SLC7A10

Description		solute carrier family 7 member 10
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GO Annotations	Cellular Component	Plasma Membrane Membrane
	Molecular Function	Protein Binding Organic Cation Transmembrane Transporter Activity Neutral L-amino Acid Transmembrane Transporter Activity L-amino Acid Transmembrane Transporter Activity L-serine Transmembrane Transporter Activity Transmembrane Transporter Activity
	Biological Process	Amino Acid Transport Neutral Amino Acid Transport Glycine Transport L-serine Transport D-alanine Transmembrane Transport D-serine Transmembrane Transport Transmembrane Transport Positive Regulation Of Synaptic Transmission, Glycinergic L-alpha-amino Acid Transmembrane Transport Negative Regulation Of Brown Fat Cell Differentiation
Pathways		Basigin interactions Amino acid transport across the plasma membrane
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406 29785011) Allergic rhinitis ( 30013184) Asthma ( 34103634 30929738 32296059 31959851 31361310 31619474) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Eosinophil count ( 32888494) Mastocytosis (KIT D816V positive) ( 33421400) Medication use (adrenergics, inhalants) ( 31015401) Medication use (glucocorticoids) ( 31015401) Multiple sclerosis ( 31604244) Red blood cell count ( 29403010) Triglyceride levels ( 32203549) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) White blood cell count (basophil) ( 29403010)
Novel Interacting Genes		1 novel interacting genes: TNFRSF9
Interacting Genes		3 interacting genes: APPBP2 CFTR SLC3A2
Entrez ID		56301
HPRD ID		12137
Ensembl ID		ENSG00000130876
Uniprot IDs		K7EK24 Q9NS82
PDB IDs		8QEY 8WNS 8WNT 8WNY
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Anion Channel Activity Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Basolateral Plasma Membrane Apical Pole Of Neuron Isoleucine Transport L-histidine Transport Exogenous Protein Binding Methionine Transport L-leucine Transmembrane Transporter Activity L-leucine Import Across Plasma Membrane Phenylalanine Transport Amino Acid Transport Complex L-alanine Transmembrane Transport Aromatic Amino Acid Transmembrane Transporter Activity Valine Transport Tryptophan Transport L-alanine Import Across Plasma Membrane Tyrosine Transport Positive Regulation Of Tooth Mineralization L-alanine Transmembrane Transporter Activity Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Bicarbonate Transmembrane Transporter Activity Intracellular PH Elevation L-alanine Transport Amelogenesis L-leucine Transport Proline Transport Organic Anion Transport ATPase-coupled Inorganic Anion Transmembrane Transporter Activity Aromatic Amino Acid Transport Branched-chain Amino Acid Transport Thyroid Hormone Transport Apical Plasma Membrane Lysosomal Membrane Regulation Of Immature T Cell Proliferation In Thymus Regulation Of Monoatomic Anion Transport Epithelial Fluid Transport Golgi-associated Vesicle Membrane Alanine Transport Sulfur Amino Acid Transport Cellular Response To Forskolin Response To Forskolin
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