NXF2 and NXT1

Number of citations of the paper that reports this interaction (PMID 11073998)
56

Data Source:
HPRD (in vitro)

		NXF2	NXT1
Gene Name		nuclear RNA export factor 2	nuclear transport factor 2-like export factor 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Nuclear RNA Export Factor Complex	Nuclear Pore Cytoplasm Nuclear Speck
	Molecular Function	Nucleotide Binding RNA Binding	Protein Binding Ran GTPase Binding
	Biological Process	MRNA Export From Nucleus Multicellular Organismal Development RNA Transport	RNA Export From Nucleus Protein Export From Nucleus
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		11 interactors: APEX1 APP HNRNPUL1 MAP1A MAP1B NUP153 NUP214 NUP62 NXF1 NXT1 NXT2	8 interactors: DDOST NXF1 NXF2 NXF3 PAXIP1 RAN STAU1 XPO1
Entrez ID		56001	29107
HPRD ID		02260	16159
Ensembl ID		ENSG00000185554	ENSG00000132661
Uniprot IDs		Q9GZY0	Q9UKK6
PDB IDs			1JKG 1JN5
Enriched GO Terms of Interacting Partners?		RNA Transport RNA Localization MRNA Transport Nucleocytoplasmic Transport Nuclear Transport Mitotic Nuclear Envelope Disassembly Nuclear Envelope Disassembly Intracellular Transport Nuclear Envelope Organization RNA Export From Nucleus Glucose Transport Hexose Transport Establishment Of Localization In Cell Cytoplasmic Transport Viral Transcription Regulation Of Glucose Transport Nuclear Export Nucleus Organization Carbohydrate Transport Cellular Localization Viral Process Viral Life Cycle Pathogenesis Protein Export From Nucleus Protein Transport Gene Expression Positive Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Positive Regulation Of Cell Cycle Phase Transition Establishment Of Protein Localization Transport MRNA Export From Nucleus Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Developmental Cell Growth Endomembrane System Organization Cell Cycle Process Negative Regulation Of RNA Export From Nucleus Synaptic Growth At Neuromuscular Junction Viral Penetration Into Host Nucleus Cytokine-mediated Signaling Pathway Protein Localization Positive Regulation Of Mitotic Cell Cycle Negative Regulation Of Intracellular Transport Organelle Organization Collateral Sprouting In Absence Of Injury Nuclear Import RNA Metabolic Process Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport	Nuclear Export RNA Localization Nucleocytoplasmic Transport Nuclear Transport Cytoplasmic Transport MRNA Transport RNA Transport Ribosomal Small Subunit Export From Nucleus Cellular Localization MRNA Export From Nucleus RNA Export From Nucleus Intracellular Transport Ribosomal Large Subunit Export From Nucleus Ribosomal Subunit Export From Nucleus Poly(A)+ MRNA Export From Nucleus Establishment Of Localization In Cell Gene Expression Intracellular Transport Of Virus Protein Export From Nucleus Positive Regulation Of Histone H3-K36 Methylation Protein Localization To Organelle Viral Process Positive Regulation By Virus Of Viral Protein Levels In Host Cell Protein Localization To Nucleus Transport Ribosome Biogenesis Viral Life Cycle Intracellular Protein Transport Chorion Development Intracellular MRNA Localization Cellular Protein Complex Localization Ribonucleoprotein Complex Biogenesis Establishment Of Organelle Localization Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Histone H3-K4 Methylation Establishment Of Protein Localization To Organelle Positive Regulation Of DNA-templated Transcription, Initiation Protein Complex Localization Positive Regulation Of Histone Acetylation Positive Regulation Of Viral Genome Replication Regulation Of DNA-templated Transcription, Initiation Regulation Of Histone H3-K4 Methylation Cellular Protein Localization Organelle Localization Protein Targeting Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Isotype Switching Regulation Of Protein Export From Nucleus Positive Regulation Of Protein Acetylation Protein Transport
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