PBK and CEP126

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PBK	CEP126
Description		PDZ binding kinase	centrosomal protein 126
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Centrosome Cytoskeleton Midbody Cell Projection Ciliary Base
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Protein Binding
	Biological Process	Mitotic Cell Cycle Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Stress-activated MAPK Cascade Cellular Response To UV Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Inflammatory Response Stress-activated MAPK Cascade	Mitotic Spindle Organization Cell Projection Organization Cytoplasmic Microtubule Organization Cilium Assembly Non-motile Cilium Assembly
Pathways
Drugs
Diseases
GWAS
Interacting Genes		25 interacting genes: ARAF CCNB1 CDK1 CEP126 DLG1 GPRASP1 GPS2 H2AX LNX1 MCRS1 NSFL1C PPP1CA PRC1 PTEN PTOV1 RAF1 SMAD4 TERT TP53 TRIM37 UBC VCP ZBTB26 ZFP64 ZNF526	87 interacting genes: AIMP2 AKTIP ARIH2 ATP6V1F ATRX BMI1 BRD1 C11orf58 CDKN2B CRCT1 CSTF2 DGCR6 DISC1 DLEU1 DNM1 DUSP12 DUSP23 EIF2S2 EIF6 EPN1 FAM118B FAM200C FEZ1 FGFR3 FXR1 GEMIN7 GET4 GIT1 GOLGB1 GPRASP2 GSTO1 HMOX2 HTT ING5 KAT5 KAT7 KIF15 KLHL20 LAMTOR5 LPL LRRC1 LUC7L2 MAD2L1BP MAPK9 MLH1 MRPS6 NAP1L5 NAT9 NPM3 NSF NUDT21 ODF2L OFD1 PBK PDCD5 PFDN1 PIK3R3 PMF1 POLD1 POLR2M PPP1CA PPP1CC PRKRA PTPRS RAB27A RAN RBM23 RETREG2 RGS2 RIF1 ROGDI RPA2 RUVBL1 SAT1 SNRPG SPDL1 STAU2 TFG TNFRSF14 TNFSF11 TOMM20 TTR TXNDC9 VIM YAE1 YWHAZ ZNF24
Entrez ID		55872	57562
HPRD ID		17822	17212
Ensembl ID		ENSG00000168078	ENSG00000110318
Uniprot IDs		Q96KB5 V9HWH0	Q9P2H0
PDB IDs		5J0A
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cell Cycle Microtubule Cytoskeleton Organization Cytoplasm Positive Regulation Of Macromolecule Metabolic Process Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin B1-CDK1 Complex VCP-NSFL1C Complex Intracellular Signaling Cassette Negative Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Organelle Organization Spindle Organization Centrosome Positive Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Nucleus Cytoskeleton Organization Regulation Of Mitotic Cell Cycle Phase Transition Protein Modification Process Negative Regulation Of Cell Cycle Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Microtubule-based Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Negative Regulation Of Cell Cycle Phase Transition MAPK Cascade Regulation Of RNA Metabolic Process Aggresome Assembly Positive Regulation Of Protein Localization To Nucleolus Positive Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Senescence Transcription Coactivator Binding Cellular Component Assembly Inclusion Body Assembly Cytosol Positive Regulation Of MiRNA Transcription DNA Metabolic Process Macromolecule Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle	Nucleus Organelle Organization Cytosol Histone H3-K14 Acetyltransferase Complex Protein Binding Establishment Of Organelle Localization Phosphoprotein Phosphatase Activity Microtubule Cytoskeleton Organization Involved In Mitosis Protein-RNA Complex Assembly DNA Replication-dependent Chromatin Disassembly Organelle Localization Cytoplasm Chromatin Binding Presynapse Axon Positive Regulation Of Aggrephagy Histone Acetyltransferase Complex DNA Repair Chromosome, Telomeric Region Regulation Of Circadian Rhythm Chromosome Organization
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