NSFL1C and PBK

Number of citations of the paper that reports this interaction (PubMedID 19900192)
29

Data Source:
BioGRID (pull down)

		NSFL1C	PBK
Description		NSFL1 cofactor	PDZ binding kinase
Image
GO Annotations	Cellular Component	Nucleus Chromosome Cytoplasm Golgi Apparatus Golgi Stack Centrosome Cytosol Cytoskeleton VCP-NSFL1C Complex	Nucleus
	Molecular Function	Protein Binding Lipid Binding Ubiquitin Binding	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity
	Biological Process	Autophagosome Assembly Establishment Of Mitotic Spindle Orientation Ubiquitin-dependent Protein Catabolic Process Golgi Organization Nuclear Membrane Reassembly Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Mitotic Centrosome Separation Membrane Fusion Negative Regulation Of Protein Localization To Centrosome	Mitotic Cell Cycle Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Stress-activated MAPK Cascade Cellular Response To UV Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Inflammatory Response Stress-activated MAPK Cascade
Pathways		RHOH GTPase cycle
Drugs
Diseases
GWAS
Interacting Genes		19 interacting genes: ANP32A CDK1 CEBPA DBI FAM32A GLMN GSK3B LIPE NEDD8 NGLY1 PBK PHAX PRKACA RPL22 SRP14 STX5 TARDBP UBC VCP	25 interacting genes: ARAF CCNB1 CDK1 CEP126 DLG1 GPRASP1 GPS2 H2AX LNX1 MCRS1 NSFL1C PPP1CA PRC1 PTEN PTOV1 RAF1 SMAD4 TERT TP53 TRIM37 UBC VCP ZBTB26 ZFP64 ZNF526
Entrez ID		55968	55872
HPRD ID		09425	17822
Ensembl ID		ENSG00000088833	ENSG00000168078
Uniprot IDs		Q53FE8 Q9UNZ2	Q96KB5 V9HWH0
PDB IDs		1SS6 8HRZ	5J0A
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Proteolysis Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Nucleocytoplasmic Transport Ubiquitin Protein Ligase Binding Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Intracellular Protein Transport Regulation Of Nucleocytoplasmic Transport Regulation Of Generation Of Precursor Metabolites And Energy Positive Regulation Of Intracellular Transport Golgi Disassembly Regulation Of Intracellular Protein Transport RNA Binding Modification-dependent Protein Catabolic Process Negative Regulation Of Catabolic Process Positive Regulation Of Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Organelle Disassembly Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Macromolecule Catabolic Process Protein Metabolic Process Protein Tag Activity Positive Regulation Of Protein Transport Regulation Of Intracellular Transport Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Export From Nucleus Regulation Of Circadian Rhythm Positive Regulation Of Proteasomal Protein Catabolic Process Intracellular Signaling Cassette Positive Regulation Of Catabolic Process Ubiquitin-dependent Protein Catabolic Process Glutamatergic Synapse Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Catabolic Process Protein Serine Kinase Activity Protein Phosphorylation Macromolecule Metabolic Process Nucleus Regulation Of Osteoblast Differentiation Regulation Of Primary Metabolic Process Regulation Of Protein Localization To Nucleus Negative Regulation Of Smoothened Signaling Pathway Regulation Of Protein Export From Nucleus Phosphorylation Catabolic Process Positive Regulation Of Protein Import Into Nucleus Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cell Cycle Microtubule Cytoskeleton Organization Cytoplasm Positive Regulation Of Macromolecule Metabolic Process Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin B1-CDK1 Complex VCP-NSFL1C Complex Intracellular Signaling Cassette Negative Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Organelle Organization Spindle Organization Centrosome Positive Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Nucleus Cytoskeleton Organization Regulation Of Mitotic Cell Cycle Phase Transition Protein Modification Process Negative Regulation Of Cell Cycle Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Microtubule-based Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Negative Regulation Of Cell Cycle Phase Transition MAPK Cascade Regulation Of RNA Metabolic Process Aggresome Assembly Positive Regulation Of Protein Localization To Nucleolus Positive Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Senescence Transcription Coactivator Binding Cellular Component Assembly Inclusion Body Assembly Cytosol Positive Regulation Of MiRNA Transcription DNA Metabolic Process Macromolecule Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle
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