NXF2 and NUP214

Number of citations of the paper that reports this interaction (PMID 11073998)
56

Data Source:
HPRD (in vitro)

		NXF2	NUP214
Gene Name		nuclear RNA export factor 2	nucleoporin 214kDa
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Nuclear RNA Export Factor Complex	Nucleus Nuclear Pore Nucleoplasm Cytosol Focal Adhesion Intracellular Membrane-bounded Organelle
	Molecular Function	Nucleotide Binding RNA Binding	Transporter Activity Nucleocytoplasmic Transporter Activity Protein Binding
	Biological Process	MRNA Export From Nucleus Multicellular Organismal Development RNA Transport	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Protein Import Into Nucleus Protein Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Regulation Of Cell Cycle Transmembrane Transport
Pathways			Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport HuR stabilizes mRNA M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Regulation of mRNA stability by proteins that bind AU-rich elements Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Regulation of Glucokinase by Glucokinase Regulatory Protein Nuclear Pore Complex (NPC) Disassembly Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: APEX1 APP HNRNPUL1 MAP1A MAP1B NUP153 NUP214 NUP62 NXF1 NXT1 NXT2	19 interactors: APC CLEC4G DDX19B IPO5 NFX1 NUP107 NUP88 NUPL2 NXF1 NXF2 NXF3 SMAD2 SMAD3 SMAD4 TNPO1 XPO1 XPO5 XPOT ZFP36
Entrez ID		56001	8021
HPRD ID		02260	00258
Ensembl ID		ENSG00000185554	ENSG00000126883
Uniprot IDs		Q9GZY0	P35658
PDB IDs			2OIT 3FHC 3FMO 3FMP
Enriched GO Terms of Interacting Partners?		RNA Transport RNA Localization MRNA Transport Nucleocytoplasmic Transport Nuclear Transport Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Intracellular Transport Nuclear Envelope Organization RNA Export From Nucleus Glucose Transport Hexose Transport Establishment Of Localization In Cell Cytoplasmic Transport Viral Transcription Regulation Of Glucose Transport Nuclear Export Nucleus Organization Carbohydrate Transport Cellular Localization Viral Process Viral Life Cycle Pathogenesis Protein Export From Nucleus Protein Transport Gene Expression Positive Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Positive Regulation Of Cell Cycle Phase Transition Establishment Of Protein Localization Transport MRNA Export From Nucleus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Developmental Cell Growth Endomembrane System Organization Cell Cycle Process Negative Regulation Of RNA Export From Nucleus Synaptic Growth At Neuromuscular Junction Viral Penetration Into Host Nucleus Cytokine-mediated Signaling Pathway Protein Localization Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Intracellular Transport Organelle Organization Collateral Sprouting In Absence Of Injury Nuclear Import RNA Metabolic Process Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport	Nucleocytoplasmic Transport Nuclear Transport Nuclear Export RNA Transport RNA Localization MRNA Transport Cytoplasmic Transport RNA Export From Nucleus Viral Process Gene Expression MRNA Export From Nucleus Establishment Of Localization In Cell Intracellular Transport Cellular Localization Protein Transport SMAD Protein Complex Assembly Establishment Of Protein Localization Gene Silencing By RNA Protein Localization Transport Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Gene Silencing Positive Regulation Of Epithelial To Mesenchymal Transition Protein Export From Nucleus Gene Silencing By MiRNA Mitotic Nuclear Envelope Disassembly Transforming Growth Factor Beta Receptor Signaling Pathway Posttranscriptional Gene Silencing Nuclear Envelope Disassembly Positive Regulation Of Stem Cell Differentiation SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Primary MiRNA Processing Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Regulation Of Cellular Response To Growth Factor Stimulus Viral Life Cycle Regulation Of Nucleocytoplasmic Transport Negative Regulation Of Transcription From RNA Polymerase II Promoter Nuclear Envelope Organization Somatic Stem Cell Maintenance Regulation Of Transforming Growth Factor Beta2 Production Paraxial Mesoderm Morphogenesis Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Glucose Transport Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Endoderm Development Hexose Transport Embryonic Pattern Specification
Tagcloud ?			acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Difference) ?			acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup153 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Intersection) ?