PBK and ZFP64

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PBK	ZFP64
Description		PDZ binding kinase	ZFP64 zinc finger protein
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GO Annotations	Cellular Component	Nucleus	Nucleus Cytoplasm Megasporocyte Nucleus
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Mitotic Cell Cycle Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Stress-activated MAPK Cascade Cellular Response To UV Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Inflammatory Response Stress-activated MAPK Cascade	Positive Regulation Of Transcription By RNA Polymerase II Mesenchymal Cell Differentiation
Pathways
Drugs
Diseases
GWAS			Adult body size ( 32376654) Amyotrophic lateral sclerosis ( 17362836) Appendicular lean mass ( 33097823) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 25673413 28892062) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Hand grip strength ( 29691431) HDL cholesterol levels ( 32203549) Parkinson's disease ( 26227905) Reading disability or specific language impairment (pleiotropy) ( 25065397) Subcutaneous adipose tissue ( 22589738) Urinary metabolite levels in chronic kidney disease ( 29545352) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Waist circumference ( 25673412) Waist-hip ratio ( 25673412)
Interacting Genes		25 interacting genes: ARAF CCNB1 CDK1 CEP126 DLG1 GPRASP1 GPS2 H2AX LNX1 MCRS1 NSFL1C PPP1CA PRC1 PTEN PTOV1 RAF1 SMAD4 TERT TP53 TRIM37 UBC VCP ZBTB26 ZFP64 ZNF526	27 interacting genes: AEN BARD1 BEGAIN BYSL EMD ERG28 FAM124A FHL2 L3MBTL2 LMO2 LNX1 MAFB MFAP1 MTUS2 PBK PPARGC1B PRPF31 RBM10 RHOU SETDB1 TAB2 TLE1 TRIM41 UNC119 ZBTB9 ZNF513 ZNF70
Entrez ID		55872	55734
HPRD ID		17822	15728
Ensembl ID		ENSG00000168078	ENSG00000020256
Uniprot IDs		Q96KB5 V9HWH0	B3KQX0 Q9NTW7
PDB IDs		5J0A	1X5W 2DMD
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cell Cycle Microtubule Cytoskeleton Organization Cytoplasm Positive Regulation Of Macromolecule Metabolic Process Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin B1-CDK1 Complex VCP-NSFL1C Complex Intracellular Signaling Cassette Negative Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Organelle Organization Spindle Organization Centrosome Positive Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Nucleus Cytoskeleton Organization Regulation Of Mitotic Cell Cycle Phase Transition Protein Modification Process Negative Regulation Of Cell Cycle Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Microtubule-based Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Negative Regulation Of Cell Cycle Phase Transition MAPK Cascade Regulation Of RNA Metabolic Process Aggresome Assembly Positive Regulation Of Protein Localization To Nucleolus Positive Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Senescence Transcription Coactivator Binding Cellular Component Assembly Inclusion Body Assembly Cytosol Positive Regulation Of MiRNA Transcription DNA Metabolic Process Macromolecule Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle	Zinc Ion Binding Nucleus
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