RNF20 and AMOTL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RNF20	AMOTL2
Gene Name		ring finger protein 20, E3 ubiquitin protein ligase	angiomotin like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Nucleolus HULC Complex	Cytosol Tight Junction Apical Plasma Membrane Cytoplasmic Vesicle Recycling Endosome
	Molecular Function	P53 Binding Chromatin Binding Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Binding Histone Binding	Protein Binding Identical Protein Binding
	Biological Process	Protein Polyubiquitination Regulation Of Transcription, DNA-templated Ubiquitin-dependent Protein Catabolic Process Histone Monoubiquitination Negative Regulation Of Cell Migration Positive Regulation Of Histone Methylation Histone H2B Ubiquitination Positive Regulation Of Transcription, DNA-templated	Wnt Signaling Pathway Hippo Signaling
Pathways			Signaling by Hippo
Drugs
Diseases
GWAS
Protein-Protein Interactions		22 interactors: AMOTL2 ATM CDC73 HIST1H2BB HIST2H2AA3 HIST2H2AC HIST2H2BE HIST2H3C HIST2H4A HTT ITSN2 MSL1 PA2G4 PAF1 SMURF2 UBC UBE2A UBE2B UBE2E1 USHBP1 WAC ZDHHC17	52 interactors: BLZF1 BRMS1L CARD9 CCHCR1 CDR2 CYTH4 DDIT3 DYNLL1 EIF4E2 FAM184A FXR2 GCC1 GNG11 GNG5 GOLGA2 GSTM5 KRT13 KRT15 KRT19 KRT20 KRT31 KRT38 KRTAP10-5 KRTAP4-2 LMO4 MAD1L1 MAGEA4 MAGOHB MFAP1 MPP1 MTMR6 MYO5B NDC80 NFIL3 PSMC3 RAD51D RALBP1 RASSF5 RNF20 RNF40 SH3RF2 SMARCE1 SP100 SPAG5 SPP1 THRA TMCC2 TRAF2 TRIM27 WDYHV1 ZBED1 ZGPAT
Entrez ID		56254	51421
HPRD ID		07410	16485
Ensembl ID		ENSG00000155827	ENSG00000114019
Uniprot IDs		Q5VTR2	Q9Y2J4
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone Ubiquitination Chromatin Organization Histone Modification Histone H2B Ubiquitination Chromosome Organization Protein Monoubiquitination Chromatin Modification Histone Monoubiquitination Protein Ubiquitination Protein Modification By Small Protein Conjugation Negative Regulation Of Cellular Metabolic Process Cell Cycle Negative Regulation Of Transcription, DNA-templated Organelle Organization Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Protein Modification Process Chromatin Silencing Protein K48-linked Ubiquitination Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Gene Expression Regulation Of Cell Cycle Negative Regulation Of Biosynthetic Process Protein Catabolic Process Protein Polyubiquitination Cell Cycle Process Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process G1 DNA Damage Checkpoint Negative Regulation Of Cell Cycle Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Mitotic Cell Cycle Negative Regulation Of Cellular Protein Catabolic Process Cell Cycle Checkpoint Regulation Of Cell Cycle Phase Transition Regulation Of Cell Cycle Process DNA Methylation On Cytosine Negative Regulation Of Myeloid Cell Differentiation Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Negative Regulation Of Chromosome Organization Positive Regulation Of Signal Transduction Cellular Macromolecule Catabolic Process Proteasomal Protein Catabolic Process Cellular Protein Metabolic Process Histone H2A Ubiquitination Positive Regulation Of MRNA 3'-end Processing Chromatin Silencing At RDNA	Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Protein Localization Histone H2B Ubiquitination Regulation Of Cellular Localization Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Protein Polyubiquitination Mitotic Cell Cycle Organelle Organization Chromosome Organization Protein Ubiquitination Histone Monoubiquitination Negative Regulation Of Viral Transcription Cell Cycle Negative Regulation Of Transcription, DNA-templated Protein Modification By Small Protein Conjugation Regulation Of Establishment Of Protein Localization Protein K63-linked Ubiquitination Histone Ubiquitination Regulation Of Transcription From RNA Polymerase II Promoter Protein Trimerization Negative Regulation Of Determination Of Dorsal Identity Regulation Of Metaphase Plate Congression Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Protein Metabolic Process Response To Organic Substance Cellular Response To Glucagon Stimulus
Tagcloud ?		abundance coincide contributions di dot1l drives dynamic e3 employ evolutionarily exhibit garnered h2b h2bub1 h3k4me2 h3k79me2 implicate lysines mitosis mitotic normally overlooked patterning ptm reaches requisite rnai stability virtually	actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Difference) ?		abundance coincide contributions di dot1l drives dynamic e3 employ evolutionarily exhibit garnered h2b h2bub1 h3k4me2 h3k79me2 implicate lysines mitosis mitotic normally overlooked patterning ptm reaches requisite rnai stability virtually	actin alanine amots angiomotin collectively consensus contain core dissociation endogenously exogenous filaments hippo hxrxxs lats1 lats2 mapping mediate members mimic negatively phospho promoted s175a s175d serine taz yap
Tagcloud (Intersection) ?