PBK and ZBTB26

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PBK	ZBTB26
Description		PDZ binding kinase	zinc finger and BTB domain containing 26
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Mitotic Cell Cycle Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Stress-activated MAPK Cascade Cellular Response To UV Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Inflammatory Response Stress-activated MAPK Cascade	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process
Pathways
Drugs
Diseases
GWAS			Appendicular lean mass ( 33097823) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		25 interacting genes: ARAF CCNB1 CDK1 CEP126 DLG1 GPRASP1 GPS2 H2AX LNX1 MCRS1 NSFL1C PPP1CA PRC1 PTEN PTOV1 RAF1 SMAD4 TERT TP53 TRIM37 UBC VCP ZBTB26 ZFP64 ZNF526	35 interacting genes: AXIN1 CARD10 CDC37 CDC7 CYP2W1 DAXX DRC4 DVL3 EHHADH EIF6 GIPC2 HMBOX1 L3MBTL2 LNX1 MORF4L1 MORF4L2 PBK PPL RAD23A RAD54L2 RNF4 SOX5 SUMO1 SUMO1P1 TRAF4 TRIM41 TSGA10 UBE2I ZBTB12 ZBTB34 ZBTB48 ZBTB6 ZBTB9 ZMYM5 ZNF408
Entrez ID		55872	57684
HPRD ID		17822	15692
Ensembl ID		ENSG00000168078	ENSG00000171448
Uniprot IDs		Q96KB5 V9HWH0	Q9HCK0
PDB IDs		5J0A
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cell Cycle Microtubule Cytoskeleton Organization Cytoplasm Positive Regulation Of Macromolecule Metabolic Process Microtubule Cytoskeleton Organization Involved In Mitosis Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Nucleobase-containing Compound Metabolic Process Cyclin B1-CDK1 Complex VCP-NSFL1C Complex Intracellular Signaling Cassette Negative Regulation Of Cell Cycle Process Regulation Of Cell Cycle Phase Transition Organelle Organization Spindle Organization Centrosome Positive Regulation Of RNA Metabolic Process Positive Regulation Of Metabolic Process Nucleus Cytoskeleton Organization Regulation Of Mitotic Cell Cycle Phase Transition Protein Modification Process Negative Regulation Of Cell Cycle Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Microtubule-based Process Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process Negative Regulation Of Cell Cycle Phase Transition MAPK Cascade Regulation Of RNA Metabolic Process Aggresome Assembly Positive Regulation Of Protein Localization To Nucleolus Positive Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Senescence Transcription Coactivator Binding Cellular Component Assembly Inclusion Body Assembly Cytosol Positive Regulation Of MiRNA Transcription DNA Metabolic Process Macromolecule Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of G1/S Transition Of Mitotic Cell Cycle	Regulation Of Primary Metabolic Process PML Body Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Transcription Factor Binding Nucleus Small Protein Activating Enzyme Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process PML Body Organization Nuclear Body Enzyme Binding Double-stranded Telomeric DNA Binding Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Sumoylation Zinc Ion Binding Negative Regulation Of RNA Metabolic Process Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Tag Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process Identical Protein Binding Positive Regulation Of Metabolic Process DNA Metabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nuclear Body Organization Positive Regulation Of Macromolecule Metabolic Process Ubiquitin-specific Protease Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Cadmium Ion Regulation Of Proteasomal Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Ubiquitin-like Protein Ligase Binding NuA4 Histone Acetyltransferase Complex Presynaptic Cytosol Response To Arsenic-containing Substance Postsynaptic Cytosol Positive Regulation Of Proteasomal Protein Catabolic Process
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