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RNF20 and UBE2B
Number of citations of the paper that reports this interaction (PMID
19410543
)
102
Data Source:
BioGRID
(enzymatic study)
RNF20
UBE2B
Gene Name
ring finger protein 20, E3 ubiquitin protein ligase
ubiquitin-conjugating enzyme E2B
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Ubiquitin Ligase Complex
Nucleus
Nucleoplasm
Nucleolus
HULC Complex
Chromatin
Nuclear Chromatin
XY Body
Nucleus
Replication Fork
Cytoplasm
Plasma Membrane
HULC Complex
Molecular Function
P53 Binding
Chromatin Binding
Transcription Coactivator Activity
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Ligase Activity
Ubiquitin Protein Ligase Binding
Histone Binding
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ligase Activity
Ubiquitin-like Protein Transferase Activity
Ubiquitin Protein Ligase Binding
Ubiquitin Protein Ligase Activity
Biological Process
Protein Polyubiquitination
Regulation Of Transcription, DNA-templated
Ubiquitin-dependent Protein Catabolic Process
Histone Monoubiquitination
Negative Regulation Of Cell Migration
Positive Regulation Of Histone Methylation
Histone H2B Ubiquitination
Positive Regulation Of Transcription, DNA-templated
Protein Polyubiquitination
Response To Hypoxia
In Utero Embryonic Development
DNA Repair
Postreplication Repair
Maintenance Of Chromatin Silencing
Ubiquitin-dependent Protein Catabolic Process
Protein Monoubiquitination
Cellular Response To DNA Damage Stimulus
Spermatogenesis
Sperm Axoneme Assembly
Response To UV
Positive Regulation Of Reciprocal Meiotic Recombination
Protein Ubiquitination
Cellular Response To Insulin Stimulus
Negative Regulation Of Histone Phosphorylation
Histone H2A Ubiquitination
Response To Drug
Negative Regulation Of Apoptotic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of CAMP-mediated Signaling
Protein Stabilization
Chiasma Assembly
Protein Autoubiquitination
Canonical Wnt Signaling Pathway
Histone Lysine Demethylation
Synaptonemal Complex Organization
Protein K63-linked Ubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
22 interactors:
AMOTL2
ATM
CDC73
HIST1H2BB
HIST2H2AA3
HIST2H2AC
HIST2H2BE
HIST2H3C
HIST2H4A
HTT
ITSN2
MSL1
PA2G4
PAF1
SMURF2
UBC
UBE2A
UBE2B
UBE2E1
USHBP1
WAC
ZDHHC17
19 interactors:
BIRC2
CDKN1B
CNOT4
CRMP1
CTNNB1
HIST2H2AC
MED31
PCNA
RAD18
RNF20
RNF40
TRIM45
UBA1
UBC
UBR1
UBR2
UBR3
UBR5
UNC119
Entrez ID
56254
7320
HPRD ID
07410
01533
Ensembl ID
ENSG00000155827
ENSG00000119048
Uniprot IDs
Q5VTR2
P63146
PDB IDs
1JAS
1NXA
2Y4W
2YB6
2YBF
Enriched GO Terms of Interacting Partners
?
Histone Ubiquitination
Chromatin Organization
Histone Modification
Histone H2B Ubiquitination
Chromosome Organization
Protein Monoubiquitination
Chromatin Modification
Histone Monoubiquitination
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Negative Regulation Of Cellular Metabolic Process
Cell Cycle
Negative Regulation Of Transcription, DNA-templated
Organelle Organization
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Cellular Protein Modification Process
Chromatin Silencing
Protein K48-linked Ubiquitination
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Gene Expression
Regulation Of Cell Cycle
Negative Regulation Of Biosynthetic Process
Protein Catabolic Process
Protein Polyubiquitination
Cell Cycle Process
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteasomal Protein Catabolic Process
G1 DNA Damage Checkpoint
Negative Regulation Of Cell Cycle
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Gene Expression, Epigenetic
Negative Regulation Of Mitotic Cell Cycle
Negative Regulation Of Cellular Protein Catabolic Process
Cell Cycle Checkpoint
Regulation Of Cell Cycle Phase Transition
Regulation Of Cell Cycle Process
DNA Methylation On Cytosine
Negative Regulation Of Myeloid Cell Differentiation
Ubiquitin-dependent Protein Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Negative Regulation Of Chromosome Organization
Positive Regulation Of Signal Transduction
Cellular Macromolecule Catabolic Process
Proteasomal Protein Catabolic Process
Cellular Protein Metabolic Process
Histone H2A Ubiquitination
Positive Regulation Of MRNA 3'-end Processing
Chromatin Silencing At RDNA
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Macromolecule Catabolic Process
Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Catabolic Process
Cellular Response To Leucine
Proteolysis
Histone Ubiquitination
Cellular Protein Modification Process
Regulation Of Protein K63-linked Ubiquitination
Protein Polyubiquitination
Response To Cadmium Ion
Response To Leucine
Histone H2B Ubiquitination
Cellular Response To DNA Damage Stimulus
Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development
Response To Amino Acid
Cell Cycle Process
Positive Regulation Of Canonical Wnt Signaling Pathway
Cellular Protein Metabolic Process
Histone Monoubiquitination
Regulation Of Histone Modification
Response To Abiotic Stimulus
Positive Regulation Of Cellular Protein Metabolic Process
Protein Metabolic Process
Positive Regulation Of Wnt Signaling Pathway
G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of TOR Signaling
Negative Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Response To Organonitrogen Compound
Positive Regulation Of Histone Methylation
Regulation Of Nitrogen Compound Metabolic Process
Cell Cycle
Regulation Of Cellular Protein Metabolic Process
Intracellular Receptor Signaling Pathway
Regulation Of Chromosome Organization
Negative Regulation Of Protein Metabolic Process
Protein Monoubiquitination
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Modification Process
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Canonical Wnt Signaling Pathway
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Cellular Metabolic Process
Tagcloud
?
abundance
coincide
contributions
di
dot1l
drives
dynamic
e3
employ
evolutionarily
exhibit
garnered
h2b
h2bub1
h3k4me2
h3k79me2
implicate
lysines
mitosis
mitotic
normally
overlooked
patterning
ptm
reaches
requisite
rnai
stability
virtually
Tagcloud (Difference)
?
abundance
coincide
contributions
di
dot1l
drives
dynamic
e3
employ
evolutionarily
exhibit
garnered
h2b
h2bub1
h3k4me2
h3k79me2
implicate
lysines
mitosis
mitotic
normally
overlooked
patterning
ptm
reaches
requisite
rnai
stability
virtually
Tagcloud (Intersection)
?