SLC3A2
Description		solute carrier family 7 member 10	solute carrier family 3 member 2
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane	Nucleoplasm Lysosome Lysosomal Membrane Plasma Membrane Basal Plasma Membrane Cell Surface Membrane Basolateral Plasma Membrane Apical Plasma Membrane Melanosome Neuronal Cell Body Apical Pole Of Neuron Synapse Extracellular Exosome Anchoring Junction Amino Acid Transport Complex
	Molecular Function	Protein Binding Organic Cation Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity Transmembrane Transporter Activity	Virus Receptor Activity RNA Binding Double-stranded RNA Binding Protein Binding Aromatic Amino Acid Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-leucine Transmembrane Transporter Activity Protein Homodimerization Activity Cadherin Binding Protein Heterodimerization Activity Exogenous Protein Binding
	Biological Process	Amino Acid Transport Neutral Amino Acid Transport Glycine Transport L-serine Transport D-alanine Transmembrane Transport D-serine Transmembrane Transport Transmembrane Transport Positive Regulation Of Synaptic Transmission, Glycinergic L-alpha-amino Acid Transmembrane Transport Negative Regulation Of Brown Fat Cell Differentiation	Carbohydrate Metabolic Process Calcium Ion Transport Amino Acid Transport Isoleucine Transport L-leucine Transport Methionine Transport Phenylalanine Transport Proline Transport Tryptophan Transport Tyrosine Transport Valine Transport Response To Exogenous DsRNA Symbiont Entry Into Host Cell Thyroid Hormone Transport L-histidine Transport L-leucine Import Across Plasma Membrane L-alanine Import Across Plasma Membrane
Pathways		Basigin interactions Amino acid transport across the plasma membrane	Basigin interactions Amino acid transport across the plasma membrane Defective SLC7A7 causes lysinuric protein intolerance (LPI) Tryptophan catabolism
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 30013184) Asthma ( 34103634 30929738 32296059 31959851 31361310 31619474) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eosinophil count ( 32888494) Mastocytosis (KIT D816V positive) ( 33421400) Medication use (adrenergics, inhalants) ( 31015401) Medication use (glucocorticoids) ( 31015401) Multiple sclerosis ( 31604244) Red blood cell count ( 29403010) Triglyceride levels ( 32203549) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) White blood cell count (basophil) ( 29403010)	Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		3 interacting genes: APPBP2 CFTR SLC3A2	18 interacting genes: CCR4 CEBPA EBP EGFR GPR37 HNRNPD ICAM1 ITGB1 KLHL20 MTNR1B NPSR1 SLC7A10 SLC7A11 SLC7A5 SLC7A7 SLC7A8 TLCD3A VHL
Entrez ID		56301	6520
HPRD ID		12137	01148
Ensembl ID		ENSG00000130876	ENSG00000168003
Uniprot IDs		K7EK24 Q9NS82	P08195
PDB IDs		8QEY 8WNS 8WNT 8WNY	2DH2 2DH3 6IRS 6IRT 6JMQ 6JMR 6S8V 7B00 7CCS 7CMH 7CMI 7DF1 7DSK 7DSL 7DSN 7DSQ 7EPZ 7P9U 7P9V 8A6L 8G0M 8IDA 8J8L 8J8M 8KDD 8KDF 8KDG 8KDH 8KDI 8KDJ 8KDN 8KDO 8KDP 8QEY 8WNS 8WNT 8WNY 8X0W 8XPU 8YLP
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Basolateral Plasma Membrane Apical Pole Of Neuron Isoleucine Transport L-histidine Transport Exogenous Protein Binding Methionine Transport L-leucine Transmembrane Transporter Activity L-leucine Import Across Plasma Membrane Phenylalanine Transport Amino Acid Transport Complex L-alanine Transmembrane Transport Aromatic Amino Acid Transmembrane Transporter Activity Valine Transport Tryptophan Transport L-alanine Import Across Plasma Membrane Tyrosine Transport Positive Regulation Of Tooth Mineralization L-alanine Transmembrane Transporter Activity Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation L-alanine Transport Amelogenesis L-leucine Transport Proline Transport Organic Anion Transport ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Aromatic Amino Acid Transport Branched-chain Amino Acid Transport Thyroid Hormone Transport Apical Plasma Membrane Lysosomal Membrane Regulation Of Immature T Cell Proliferation In Thymus Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Alanine Transport Sulfur Amino Acid Transport Cellular Response To Forskolin Response To Forskolin	L-amino Acid Transmembrane Transporter Activity Neutral Amino Acid Transport L-alpha-amino Acid Transmembrane Transport L-amino Acid Transport Amino Acid Transmembrane Transport Negative Regulation Of Programmed Cell Death Amino Acid Transport Branched-chain Amino Acid Transport L-leucine Transport Organic Acid Transmembrane Transport Carboxylic Acid Transmembrane Transport Alanine Transport Neutral L-amino Acid Transmembrane Transporter Activity Transmembrane Transporter Activity Negative Regulation Of Apoptotic Process Organic Cation Transport L-leucine Import Across Plasma Membrane Microvillus Membrane Liver Development Response To Amino Acid Regulation Of Apoptotic Process Amino Acid Import Across Plasma Membrane Carboxylic Acid Transport Organic Acid Transport Valine Transport Regulation Of Programmed Cell Death L-leucine Transmembrane Transporter Activity Tryptophan Transport Plasma Membrane Thyroid Hormone Transmembrane Transporter Activity Organic Anion Transport Negative Regulation Of Catabolic Process Basal Plasma Membrane Aromatic Amino Acid Transport Thyroid Hormone Transport Organic Cation Transmembrane Transporter Activity Animal Organ Development Glycine Transport Negative Regulation Of Vasoconstriction Cellular Response To Amino Acid Stimulus Virus Receptor Activity Sulfur Amino Acid Transport Basolateral Plasma Membrane Vascular Process In Circulatory System Neuropeptide Signaling Pathway Learning Or Memory Gland Development Neuropeptide Receptor Activity Basic Amino Acid Transport Response To Cytokine
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